CAS: 613-87-6; (S)-1-Phenyl-1-Propanol

上下游产品

CAS号97-93-8 三乙基铝 | CAS号100-52-7 苯甲醛 | CAS号93-55-0 苯丙酮 | CAS号93-54-9 1-苯基-1-丙醇 | CAS号557-20-0 二乙基锌 | CAS号108-22-5 醋酸异丙烯酯 | CAS号873-66-5 反-β-甲基苯乙烯 | CAS号766-90-5 顺-β-甲基苯乙烯 | CAS号172842-11-4 (R,R)-bis[2-[1-... | CAS号815610-79-8 (E)-O-((S)-1-ph... | CAS号118-12-7 1,3,3-三甲基-2-亚甲基吲哚啉 | CAS号1678-92-8 正丙基环己烷 | CAS号110529-28-7 (S)-(-)-1-cyclo...

正丙基苯置于盐酸,Ferrocenium(Iii) Tetrafluoroborate,Ethylbenzene Dehydrogenase体系中,用 水,叔丁醇 作为反应溶剂,以100%的收率获得产物
参考文献:乙苯脱氢酶对烷基芳族化合物厌氧羟基化对映选择性的机理基础
标题:乙苯脱氢酶对烷基芳族化合物厌氧羟基化对映选择性的机理基础
摘要:通过手性色谱和理论模型研究了乙苯脱氢酶(一种钼酶,催化许多烷基芳族和烷基杂环化合物向仲醇的不依赖氧的羟基化反应)催化的对映选择性.对22种底物的色谱分析表明,该酶对(S)-仲醇具有极高的反应对映选择性(18种底物的ee转化率> 99%).使用理论qm:Mm建模来阐明酶催化活性形式的结构,并研究决定其高对映选择性的反应机理和因素.该分析表明,该酶通过区分从底物提取的氢原子,对该反应强加了立体选择性.计算出pro(S)氢原子的活化比pro(R)氢原子的活化快500倍.实际的羟基化步骤(即羟基与碳正离子中间体的反弹反应)似乎没有足够的对映体选择性来解释实验数据(pro(S):Pro([r)导向的oh反弹).
DOI:10.1016/j.Jinorgbio.2014.05.006

专利信息

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-2013316397-A1
优先权日:2012-04-30
标 题:Cell-Free Polypeptide Synthesis
发明人：AIREN ISOKEN; SWARTZ JAMES ROBERT
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Methods, microbial strains and reaction mixtures for cell-free synthesis of polypeptides are provided. The methods of the invention utilize a reaction mixture comprising microbial cell extracts that are modified in the protein component relative to an extract from a native cell. The modification may be one or both of (i) increased levels of proteins that increase synthetic yield; and (ii) decreased levels of proteins that decrease synthetic yield. The modification may result from a genetic modification of the microbial cell, or from ex vivo supplementation or depletion of an extract.

专利号:WO-9318787-A1
优先权日:1992-03-25
标 题 :Trans-sialidase and methods of use and making thereof
发明人：NUSSENZWEIG VICTOR; SCHENKMAN SERGIO; EICHINGER DAN; VANDEKERCKHOVE FLIP
权利人:UNIV NEW YORK
摘要:Polypeptides are provided having trans-sialidase enzymatic activity in substantially pure form, nucleic acids coding therefor, antibodies specific for such polypeptides, processes for producing the enzyme and methods of use of the enzyme, in particular for the synthesis of sialyl α(2â†?3)-linked saccharides, glycoproteins and glycolipids. Such enzymes are isolatable as nucleic acid or amino acid sequences from parasites of the genus Trypanosoma.

专利号:US-2021284668-A1
优先权日:2018-06-19
标题:Gold (i)-phosphine 1,2,3-triazole derivatives with antibiotic properties
发明人：MISLIN GAËTAN; SCHALK ISABELLE; PLÉSIAT PATRICK; PAULEN AURÉLIE
权利人:CENTRE NAT RECH SCIENT; UNIV FRANCHE COMTE; CENTRE HOSPITALIER REGIONAL UNIV DE BESANCON; UNIV STRASBOURG
摘要:The present invention relates to gold (I)-phosphine 1,2,3-triazole compounds, and their use in a human or animal medicine. The present invention also relates to using such compounds for the prevention and/or treatment of an infection, i.e. inhibitors of growth of Gram-positive and/or Gram-negative bacteria. On another aspect the invention relates to the synthesis of the gold (I)-phosphine compounds of the invention and to their synthesis intermediates. The present invention finds applications in the medical, veterinary and/or chemical fields.

专利号:CN-1226099-C
优先权日:2002-09-17
标 题 :Chiral iridium catalyst, preparation method thereof and application in industrial synthesis of chiral alcohols

专利号:CN-1513598-A
优先权日:2002-09-17
标题 :Chiral iridium catalyst and its preparation method and its application in industrial synthesis of chiral alcohol