CAS: 540-88-5; Tert-Butyl Acetate

上下游产品

CAS号75-36-5 乙酰氯 | CAS号75-65-0 叔丁醇 | CAS号75-97-8 频那酮 | CAS号108-24-7 乙酸酐 | CAS号372-19-0 3-氟苯胺 | CAS号5292-43-3 溴乙酸叔丁酯 | CAS号64-19-7 冰醋酸 | CAS号115-11-7 2-甲基丙烯 | CAS号1118-32-7 Propanamide,N-(... | CAS号104847-07-6 N-叔丁基-2-甲基苯甲酰胺 | CAS号32677-01-3 L-谷氨酸二叔丁酯盐酸盐 | CAS号562-90-3 正硅酸四乙酯 | CAS号32864-38-3 丙二酸叔丁基乙酯 | CAS号344-62-7 2'-(三氟甲基)乙酰苯胺 | CAS号5545-52-8 N-苄氧羰基-L-天门冬氨酸 4-叔丁酯 | CAS号42417-76-5 Z-L-天冬氨酸叔丁酯叔丁酯 | CAS号375846-25-6 氟伐醇酮

频哪酮置于recl3{hc(Pyrazolyl)3},双氧水体系中,用 水,1,2-二氯乙烷 作为反应溶剂,化学反应 6.0H,以12%的收率获得产物醋酸叔丁酯
参考文献:轴承由铼络合物催化的酮的拜尔-维利格氧化ñ或氧代配位体-
标题:轴承由铼络合物催化的酮的拜尔-维利格氧化ñ或氧代配位体-
摘要:带有n-给体或含氧配体的hen (i,Iii-V或vii)络合物催化环状和线性酮(例如2-甲基环己酮,2-甲基环戊酮,环己酮,环戊酮,环丁酮和3,3-酮)的baeyer-Villiger氧化.在含水H2O 2(30%)存在下,将其转化为相应的内酯或酯.研究了各种反应参数的影响,可实现高达54%的收率.
DOI:10.1016/j.Apcata.2012.07.007

专利信息

专利号:US-10189803-B2
优先权日:2008-02-22
标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-8822702-B2
优先权日:2002-12-20
标 题 :Synthesis of amines and intermediates for the synthesis thereof
发明人：BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL
权利人:BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL; BASF SE
摘要:The invention relates in a first embodiment to a method for the manufacture of esters of the formula I, n nor especially of amides of the formula II,n n nwherein the symbols have the meanings given in the specification, as well as other intermediates and compounds useful in the synthesis of tryptamines and other substances mentioned in the title. The synthesis methods and intermediates are useful in the synthesis of pharmaceuticals.

专利号:WO-2019170521-A1
优先权日:2018-03-07
标题 :Synthesis of obeticholic acid and synthesis intermediate
发明人：BERNABEU MARTÃ?NEZ MARÃ?A DEL CARMEN; JIMÉNEZ ALONSO OSCAR; DOBARRO RODRÃ?GUEZ ALICIA; GABOARDI MAURO; CASTALDI GRAZIANO
权利人:MOEHS IBERICA SL
摘要:The present invention relates to a new intermediate for the synthesis of obeticholic acid, the compound of formula (I) or a geometric isomer thereof, a process for obtaining the same, as well as the use of said intermediate in the synthesis of obeticholic acid.

专利号:US-2004018598-A1
优先权日:2000-05-30
标题 :Bio-intermediates for use in the chemical synthesis of polyketides
发明人：SANTI DANIEL; ASHLEY GARY; MYLES DAVID C
摘要:The present invention relates to compounds made by a subset of modules from one or more polyketide synthase (“PKSâ€?) genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring polyketides or derivatives thereof. The biologically derived intermediates (“bio-intermediatesâ€?) generally represent particularly difficult compounds to synthesize using traditional chemical approaches due to one or more stereocenters. In one aspect of the invention, an intermediate in the synthesis of epothilone is provided that feeds into the synthetic protocol of Danishefsky and co-workers. In another aspect of the invention, intermediates in the synthesis of discodermolide are provided that feed into the synthetic protocol of Smith and co-workers. By taking advantage of the inherent stereochemical specificity of biological processes, the syntheses of key intermediates and thus the overall syntheses of compounds like epothilone and discodermolide are greaty simplified.

专利号:US-2022298204-A1
优先权日:2019-07-05
标题 :Synthesis of a-amanitin and its derivatives
发明人：SIEGERT MARY-ANN; KNITTEL CAROLINE HERTA; SÃœSSMUTH RODERICH
权利人:PURE BIOORGANICS SIA
摘要:The present invention relates to the chemical synthesis of α-amanitin and its derivatives. The present invention also relates to intermediate products of the α-amanitin synthesis.

专利号:US-8293930-B1
优先权日:2004-06-25
标题 :One pot synthesis of taxane derivatives and their conversion to paclitaxel and docetaxel
发明人：NAIDU RAGINA
权利人:NAIDU RAGINA; CHATHAM BIOTEC LTD
摘要:A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediate in a one pot reaction of protecting the C-7 and C-10 positions and attaching a side chain at the C-13 position and subsequently deprotecting the group to form paclitaxel or docetaxel, and taxane intermediates.