专利号:EP-0180398-A1 优先权日:1984-10-26 标 题:Synthesis of beta-lactam 发明人:OVERMAN LARRY E; OSAWA TATSUSHI 权利人:UNIV CALIFORNIA 摘要:A method of synthesizing monomeric formadelhyde imines in situ by reacting (cyanomethyl)- or (aminomethyl)-amines with organometal or Grignard reagents, and their use to synthesize 2-azetidinones (β-lactams) via reaction with enolates.
专利号:EP-0528629-A2 优先权日:1991-08-12 标题:Enzymatic synthesis of renin inhibitors
专利号:CA-2075771-A1 优先权日:1991-08-12 标题:Enzymatic synthesis of renin inhibitors
专利号:CN-115417803-B 优先权日:2022-08-30 标题 :Synthesis method of upadatinib intermediate (3R,4S)-1-benzyloxycarbonyl-4-ethylpyrrolidine-3-carboxylic acid
参考标题:Amino Acids And Peptides. Xii. Phosphorus In Organic Synthesis. Viii. Reaction Of Malonic Acid Half Esters With Diphenyl Phosphorazidate 作者:Kunihiro Ninomiya,Takayuki Shioiri,Shunichi Yamada 摘要:Application Of The Modified Curtius Reaction By Dppa To Some Malonic Acid Half Esters Revealed That Esterification Occurred In A One-Step Process But The Rearrangement Reaction Took Place In A Two-In-One-Reaction Procedure, The Results Of Which Are Summarized In Tables I And Ii. The Latter Procedure May Provide A New Simple Method For The Synthesis Of α-Amino Acids.