CAS: 870-50-8; Di-Tert-Butyl Diazene-1,2-Dicarboxylate

相似化合物

1972-28-7 2446-83-5 2449-05-0

上下游产品

CAS号16466-61-8 二叔丁基叠氮草酸 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号28899-97-0 bis(acetato-O)t... | CAS号345310-98-7 1-(2-吡啶基)-哌嗪酮 | CAS号16466-61-8 二叔丁基叠氮草酸 | CAS号185456-26-2 1,1,2-三羧酸三叔丁基肼 | CAS号13051-19-9 3,6-二氢-1,2-哒嗪二羧酸二叔丁酯 | CAS号13051-18-8 2,3-Diazabicycl... | CAS号65578-58-7 tert-butyl N-[(... | CAS号65813-90-3 Tetrathiobernst...

叔-丁基氯甲酸酯置于吡啶,溴,肼体系中,用 乙醇,二氯甲烷,水 作为反应溶剂,化学反应 2.0H,反应生成 偶氮二甲酸二叔丁酯
参考文献:黄素和可见光介导的mitsunobu反应条件下的光催化酯化†
标题:黄素和可见光介导的mitsunobu反应条件下的光催化酯化†
摘要:证明了基于黄素的空中光氧化在mitsunobu反应条件下进行酯化反应中的有用性,从而提供了从相应的二烷基肼二羧酸二乙酯中回收/反应生成空中二烷基偶氮二羧酸酯的方法.同时,通过黄素的光诱导电子转移激活三苯膦(ph 3 P)可以使无偶氮试剂进行酯化.已显示使用3-乙酸甲基黄酮黄素四乙酸酯(10%),氧气(末端氧化剂),可见光(450 Nm),Ph 3 P和二羧酸肼二甲酸二烷基酯(10%)的优化系统可提供各种醇的高效立体选择性偶联和酸变成酯,并保留构型.
DOI:10.1039/c6Ob02770A

专利信息

专利号:WO-2015193910-A1
优先权日:2014-06-20
标题:Asymmetric synthesis of 2-substituted indolines and 3-substituted cinnolines
发明人：KUMAR BOOPATHY SENTHIL; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to a novel one step proline catalyzed process for synthesis of chiral hydrazine and its derivatives from o-bromo hydro cinamaldehyde. Further, it relates to a novel one step process for the synthesis of substitued indolines and cinnolines from chiral hydrazines and its derivatives.

专利号:US-7691968-B2
优先权日:2002-05-03
标题:Process for the synthesis of peptides amides by side-chain attachment to a solid phase
发明人：EVANS DAVID JOHN; SIMPKIN DEAN STEVEN ANTHONY; WELLINGS DONALD ALFRED; ATHERTON ERIC
权利人:AVECIA BIOLOG LTD
摘要:A process is provided for the solid-phase synthesis of a peptide amide which comprises attaching an α-nitrogen protected Cα-carboxamide amino acid to a solid support by its side chain, removing the α-nitrogen protecting group, assembling a peptide chain on said α-nitrogen and then cleaving the assembled peptide amide from the solid support. Novel amino acid analogues, peptide amides and solid-phase supports are also provided.

专利号:US-2024368164-A1
优先权日:2021-04-28
标 题 :Purine nucleosides, their intermediates, and methods of preparation thereof
发明人：RAVI RAMA SURESH; JACOBSON KENNETH A; POE RUSSELL BIRCH
权利人:ASTROCYLE PHARMACEUTICALS INC; US HEALTH
摘要:The present invention provides purine nucleoside analog compounds and methods of use thereof for treatment of certain injuries, disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries. The present invention further provides methods of synthesizing such compounds, and intermediates useful in the synthesis of such compounds.

专利号:US-2024309003-A1
优先权日:2021-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN; PANDYA BHAUMIK; KAPLAN ALAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-9403864-B2
优先权日:2010-05-31
标题:Process for the synthesis of carbonucleoside and intermediates for use therein
发明人：ALBERICO DINO; CLAYTON JOSHUA; DIXON CRAIG; GORIN BORIS
权利人:ALBERICO DINO; CLAYTON JOSHUA; DIXON CRAIG; GORIN BORIS; ALPHORA RES INC
摘要:Disclosed is a process for preparing a carbonucleoside of formula (1) and intermediates for use therein. The process involves the step of reacting a compound of formula (2) with a compound of formula (3) under Mitsunobu-type reaction conditions to obtain a compound of formula (4), wherein PG 1 , PG 2 , PG 3 and PG 4 are protecting groups. The compound of formula (4) is deprotected to form the compound of formula (1), as shown below.

专利号:US-2012095211-A1
优先权日:2010-09-22
标 题 :Substituted proline inhibitors of hepatitis c virus replication
发明人：BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D
权利人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D; INTERMUNE INC
摘要:The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IIIb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. The embodiments also provide methods for the synthesis of subject compounds and intermediates in the synthetic methods.