CAS: 2521-24-6; 4-Chlorothiobenzamide

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CAS号104-88-1 对氯苯甲醛 | CAS号619-56-7 4-氯苯甲酰胺 | CAS号623-03-0 对氯苯腈 | CAS号3848-36-0 4-氯苯甲醛肟 | CAS号144-55-8 碳酸氢钠 | CAS号62-55-5 硫代乙酰胺 | CAS号74-11-3 对氯苯甲酸 | CAS号122-01-0 4-氯苯甲酰氯 | CAS号45709-05-5 (4-chlorophenyl... | CAS号337924-65-9 2-(4-氯苯基)-4-甲基-... | CAS号1433-65-4 2-(4-chlorophen... | CAS号2227-72-7 2-(4-chlorophen... | CAS号623-03-0 对氯苯腈 | CAS号4115-17-7 3,5-bis(4-chlor... | CAS号17797-11-4 2-(4-氯苯基)丙-2-胺 | CAS号538-74-9 二苄基硫醚 | CAS号23821-72-9 2-[2-(4-氯苯基)-4-... | CAS号27149-26-4 2-(4-氯苯基)噻唑 | CAS号74466-94-7 5-(4-氯苯基)-3-噻二唑...

5-(4-Chlorphenyl)-1,2,4-Dithiazol-3-On置于l-半胱氨酸体系中,用 Aq. Phosphate Buffer,二甲基亚砜 用作溶剂,化学反应生成4-氯硫代苯甲酰胺
参考文献: Compounds For Thiol-Triggered Cos And/or H2S Release And Methods Of Making And Using The Same[fr] Composés Pour La Libération De Cos Et/ou De H2S Déclenchée Par Thiol Et Leurs Procédés De Fabrication Et D'Utilisation
标题: Compounds For Thiol-Triggered Cos And/or H2S Release And Methods Of Making And Using The Same[fr] Composés Pour La Libération De Cos Et/ou De H2S Déclenchée Par Thiol Et Leurs Procédés De Fabrication Et D'Utilisation
摘要:本文揭示了一种化合物的实施例,该化合物能够在与含硫醇化合物反应时释放cos和/或h2S.该化合物实施例还可以在释放cos和/或h2S的同时产生可检测的信号(例如,荧光信号),和/或释放活性剂,如治疗剂.还公开了制备和使用该化合物实施例的方法.

专利信息

专利号:EP-4423083-A2
优先权日:2021-11-29
标 题:Synthesis of pyrazolone derivative compounds and their effects on cox enzymes
发明人：ÖNAY UÇAR EVREN; DEM RAYAK EREF; BERK BARKIN; YURTTA LEYLA; B LTEK N KALEL SEVDE NUR; AH N ZAFER
权利人:UNIV ISTANBUL MEDIPOL; ISTANBUL UNIV REKTORLUGU; ANADOLU UNIV
摘要:The invention is related to the synthesis of 8 pyrazolone derivative compounds and their activities on COX enzymes.

专利号:US-8552175-B2
优先权日:2009-04-23
标题:Sulfur transfer reagents for oligonucleotide synthesis
发明人：GUZAEV ANDREI P
权利人:GUZAEV ANDREI P; A M CHEMICALS INC
摘要:The use of N-formamidino-5-amino-3H-1,2,4-dithiazole-3-thiones, 5-phenyl-3H-1,2,4-dithiazole-3-thiones, and derivatives thereof as novel, efficient sulfur-transfer reagents is disclosed. Sulfur transfer from these reagents to compounds containing a P(III) atom (e.g., triphenylphosphine, 5′-O-DMT-thymidine 2-cyanoethyl-(N,N-diisopropyl)phosphoramidite, and 5′-O-DMT-3′-O-levulinyl dithymidilyl 2-cyanoethyl phosphite), was studied in solution by 31 P NMR and HPLC. The sulfur transfer from title compounds was also studied in the solid-phase synthesis of oligonucleotide phosphorothioates by phosphoramidite methods. In this application, the efficiency of the sulfur transfer reaction for 2′-deoxyoligonucleotides was better than 99.5%. The novel sulfurizing agents are synthesized, at low cost, using simple chemical methods. As opposed to many sulfur transfer reagents known in the prior art such as 1,2-benzodithiol-3-one-1,1-dioxide (Beaucage reagent) and 5-ethoxy-3H-1,2,4-dithiazole-2-one (EDIT), the sulfurizing agents disclosed herein are highly stable in solution, which increases their practical and commercial value.

专利号:US-4010173-A
优先权日:1975-02-26
标 题:Synthesis of 4-cyanothiazoles
发明人：HARTMAN GEORGE D; WEINSTOCK LEONARD M
权利人:MERCK & CO INC
摘要:4-Cyanothiazoles are prepared by reacting beta , beta -dichloro- alpha -amino-acrylonitrile with a thioformamide in the presence of an acidic catalyst.

专利号:WO-2023096623-A2
优先权日:2021-11-29
标题:Synthesis of pyrazolone derivative compounds and their effects on cox enzymes

专利号:CN-114990587-A
优先权日:2022-06-30
标题:A kind of electrochemical synthesis method of thiazole compounds

专利号:RU-2059620-C1
优先权日:1988-09-14
标题:Arylpyrrol derivatives, method of their synthesis, intermediate compounds and a method of struggle against insects, nematodes and ticks