CAS: 23719-80-4; Magnesium,Cyclopropane,Bromide

上下游产品

diethyl ether cyclopropyl bromide 4-(trifluoromethoxy)benzonitrile(2E,4E)-hepta-2,4-dienal 2-Cyclopropyl-3-phenyl-2-butanol 1,1-Dicyclopropyl-2,2-diphenyl-ethanol 2,2-diphenyl-1-cyclopropylethan-1-one

溴代环丙烷置于magnesium体系中,用 四氢呋喃 用作溶剂,化学反应 5.5H,以98%的收率获得环丙基溴化镁
参考文献:铁催化的格氏试剂与甲基和环丙基格氏试剂的δ选择性共轭加成反应,生成不饱和的α,β,γ,δ酯和酰胺
标题:铁催化的格氏试剂与甲基和环丙基格氏试剂的δ选择性共轭加成反应,生成不饱和的α,β,γ,δ酯和酰胺
摘要:铁催化的格氏试剂甲基和环丙基格氏试剂的δ选择性共轭加成反应,收率很高,仅得到具有顺式-β,γ-烯烃键的产物.
Doi:10.1016/j.Tetlet.2018.12.043

专利信息

专利号:US-2024174698-A1
优先权日:2022-09-23
标题 :Modular synthesis of 1,2-azaborines via ring-opening bn-isostere benzannulation
发明人：DONG GUANGBIN; LYU HAIRONG; CHEN ZHIJIE; WU YIFEI; CHOI SHINYOUNG
权利人:UNIV CHICAGO
摘要:The present disclosure relates generally to 1,2-azaborines and methods of making the same.

专利号:US-3825607-A
优先权日:1972-01-17
标题 :Synthesis of 1-bromo-trans-3,trans-5-heptadiene
发明人：DESCOINS C; HENRICK C
权利人:ZOECON CORP
摘要:1-HALO-3,5-HEPTADIENE, PREPARED BY THE ACTION OF AQUEOUS HYDROPHALIC ACID ON 1-CYCLOPRROPYL-2-BUTEN-1-OL WHICH MAY BE PREPARED BY A GRIGNARD REACTION BETWEEN CROTONALDEHYDE AND CYCLOPROPYL MAGNESIUM HALLIDE OR BETWEEN CYCLOPROPYL CYANIDE AND 1-PROPYNYL MAGNESIUM HALIDE. IT IS USEFUL IN PREPARING 8.10-DODECADIENOL, A KNOWN CODLING MOTH SEX ATTRACTANT.

专利号:US-9296709-B2
优先权日:2012-07-03
标 题 :Manufacture of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid
发明人：GUNIC ESMIR; GALVIN GABRIEL
权利人:ARDEA BIOSCIENCES INC
摘要:Described herein are certain processes for the synthesis of compounds of Formula (I):

专利号:US-8207337-B2
优先权日:2007-01-29
标 题:Reagent for organic synthesis reaction containing organic triol borate salt
发明人：MIYAURA NORIO; YAMAMOTO YASUNORI
权利人:MIYAURA NORIO; YAMAMOTO YASUNORI; WAKO PURE CHEM IND LTD
摘要:[Problem] n To provide an organoboron compound-containing reagent for organic synthesis reactions which undergoes no trimerization with dehydration, does not necessitate activation with a base, and is stable and highly active. n [Means for Solving Problems] n The reagent for organic synthesis reactions contains an organic triol borate salt represented by any of the general formulae (I) to (III) and general formula (XVI): (wherein R 1 represents alkyl, alkenyl, etc.; R 2 represents optionally substituted alkyl, alkenyl, alkynyl, etc. or represents hydrogen; m + represents an alkaline metal ion, phosphonium ion, or given ammonium ion; M 2+ represents an alkaline earth metal; X represents halogen or alkoxide; Y represents an alkali metal ion, etc.; A represents optionally substituted methylene; and n represents an integer).

专利号:US-2024400552-A1
优先权日:2016-11-11
标题 :Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by dysregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).

专利号:US-11622968-B2
优先权日:2011-03-08
标 题:Heterocyclic modulators of lipid synthesis
发明人：BUCKLEY DOUGLAS; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
权利人:SAGIMET BIOSCIENCES INC
摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).