专利号:US-7968752-B2 优先权日:2003-06-16 标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use 发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A 权利人:ANACOR PHARMACEUTICALS INC 摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
专利号:US-8513465-B2 优先权日:2008-02-04 标题:Potassium organotrifluoroborate derivative and a production method therefor 发明人:KANG HEONJOONG; HAM JUNGYEOB; AHN HONG RYUL; PARK YOUNG HEE 权利人:KANG HEONJOONG; HAM JUNGYEOB; AHN HONG RYUL; PARK YOUNG HEE; SNU R&DB FOUNDATION 摘要:Provided are a production method for a potassium organotrifluoroborate compound having a hydroxyl group, and a novel potassium organotrifluoroborate compound having a hydroxyl group. The production method is advantageous in that a potassium organotrifluoroborate compound can be produced in a single reaction without recourse to a process of isolating and purifying an intermediate. The novel potassium organotrifluoroborate compound having a hydroxyl group is useful as a reactant which is widely used in the total synthesis of physiologically active natural products and diverse organic synthesis reactions including halogen substitution reactions, 1,2- and 1,4-addition reactions using a rhodium (Rh) catalyst, and Suzuki coupling reactions using a palladium (Pd) catalyst.
专利号:US-6416861-B1 优先权日:1999-02-16 标题 :Organosilicon compounds and uses thereof 发明人:LEE YOUNGHEE; SILVERMAN RICHARD B 权利人:UNIV NORTHWESTERN 摘要:A compound of the formula: n and a resin-bound compound of the formula: n and their use in combinatorial chemistry and in the synthesis of compounds comprising at least one aromatic moiety is described, where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , P, Ar 1 , and X are as herein defined.
专利号:EP-1090008-A4 优先权日:1998-06-25 标 题:SYNTHESIS OF A VARIETY OF LAMELLARINE COMPOUNDS AND ANALOG
专利号:WO-2013102935-A2 优先权日:2012-01-03 标 题:Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES
专利号:JP-2002518503-A 优先权日:1998-06-25 标 题 :Synthesis of various lamellar compounds and analogs
[参考文献]: Polina V Oliferenko, Et Al. Promising Aedes Aegypti Repellent Chemotypes Identified Through Integrated Qsar, Virtual Screening, Synthesis, And Bioassay. Plos One. 2013 Sep 6;8(9):E64547.
合成参考文献
摘要:Eichman, C. C.; Stambuli, J. P., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 370. 摘要:Eichman, C. C.; Stambuli, J. P., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 374.