CAS: 4668-42-2; (S)-3-(((Benzyloxy)Carbonyl)Amino)-4-Methoxy-4-Oxobutanoic Acid

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上下游产品

CAS号67-56-1 甲醇 | CAS号4515-23-5 Z-天冬氨酸酸酐 | CAS号4668-37-5 ZL-天冬酰胺甲酯 | CAS号1152-61-0 N-CBZ-L-天冬氨酸 | CAS号57933-83-2 异丙烯基氯甲酸酯 | CAS号79-22-1 氯甲酸甲酯 | CAS号124-41-4 甲醇钠 | CAS号23632-66-8 (S)-(+)-3(苄氧羰基)... | CAS号63327-57-1 ZL-天冬氨酸β-叔丁酯α-甲基酯 | CAS号15545-10-5 Z-L-组氨酸甲酯 | CAS号5545-52-8 N-苄氧羰基-L-天门冬氨酸 4-叔丁酯 | CAS号17812-32-7 L-天门冬氨酸 1-甲酯 | CAS号21149-17-7 N-Cbz-脱氢丙氨酸甲酯 | CAS号63327-57-1 ZL-天冬氨酸β-叔丁酯α-甲基酯 | CAS号39895-10-8 H-Asp(OtBu)-OMe

(S)-N-Benzyloxycarbonyl-L-Tryptophan Methyl Ester置于ruthenium Trichloride,Sodium Periodate体系中,用 四氯化碳,水,乙腈 作为反应溶剂,化学反应 60.0H,以65%的收率获得产物n-Cbz-L-天冬氨酸 1-甲酯
参考文献:肽中色氨酸向天冬氨酸的转化
标题:肽中色氨酸向天冬氨酸的转化
摘要:色氨酸侧链通过原位反应生成的钌(viii)以高收率转化为天冬氨酸.根据四氢咔唑向己二酸,缬氨酸向异丁酸,苯丙氨酸向苯乙酸的转化,提出了多步降解顺序.
DOI:10.1039/c39870001085

专利信息

专利号:US-9499472-B2
优先权日:2012-03-05
标题:Aspartylamide inhibitors of excitatory amino acid transporters
发明人：GERDES JOHN M; BRIDGES RICHARD J; AHMED SYED K; PATEL SARJUBHAI
权利人:THE UNIV OF MONTANA
摘要:The compounds of the invention are inhibitors of excitatory amino acid transporters (EAAT) that penetrate the blood-brain barrier to access the central nervous system. The compounds of the invention follow the structural formula: n nor a salt, ester or prodrug thereof, wherein X is a halogen, such as fluorine, or a radionuclide, such as fluorine-18. The compounds and methods described herein can be used for the treatment of, e.g., neurodegenerative disorders (e.g., amyotrophic lateral sclerosis), ischemia, spinal cord injury, and traumatic brain injury in a patient (e.g., a human). The invention further provides compounds and methods for the synthesis and use of radiographic tracers to diagnose and follow the progression of such disorders.

专利号:WO-2024097744-A2
优先权日:2022-11-01
标题 :Dna-compatible wittig olefination of on-dna peptidyl-ylides for development of on-dna peptidomimetics through diversity-oriented synthesis (dos)

专利号:WO-9012883-A1
优先权日:1989-04-24
标题:Enzymatic membrane method for the synthesis and separation of peptides