3-Silanylpropanenitrile置于氢氧化钾体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成3-(三甲氧基甲硅烷基)丙酰腈 参考文献:Mileshkevich,V.P.; Novikova,N.F.,Journal Of General Chemistry Of The Ussr,1978,Vol. 48,P. 1022-1025 标题:Mileshkevich,V.P.; Novikova,N.F.,Journal Of General Chemistry Of The Ussr,1978,Vol. 48,P. 1022-1025
专利号:US-9981239-B2 优先权日:2015-04-21 标题:Devices and methods for oligonucleic acid library synthesis 发明人:BANYAI WILLIAM; PECK BILL JAMES; FERNANDEZ ANDRES; CHEN SIYUAN; INDERMUHLE PIERRE; MARSH EUGENE P 权利人:TWIST BIOSCIENCE CORP 摘要:Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
专利号:WO-2023237381-A1 优先权日:2022-06-09 标题:Process for the synthesis of polyethylenes or copolymers of ethylene and 1,3-diene having a terminal ketone function 发明人:BOISSON CHRISTOPHE; D'AGOSTO FRANCK; DESGRANGES ARIANE; NGO ROBERT; JEAN-BAPTISTE-DIT-DOMINIQUE FRANÇOIS 权利人:MICHELIN & CIE; CENTRE NAT RECH SCIENT; ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE LYON; UNIV CLAUDE BERNARD LYON 摘要:The invention relates to a method for preparing a polyethylene having a terminal ketone function or a copolymer of ethylene and a 1,3-diene and optionally a vinyl aromatic compound which contains more than 50 mol% of ethylene and has a terminal ketone function; said method comprises a polymerization reaction of the monomers in the presence of a borohydrido-neodymocene complex and an organo-magnesium compound, followed by a coupling reaction with a compound having a nitrile function, and then a hydrolysis reaction.
专利号:US-6680013-B1 优先权日:1999-04-15 标题 :Synthesis of macroporous structures 发明人:STEIN ANDREAS; HOLLAND BRIAN T; BLANFORD CHRISTOPHER F; YAN HONGWEI 权利人:UNIV MINNESOTA 摘要:The present application discloses a method of forming an inorganic macroporous material. In some embodiments, the method includes: providing a sample of organic polymer particles having a particle size distribution of no greater than about 10%; forming a colloidal crystal template of the sample of organic polymer particles, the colloidal crystal template including a plurality of organic polymer particles and interstitial spaces therebetween; adding an inorganic precursor composition including a noncolloidal inorganic precursor to the colloidal crystal template such that the precursor composition permeates the interstitial spaces between the organic polymer particles; converting the noncolloidal inorganic precursor to a hardened inorganic framework; and removing the colloidal crystal template from the hardened inorganic framework to form a macroporous material. Inorganic macroporous materials are also disclosed.
专利号:WO-2023196499-A1 优先权日:2022-04-07 标 题:Substrate cleavage for nucleic acid synthesis 发明人:LACKEY JEREMY; DODD DAVID; LANGNER HEERA 权利人:TWIST BIOSCIENCE CORP 摘要:Disclosed herein are methods and compositions for cleavage of nucleic acids from a surface of a solid support. Further described herein are cleavage methods compatible with enzymatic and chemical nucleic acid synthesis methods.
专利号:US-2018104664-A1 优先权日:2016-08-03 标 题 :Textured surfaces for polynucleotide synthesis 发明人:FERNANDEZ ANDRES; INDERMUHLE PIERRE; MARSH EUGENE P; BANYAI WILLIAM; PECK BILL JAMES 权利人:TWIST BIOSCIENCE CORP 摘要:Methods, devices and systems are provided herein for surfaces for de novo polynucleotide synthesis that provide for increased polynucleotide yield. Surfaces described herein comprise a texture that increases surface area provide for increased polynucleotide yield compared to non-textured surfaces. In addition, the patterned placement of nucleoside coupling reagent spanning such surfaces provides for improved synthesis yield, representation, and a reduction in contamination on the surface between different polynucleotide species.
专利号:CN-119343386-A 优先权日:2022-06-09 标 题:Synthesis of polyethylene or copolymer of ethylene and 1, 3-diene having terminal ketone function