专利号:US-2017275287-A1 优先权日:2014-08-22 标 题 :Novel n2, n4, n7, 6-tetrasubstituted pteridine-2,4,7-triamine and 2, 4, 6, 7-tetrasubstituted pteridine compounds and methods of synthesis and use thereof 发明人:LIPFORD GRAYSON B; ZEPP CHARLES M 权利人:JANUS BIOTHERAPEUTICS INC 摘要:Compounds as immune system modulators bearing a pteridine core are described. A pharmaceutical composition comprising the same, methods of making the same, and a method for treating or preventing autoimmunity disease using the same are described.
专利号:EP-3183251-A1 优先权日:2014-08-22 标题 :Novel n2, n4, n7, 6-tetrasubstituted pteridine-2,4,7-triamine and 2, 4, 6, 7-tetrasubstituted pteridine compounds and methods of synthesis and use thereof
专利号:EP-3398948-A2 优先权日:2014-08-22 标题 :2,4,6,7-tetrasubstituted pteridine compounds and methods of synthesis and use thereof
专利号:WO-2016029077-A1 优先权日:2014-08-22 标题:Novel n2, n4, n7, 6-tetrasubstituted pteridine-2,4,7-triamine and 2, 4, 6, 7-tetrasubstituted pteridine compounds and methods of synthesis and use thereof
参考文献:10.1177/1087057116635503 摘要:Voter AF, Manthei KA, Keck JL. A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. J Biomol Screen. 2016 Jul;21(6):626–33.