CAS: 5617-74-3; 3-Oxabicyclo[3.1.0]Hexane-2,4-Dione

相似化合物

67911-21-1 187681-87-4 696-16-2

上下游产品

CAS号1489-58-3 环丙烷-1,2-二羧酸 | CAS号702-90-9 cyclopropane-1,... | CAS号7605-64-3 tetraethyl cycl... | CAS号58616-95-8 反式 环丙烷-1,2-二羧酸 | CAS号7605-65-4 cyclopropane-1,... | CAS号878-14-8 Aethylmethyl-1,... | CAS号20561-09-5 环丙烷-1,2-二羧酸二乙酯 | CAS号696-74-2 (1R,2S)-rel-环丙烷... | CAS号710-43-0 顺式-环丙烷-1,2-二羧酸二乙酯 | CAS号111887-60-6 3-hydroxy-3-aza... | CAS号826-34-6 顺-1,2-环丙烷二羧酸二甲酯 | CAS号710-43-0 顺式-环丙烷-1,2-二羧酸二乙酯 | CAS号70110-45-1 3-苄基-3-氮杂双环[3.1.0]己烷 | CAS号73799-63-0 3-苯甲基-3-氮杂二环[3.... | CAS号13279-88-4 2-(甲氧羰基)环丙基甲酸 | CAS号1601-81-6 Cyclopropanecar... | CAS号279692-23-8 4-(4,4-二甲基-2,6-... | CAS号696-74-2 (1R,2S)-rel-环丙烷...

环丙烷-1,1,2-三羧酸 反应生成 3-氧杂二环[3.1.0]己烷-2,4-二酮
参考文献:Fichter; Spiegelberg,Helvetica Chimica Acta,1929,Vol. 12,P. 1153
标题:Fichter; Spiegelberg,Helvetica Chimica Acta,1929,Vol. 12,P. 1153

专利信息

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:US-10793557-B2
优先权日:2018-04-03
标题 :Sting agonist compounds
发明人：ALTMAN MICHAEL D; CASH BRANDON D; CHILDERS MATTHEW LLOYD; CUMMING JARED N; DEMONG DUANE E; HAIDLE ANDREW MARC; HENDERSON TIMOTHY J; JEWELL JAMES P; LARSEN MATTHEW A; LIM JONGWON; LU MIN; OTTE RYAN D; TROTTER BENJAMIN WESLEY
权利人:MERCK SHARP & DOHME
摘要:Compounds of general formula (I), of general formula (II), of general formula (III), of general formula (IV), of general formula (V), of general formula (VI), and their pharmaceutically acceptable salts, wherein all variables are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are compositions comprising such compounds, processes for the synthesis of such compounds, and to uses of such compounds, including administration of such compounds to induce immune response, to induce STING-dependent type I interferon production, and/or to treat a cell proliferation disorder, such as cancer.

专利号:US-11702430-B2
优先权日:2018-04-03
标 题:Aza-benzothiophene compounds as STING agonists
发明人：ALTMAN MICHAEL D; CASH BRANDON D; CUMMING JARED N; DEMONG DUANE E; HAIDLE ANDREW M; JEWELL JAMES P; LARSEN MATTHEW A; LU MIN; OTTE RYAN D; TAOKA BRANDON M; TROTTER BENJAMIN WESLEY; TRUONG QUANG T
权利人:MERCK SHARP & DOHME LLC; ALTMAN MICHAEL D; CASH BRANDON D; CUMMING JARED N; DEMONG DUANE E; HAIDLE ANDREW M; JEWELL JAMES P; LARSEN MATTHEW A; LU MIN; OTTE RYAN D; TAOKA BRANDON M; TROTTER BENJAMIN WESLEY; TRUONG QUANG T
摘要:Compounds of general formula (I), and their pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 , R 5 , R 6 , R 8 , R 9 , A, X 1 , X 2 , and X 3 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are compositions comprising such compounds, processes for the synthesis of such compounds, and to uses of such compounds, including administration of such compounds to induce immune response, to induce STING-dependent type I interferon production, and/or to treat a cell proliferation disorder, such as cancer.

专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.

专利号:CN-118878805-A
优先权日:2024-08-19
标 题:Composite zinc dicarboxylic acid catalyst and application thereof in catalytic synthesis of carbon dioxide-based polycarbonate

专利号:US-2024116909-A1
优先权日:2021-01-12
标题 :Novel compounds useful as sting agonists and uses thereof
发明人：YE YANG; LI XIUWEI; YANG GUIQUN; YAN FASHUN; WANG YANPING; LONG WEI
权利人:JACOBIO PHARMACEUTICALS CO LTD
摘要:Compounds of general Formula I, II, III, IV, V and their pharmaceutically acceptable salts, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are synthesis, compositions, and uses of such compounds.