CAS: 2629-55-2; 2-Amino-3-(2-Fluorophenyl)Propanoic Acid

相似化合物

97731-02-7 114873-00-6 114873-10-8

上下游产品

CAS号345-35-7 邻氟氯苄 | CAS号446-52-6 邻氟苯甲醛 | CAS号66574-84-3 N-乙酰基-2-氟-DL-苯丙氨酸 | CAS号446-24-2 2-氟亚苯基肼 | CAS号443-26-5 邻氟苯甲酸乙酯 | CAS号380-69-8 acetylamino-(2-... | CAS号363-35-9 N-benzenesulfon... | CAS号97731-02-7 D-2-氟苯丙氨酸 | CAS号19883-78-4 2-氟-L-苯丙氨酸 | CAS号39801-61-1 Phenylalanine,2...

2-氟亚苯基肼置于磷化氢,氢碘酸,Sodium Acetate,乙酸酐体系中,化学反应生成2-氟-Dl-苯丙氨酸
参考文献:The Synthesis Of 2-Fluoro-Dl-Tyrosine And 2-Fluoro-4-Methoxy-Dl-Phenylalanine
标题:The Synthesis Of 2-Fluoro-Dl-Tyrosine And 2-Fluoro-4-Methoxy-Dl-Phenylalanine
摘要:
Doi:10.1021/ja01160A113

专利信息

专利号:US-9938509-B2
优先权日:2010-12-08
标 题 :Biocatalysts and methods for the synthesis of armodafinil
发明人：ANG EE LUI; ALVIZO OSCAR; BEHROUZIAN BEHNAZ; CLAY MICHAEL D; COLLIER STEVEN J; EBERHARD ELLEN D; FAN FU; SONG SHIWEI; SMITH DEREK J; WIDEGREN MAGNUS; WILSON ROBERT; XU JUNYE; ZHU JUN
权利人:CODEXIS INC
摘要:The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (−)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.

专利号:US-12378290-B2
优先权日:2019-09-05
标题:Method for protein nanowire synthesis and tunable control of nanowire length
发明人：REGUERA GEMMA; COSERT KRISTA MARIE
权利人:UNIV MICHIGAN STATE
摘要:Methods for synthesizing nanowires are provided. Modified PilA peptides are used as peptide building blocks for synthesizing the nanowires. The method places the peptide building blocks in an assembly buffer with a hydrophobe. Addition of a hydrophobe and molecular crowding by evaporation of the assembly buffer triggers the self-assembly of the peptide building blocks into fibers. Multiple elongation cycles of addition of peptide building blocks, mixing and evaporation are conducted to promote elongation of the fibers and synthesis of nanowires. Electronic characterization of the synthesized nanowires is provided.

专利号:US-9663771-B2
优先权日:2013-01-18
标题 :Engineered biocatalysts useful for carbapenem synthesis
发明人：SUKUMARAN JOLY; SMITH DEREK; YANG HONG; YEO WAN LIN; MOORE JEFFREY C
权利人:CODEXIS INC
摘要:The present disclosure provides engineered pNB esterase polypeptides useful for the synthesis of the carbapenem antibiotic, imipenem. The disclosure also provides polynucleotides encoding the engineered pNB esterases, host cells capable of expressing the engineered pNB esterases, and methods of using the engineered pNB esterases in the production of imipenem.

专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:US-12410410-B2
优先权日:2015-02-10
标题 :Ketoreductase polypeptides for the synthesis of chiral compounds
发明人：ALVIZO OSCAR; AGARD NICHOLAS J; XIE XINKAI; ENTWISTLE DAVID; KOSJEK BIRGIT
权利人:CODEXIS INC
摘要:The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.

专利号:EP-4424821-A1
优先权日:2023-03-01
标题:Enzymatic synthesis of odilorhabdin and related peptides/proteins comprising non-standard amino acid residues
权利人:MAX PLANCK GESELLSCHAFT
摘要:The present invention relates to a novel method of preparing a non-standard amino acid or a peptide/protein comprising a non-standard amino acid residue, as appropriate, wherein said amino acid residue is selected from 2,4-diamino-3-hydroxybutyrate, L-5-hydroxylysine, L-3-hydroxyarginine, 2,3-didehydroarginine by using enzymatic transformations. Accordingly, the present invention further relates to a method of preparing a peptide/protein comprising one or more non-standard amino acids selected from 2,4-diamino-3-hydroxybutyrate, L-5-hydroxylysine, L-3-hydroxyarginine and 2,3-didehydroarginine. The methods of the present invention are particularly useful in enzyme-assisted preparation of odilorhabdins and their derivatives. The present invention further relates to a polypeptide having 2,4-diaminobutyrate-3-hydroxylase activity and its use for catalyzing a hydroxylation at position 3 of 2,4-diaminobutyrate, to a polypeptide having having L-arginine 3-hydroxylase activity and its use for catalyzing a hydroxylation at position 5 of L-lysine, to a polypeptide having L-arginine 3-hydroxylase activity and its use for for catalyzing a hydroxylation at position 3 of L-arginine, and to a polypeptide having a deacylase activity, which is preferably capable of removing fatty acyl from the N-terminus of an odilorhabdin, and its use for catalyzing a deacylation, preferably for removing a fatty acyl from the N-terminus of an odilorhabdin.