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CAS号80287-53-2 3-氨基-6-甲基吡啶 | CAS号113209-90-8 4-氯-5-氟-2-吡啶甲醇 | CAS号107504-08-5 5-氟吡啶-2-羧酸 | CAS号113209-88-4 2-甲基-4-硝基-5-氟吡啶... | CAS号45673-79-8 5-氟-2-甲基-4-硝基-1...专利信息
专利号:US-8344118-B2
优先权日:2007-10-31
标 题 :Preparation and isolation of 5′ capped MRNA
发明人:KORE ANILKUMAR; MUTHIAN SHANMUGASUNDARAM; CHARLES IRUDAYA
权利人:APPLIED BIOSYSTEMS LLC; KORE ANILKUMAR; MUTHIAN SHANMUGASUNDARAM; CHARLES IRUDAYA
摘要:The synthesis of capped/tagged RNA, methods of use and kits providing same are contemplated. Tagged RNA permits isolation of RNA transcripts in vitro. The ability to isolate and purify capped RNA results in improved transcription and translation and provides a tool for identifying RNA-protein interactions. Such capped RNA finds use in therapeutic applications, diagnosis and prognosis and in the treatment of cancers and HIV.
专利号:US-6803461-B2
优先权日:2002-01-04
标 题 :Synthesis of ceftiofur intermediate
发明人:DESHPANDE PRAMOD NARAYAN; KHADANGALE BHAUSAHEB PANDHARIN; KUMAR SURULICHAMY SENTHIL; DAS GAUTAM KUMAR
权利人:ORCHID CHEMICALS & PHARM LTD
摘要:The present invention relates to a process for preparation of 7-amino-3-[2-(furylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid (I) by the condensation of 7-aminocephalosporanic acid (II) with furyl-2-carbonylthiol (III) in the presence of borontrifluoride or its complex, in an organic solvent or mixture of solvents at 0-50° C.
专利号:US-11332564-B2
优先权日:2020-03-19
标 题:Method to produce stimuli sensitive UV absorbing polymers
发明人:KOSHTI NIRMAL; KURAKULA THULASIRAMREDDY PRABHU CHARAN
权利人:GALAXY SURFACTANTS LTD
摘要:Eco-friendly aqueous synthesis of substantive, UV-absorbing, cationic polymers with ‘inverse temperature dependent solubility’ are described in the present invention. These polymers are water-soluble at ambient temperature and water-resistant at temperature of human body as well as in the presence of electrolytes. This property makes these polymers useful for personal care products that are designed for protecting skin and hair from damages of UV radiation. n The invention relates to aqueous synthesis of polymers of Formula I wherein, ArCO is an UV absorbing moiety selected from 2-cyano-3,3-diphenyl acryloyl, and p-methoxy cinnamoyl, R 1 is selected from H and C 1 -C 3 alkyl group, and R 2 is selected from C 1 -C 3 alkyl group, m and n are integers and a ratio of m to n is 40:5 to 40:1.
专利号:US-2003130502-A1
优先权日:2002-01-04
标 题:Synthesis of ceftiofur intermediate
专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.
专利号:WO-2023114200-A2
优先权日:2021-12-14
标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof