CAS: 610-22-0; Dimethyl 4-Nitrophthalate

上下游产品

methanol 4-nitrophthalic acid 4-nitrophthalic acid chloride phthalic acid dimethyl ester4-aminophthalic acid 4-amino-phthalic acid dimethyl ester dimethyl 4-(2,2,2-trifluoroethoxy)phthalate dimethyl 4-(2,2,3,3,4,4,4-heptafluorobutoxy)phthalate

邻苯二甲酸二甲酯置于三氯化铁,二氧化氮,臭氧体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 1.5H,以52%的收率获得产物3-硝基-邻苯二甲酯
参考文献:苯二羧酸和萘羧酸酯的非酸硝化.
标题:苯二羧酸和萘羧酸酯的非酸硝化.
摘要:当在惰性有机溶剂中于-10至+5摄氏度,在臭氧和催化量的氯化铁(iii)的存在下用二氧化氮处理时,苯二甲酸二酯1,4和6进行平稳硝化,得到相应的单硝基衍生物2 / 3,5和7的收率很高(共硝化).在不存在催化剂的情况下,类似地硝化萘甲酸酯酯8和11以及萘-1,8-二羧酸二酯16,分别得到预期的硝基化合物9 / 10,12-15和17-22.与基于浓硝酸和硫酸的组合使用的常规硝化不同,在这些条件下未观测到酯官能团的水解裂解.已经确定了萘羧酸8,11和16硝化的异构体分布 并收集了不太常见的硝基衍生物的光谱数据.根据涉及硝基氮离子(no2 +)的亲电子取代过程与氢键之间的竞争,讨论了在二酯16的kyodai硝化反应中观测到的取向模式从最初的唯一间位到最终的间位/对位的独特转变.涉及三氧化氮自由基(* No3)的加成-消除序列.
DOI:10.1021/jo015619D

专利信息

专利号:WO-9509170-A1
优先权日:1993-09-28
标 题:Chemical synthesis of rhodamine derivatives
发明人：CORRIE JOHN EDGAR THOMAS; CRAIK JAMES STANLEY
权利人:MEDICAL RES COUNCIL; CORRIE JOHN EDGAR THOMAS; CRAIK JAMES STANLEY
摘要:A method for preparing rhodamine derivatives of formulae (a) or (b) or a mixture of such compounds, where X is bromo, chloro- or iodoacetamido, maleimido, or amino. These compounds are the 5 and 6 (or 5' and 6') isomers of the amine, haloacetamide and maleimide derivatives of tetramethylrhodamine. The method enables for the first time the production of isomerically pure compounds on a relatively large scale. The products are fluorescent and are useful for the labelling of proteins.

专利号:US-4002664-A
优先权日:1973-06-09
标题 :Manufacture of dimethylaminobenzenecarboxylic acid esters
发明人：QUADBECK-SEEGER HANS-JUERGEN; HOCH HELMUT
权利人:BASF AG
摘要:Dimethylaminobenzenecarboxylic acid esters are produced by reaction of nitrobenzenecarboxylic acid esters with formaldehyde and hydrogen under pressure in the presence of a hydrogenation catalyst containing metals of atomic numbers 24 to 29 and of a weak acid, at temperatures from 35° to 150° C. The products are starting materials for the synthesis of dyes, especially of crystal violets, and of reactive dyes and pesticides.

专利号:EP-0063945-A1
优先权日:1981-04-27
标 题 :Process for the regiospecific synthesis of anthracyclinone compounds such as daunomycinone

专利号:CN-104530221-A
优先权日:2014-12-17
标题 :A kind of synthesis method of phthalate compound general artificial antigen