CAS: 504-60-9; Trans-1,3-Pentadiene

上下游产品

CAS号1569-50-2 3-戊烯-2-醇 | CAS号71-41-0 正戊醇 | CAS号96-47-9 2-甲基四氢呋喃 | CAS号626-95-9 1,4-戊二醇 | CAS号616-25-1 1-戊烯-3-醇 | CAS号67-51-6 3,5-二甲基吡唑 | CAS号675-10-5 6-甲基-4-羟基-2-吡喃酮 | CAS号591-93-5 1,4-戊二烯 | CAS号109704-11-2 2-prop-1-enyl-3... | CAS号1459-05-8 1-methyl-3-(4-p... | CAS号1458-99-7 4-chloropent-2-ene | CAS号18476-56-7 4-methylnona-2,... | CAS号20459-96-5 methyl 2-methyl... | CAS号13894-62-7 methyl (Z)-3-he... | CAS号2258-55-1 2-Methyl-cis-3-... | CAS号1809-26-3 4-bromo-2-pentene | CAS号111-27-3 正己醇 | CAS号74-84-0 乙烷

戊烷-1,3-二醇置于h3Siw12O40/sba体系中,用 二氯甲烷 作为反应溶剂,以76%的收率获得产物间戊二烯
参考文献:一种基于醛酮缩合反应合成二烯烃类化合物的方法
标题:一种基于醛酮缩合反应合成二烯烃类化合物的方法
摘要:本发明提供了一种基于醛酮缩合反应合成二烯烃类化合物的方法,包括以下步骤,首先在缩合催化剂的作用下,将酮类化合物和醛类化合物进行缩合反应后,得到缩合产物;然后在还原催化剂的作用下,将上述步骤得到的缩合产物进行还原反应后,得到还原产物;在催化剂的作用下,将上述步骤得到的还原产物进行脱水反应后,得到二烯烃类化合物.本发明可利用廉价易得的酮,醛及其同系物为原料,合成丁二烯,间戊二烯及其同系物等二烯烃类化合物,实验条件温和,操作简单,具有规模化合成的前景.

专利信息

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-10450201-B2
优先权日:2017-10-04
标题 :Method for the synthesis of nanoparticles of heterometallic nanocomposite materials
发明人：SOHAIL MANZAR; SHARIF MUHAMMAD; KHAN SAFYAN A; SHER MUHAMMAD; JAGADEESH RAJENAHALLY V
权利人:UNIV KING FAHD PET & MINERALS
摘要:A simple one pot sol-gel method for the synthesis of bi-metal nanostructures is based on non-noble metals (Fe, Co and Sn) and titanium. The method involves the synthesis of mixed metal nanoscale composites using low cost precursors which allow for the synthesis of desired nanocomposite materials with self-scarifying titanium or silica supports. The procedure does not require any surfactant or any need for pH controlled step. Applicants' method involves the in-situ generation of precursors and their simultaneous entrapment in a gel. This simple one pot synthesis allows for the synthesis of homogenous size, shape and distribution of targeted nanostructures. Further, this method can be applied for the preparation of various nanocomposite materials using different choices of metals and self-scarifying supports. Applicants also show that Pd, the noble metal based nanocomposite is feasible.

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.

专利号:US-2012302756-A1
优先权日:2010-02-19
标 题 :Process for synthesis of 2-substituted pyrrolidines and piperadines
发明人：LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
权利人:LELETI RAJENDER REDDY; LIU YUGANG; PRASHAD MAHAVIR
摘要:The present invention provides a highly efficient, versatile one-step process for asymmetric synthesis of either diastereomer of 2-substituted pyrrolidines from a single starting material with excellent yields and high diastereoselectivety. Also provided is a method for the asymmetric synthesis of both diastereomers of 2-substituted piperidines with good yields and excellent diastereoselectivety. Diasteroselectivity is controlled effectively by choice of reducing agent.

专利号:WO-2012047907-A9
优先权日:2010-10-04
标题 :Synthesis of c5-substituted tetracyclines, uses thereof, and intermediates thereto
发明人：MYERS ANDREW G; WRIGHT PETER M; HECKER EVAN
权利人:HARVARD COLLEGE; MYERS ANDREW G; WRIGHT PETER M; HECKER EVAN
摘要:The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides more efficient routes for preparing the enone intermediate and allows for a wide variety of substituents at position 5 of the tetracycline ring system.