CAS: 3054-01-1; H-Cys(Bzl)-Oh

该化合物是探索与氧化性压力和细胞信号有关的行动机制.与许多氨基酸衍生物一样,S-Benzyl-L-cysteine的稳定性和再活动性等环境因素会影响环境反应,例如:Penzyl-L-cysteine的稳定性和再活动.

结构式图片

相似化合物

5068-28-0 53298-33-2 102830-49-9

上下游产品

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合成工艺路线路线简述

    L-胱氨酸置于氨,Sodium体系中,化学反应生成 S-苄基-L-半胱氨酸
    参考文献:Wood; Du Vigneaud,Journal Of Biological Chemistry,1939,Vol. 130,P. 109,111
    标题:Wood; Du Vigneaud,Journal Of Biological Chemistry,1939,Vol. 130,P. 109,111

    海关参考信息

    专利信息


    专利号:US-7459443-B2
    优先权日:1999-04-08
    标 题 :Synthesis of biologically active compounds in cells
    发明人:SERGEEV PAVEL
    权利人:SERGEEV PAVEL
    摘要:This invention relates to a new method of synthesis of biologically active substances of determined structure directly in the cells of living organisms containing specific RNA or DNA molecules of determined sequence. The method is based on the hybridization of two or more oligomers bound with biologically inactive precursors of biologically active substances to specific RNA or DNA in vivo in the cells of living organisms. After hybridization of the oligomers to RNA or DNA the biologically inactive precursors bound to the 5′ and/or 3′ ends of the oligomers can interact with each other to make biologically active form of the substances. This changing of properties is due to chemical reactions which bind the biologically inactive precursors through a chemical bond into a biologically active form of the whole compound.

    专利号:US-2022098155-A1
    优先权日:2018-11-14
    标 题 :Novel pathway for the synthesis of diazirines, that may or may not be enriched in nitrogen-15
    发明人:REBOUL VINCENT; FRANCK XAVIER; GLACHET THOMAS; MARZAG HAMID
    权利人:UNIV ROUEN NORMANDIE; UNIV CAEN; INSTITUT NAT DES SCIENCES APPLIQUEES DE ROUEN INSA; CENTRE NAT RECH SCIENT; ECOLE NAT SUPERIEURE DINGENIEURS DE CAEN
    摘要:The present invention concerns a novel method for synthesising diazirines, that may or may not be enriched in nitro-gen-15, from amino acids or imines, via a one-pot synthesis method, comprising the reaction of the starting amino acid or imine with ammonia, which may or may not be enriched in nitrogen-15, and a hypervalent iodine oxidant. The present invention also relates to a method for synthesising ammonia enriched in nitrogen-15. The invention also concerns certain diazirines of formula (I) likely to be obtained by the claimed synthesis method, and also refers to the 15 N 2 -diazirines of formula (I′). The claimed diazirines can be used in photoaffinity labelling. The 15 N 2 -diazirines can also be used in hyperpolarisation, in particular in the medical imaging field.

    专利号:US-5990273-A
    优先权日:1993-06-29
    标 题:Synthesis of cyclic peptides
    发明人:ANDERSSON LARS HENRIK HARALD; SKOLDBACK JAN-AKE
    权利人:FERRING BV
    摘要:A process for preparing and purifying cyclic peptides having disulfide moieties in a two step processing operation including reverse phase chromatography which simplifies synthesis and reduces production costs, yet produces high, quality yield. The improved process is particularly useful for the preparation of vasopressin and oxytocin and their respective derivatives and analogs.

    专利号:US-4033940-A
    优先权日:1975-11-12
    标 题:Cyclization of peptides
    发明人:HUGHES JOHN L; SEYLER JAY K; LIU ROBERT C
    权利人:ARMOUR PHARMA
    摘要:The synthesis of a disulfide cyclic peptide by preparing an intermediate peptide containing an amino terminal cystine residue and a cysteine residue located in a position within the amino acid sequence, to give a desired peptide, and placing such intermediate peptide in a solution substantially free of oxygen at a pH of from about 5 to 10 until rearrangement takes place to yield a cyclic disulfide peptide and to displace a molecule of cysteine from the amino terminal cysteine residue. The disclosure also embraces said intermediate peptides as new compounds and the processes by which they are prepared.

    专利号:US-11970551-B2
    优先权日:2018-08-20
    标题 :Solution phase routes for WNT hexapeptides
    发明人:HENRIKSEN DENNIS
    权利人:WNTRESEARCH AB
    摘要:The present disclosure relates generally to the field of polypeptide synthesis, and more particularly, to the solution phase synthesis of the Wnt hexapeptide Foxy-5 and protected derivatives and peptide fragments thereof.

    专利号:US-4950418-A
    优先权日:1986-10-09
    标题 :Reagent for removing protective groups in peptide synthesis
    发明人:YAJIMA HARUAKI; FUJII NOBUTAKA; GUTERRES GILBERTO M A; HONGUU TATSUHIKO
    权利人:SHINETSU CHEMICAL CO
    摘要:Reagent for removing protective groups employed in peptide synthesis comprises a combination of hard acid and soft base. The hard acid is trialkylsilyltrifluoromethanesulphonate R3SiO3SCF3 and the soft base is ether. The reagent provides high efficiency of deprotection and has a low tendency to cause side reaction.
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    合成参考文献


    摘要:Compound: Poly(S-benzyl-L-cysteine)
    参考文献:10.1074/jbc.m800730200
    摘要:Emter R, Natsch A. The Sequential Action of a Dipeptidase and a β-Lyase Is Required for the Release of the Human Body Odorant 3-Methyl-3-sulfanylhexan-1-ol from a Secreted Cys-Gly-(S) Conjugate by Corynebacteria. Journal of Biological Chemistry. 2008 Jul;283(30):20645–52. doi: 10.1074/jbc.m800730200.
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