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CAS号2634-33-5 1,2-苯并异噻唑啉-3-酮 | CAS号132636-65-8 3-(4-nitropheno... | CAS号132636-61-4 3-naphthalen-1-... | CAS号59777-72-9 2-甲酸乙酯苯磺酰胺 | CAS号109538-88-7 2-[(4-nitrophen... | CAS号105338-19-0 2-cyclohex-2-en... | CAS号107915-69-5 2-(4-methoxyben... | CAS号35812-01-2 N-溴邻磺酰苯酰亚胺 | CAS号35511-14-9 4-羟基-2H-1,2-苯并噻... | CAS号57683-71-3 邻甲酸甲酯苯磺酰胺 | CAS号34042-85-8 Sudoxicam | CAS号35511-15-0 4-羟基-2-甲基-2H-1,... | CAS号55-21-0 苯甲酰胺 | CAS号942047-62-3 Methyl 4-hydrox...合成工艺路线路线简述
- 34684-21-4 = 81-07-2
反应条件:1.1 Reagents: Ammonium Hydroxide Solvents: Water
标题:Further Investigations On The Two Isomeric Chlorides Of Orthosulphobenzoic Acid
作者:Remsen,Ira
参考文献:American Chemical Journal 日期:1903 卷标:30 页码:247-309]
80283-99-4 = 81-07-2
反应条件:1.1 Reagents: Water Solvents: Water
标题:Chemistry Of Nitroimides. 2. Hydrolysis And Alcoholysis Of Nitroimides
作者:Kozlova,I. K.; Et Al
参考文献:Izvestiya Akademii Nauk Sssr 日期:1981 卷标:(11) 页码:2556-63]
= 81-07-2
反应条件:1.1 Reagents: Pyrrolidine Solvents: Acetonitrile; 1 H,20 °C
标题:Tosvinyl And Besvinyl As Protecting Groups Of Imides,Azinones,Nucleosides,Sultams,And Lactams. Catalytic Conjugate Additions To Tosylacetylene
作者:Petit,Elena; Et Al
参考文献:Journal Of Organic Chemistry 日期:2014 卷标:79(18) 页码:8826-8834]
88-19-7 = 81-07-2
反应条件:1.1 Reagents: Chromium Sulfate
标题:Electrochemistry Of Drug Manufacture. Ii. 2
作者:Mizuguchi,Jun
参考文献:Yakugaku Zasshi 日期:1947 卷标:67 页码:94-7]
88-19-7 = 81-07-2
反应条件:1.1 Reagents: Periodic Acid (H5Io6) Catalysts: Chromium Trioxide Solvents: Acetonitrile; Rt -> 85 °C; 1 H,85 °C
标题:Oxidative Cyclization Of N-Alkyl-O-Methyl-Arenesulfonamides To Biologically Important Saccharin Derivatives
作者:Xu,Liang; Et Al
参考文献:Tetrahedron 日期:2006 卷标:62(33) 页码:7902-7910]
59777-72-9 = 81-07-2
反应条件:1.1 Solvents: 1,1,2,2-Tetrachloroethane; 10 Min,50 °C1.2 Catalysts: Titanium Tetrachloride; 48 H,115 °C
标题:Ticl4-Promoted Direct N-Acylation Of Sulfonamide With Carboxylic Ester
作者:Fu,Shaomin; Et Al
参考文献:Tetrahedron Letters 日期:2010 卷标:51(44) 页码:5834-5837]
15448-99-4 = 81-07-2
反应条件:1.1 Reagents: Lithium Perchlorate Solvents: Methanol,Acetonitrile; 25 °C
标题:Electrically-Driven N(Sp2)-C(Sp2/3) Bond Cleavage Of Sulfonamides
作者:Wetzel,Annica; Et Al
参考文献:Acs Sustainable Chemistry & Engineering 日期:2020 卷标:8(8) 页码:3487-3493]
128-44-9 = 81-07-2
反应条件:1.1 Reagents: Trichloromethylsilane Solvents: Acetone; Rt; Rt -> 56 °C; 24 H,56 °C
标题:Synthesis Study Of Saccharin-Methyl-Chlorosilane
作者:Li,Xin; Et Al
参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2010 卷标:18(4) 页码:29-31]
1260436-07-4 = 81-07-2
反应条件:1.1 Solvents: Acetonitrile; 37 H,Rt
标题:Studies Of Silyl-Transfer Photochemical Reactions Of N-[(Trimethylsilyl)Alkyl]Saccharins
作者:Cho,Dae Won; Et Al
参考文献:Bulletin Of The Korean Chemical Society 日期:2010 卷标:31(9) 页码:2453-2458]
127872-18-8 = 81-07-2
反应条件:1.1 Reagents: Trifluoroacetic Acid Solvents: Trifluoroacetic Acid
标题:Tilcotil Studies. Part 2. [4 + 2] Additions With Isothiazol-3(2H)-One 1,1-Dioxide
作者:Burri,Kaspar F.
参考文献:Helvetica Chimica Acta 日期:1990 卷标:73(1) 页码:69-80]
91387-28-9 = 81-07-2
反应条件:1.1 Reagents: Hydrochloric Acid
标题:Synthesis Of N,N'-Bis(Imido)Dialkyltin
作者:Shcherbakov,V. I.; Et Al
参考文献:Zhurnal Obshchei Khimii 日期:1984 卷标:54(9) 页码:2062-4]
57683-71-3 = 81-07-2
反应条件:1.1 Reagents: Hydrochloric Acid; 12 H,Rt
标题:Synthesis,Characterization And Antimicrobial Evaluation Of New 3-(Alkyl/arylamino)Benzo[d]Isothiazole 1,1-Derivatives
作者:Kamble,Dhanraj P.; Et Al
参考文献:Oriental Journal Of Chemistry 日期:2021 卷标:37(4) 页码:797-804]
= 81-07-2 [标题:Reaction Conditions
标题:Reactions With Pseudosaccharin Chloride. Iii. Novel Fragmentation Reaction Leading To Multiple Bond Formation
作者:Hettler,Hans; Et Al
参考文献:Tetrahedron Letters 日期:1966 卷标:(48) 页码:6031-5]
34684-21-4 = 81-07-2
反应条件:1.1 Reagents: Ammonia Solvents: Tert-Butanol
标题:Sulfobenzoic Acid Esters. Iii. Correct Structures Of The Aryl Esters
作者:Loev,Bernard; Et Al
参考文献:Journal Of Organic Chemistry 日期:1962 卷标:27 页码:2448-52]
1627592-50-0 = 81-07-2
反应条件:1.1 Reagents: Sodium Dodecylthiolate Solvents: Acetonitrile; 0.5 H,20 °C1.2 Reagents: Hydrochloric Acid,Water; Neutralized
标题:Tosvinyl And Besvinyl As Protecting Groups Of Imides,Azinones,Nucleosides,Sultams,And Lactams. Catalytic Conjugate Additions To Tosylacetylene
作者:Petit,Elena; Et Al
参考文献:Journal Of Organic Chemistry 日期:2014 卷标:79(18) 页码:8826-8834]
88-19-7 = 81-07-2
反应条件:1.1 Reagents: Oxygen Catalysts: Cobalt Diacetate,Manganese Diacetate,Sodium Bromide,Zirconium Oxychloride Solvents: Acetic Anhydride
标题:O-Toluenesulfonamide Catalytic Oxidation In The Liquid Phase. I. Synthesis Of 3-Oxo-2,3-Dihydrobenz[d]Isothiazole 1,1-Dioxide (Saccharin) From O-Toluenesulfonamide
作者:Ioffe,E. A.; Et Al
参考文献:Latvijas Psr Zinatnu Akademijas Vestis 日期:1990 卷标:(5) 页码:613-16]
5669-05-6 = 81-07-2
反应条件:1.1 Reagents: Potassium Tert-Butoxide,Oxygen,1H-Imidazolium,3-Ethyl-1-Methyl-,Tetrafluoroborate(1-) (9:10) Solvents: 1,4-Dioxane; 3 H,Rt
标题:From Imines To Amides Via Nhc-Mediated Oxidation
作者:Sun,Shaofa; Et Al
参考文献:Organic Chemistry Frontiers 日期:2022 卷标:9(2) 页码:356-363
2-Sulfo-Benzoic Acid ; Ammonium Salt 反应生成 糖精
参考文献:Taeufel; Naton,Angewandte Chemie,1926,Vol. 39,P. 225
标题:Taeufel; Naton,Angewandte Chemie,1926,Vol. 39,P. 225
专利信息
专利号:US-2023287032-A1
优先权日:2020-08-14
标 题:Synthesis of fluorinated nucleotides
发明人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO
权利人:CHUNG CHEOL KEUN; LIU ZHIJIAN; MALIGRES PETER E; MAO EDNA; OBLIGACION JENNIFER V; PHILLIPS ERIC M; PIRNOT MICHAEL; POIRIER MARC; SONG ZHIGUO JAKE; WANG TAO; MERCK SHARP & DOHME LLC
摘要:The present invention relates to efficient processes useful in the preparation of fluorinated nucleosides, such as (O—{[(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl}O,O-dihydrogen phosphorothioate, also known as 2′-(S)-fluoro-thio-adenosine monophosphate or 2′-F-thio-AMP. Such fluorinated nucleosides may be useful as a biologically active compound and or as an intermediate for the synthesis of more complex biologically active compounds. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.
专利号:WO-2023095077-A1
优先权日:2021-11-26
标题 :A process for the treatment of tail gases
发明人:LODHA DHANANJAY MAHENDRA
权利人:SHREE SULPHURICS PVT LTD
摘要:The present disclosure relates to a process for the treatment of tail gases. The process of the present disclosure is simple and environmentally friendly. The process of the present disclosure produces chlorosulfonic acid, which is a value-added reagent used in the synthesis of alkyl sulphates detergents, saccharin and the like. Further, the process of the present disclosure produces sulfuryl chloride, which is an important value added chlorinating agent in the organic synthesis/reactions.
专利号:US-4042600-A
优先权日:1972-10-17
标 题 :Pyrolysis of 2-sulfochloride benzoates
发明人:DIPIPPO CARMINE A
权利人:SCOTT PAPER CO
摘要:Ortho-sulfobenzoic anhydride is synthesized by pyrolysis of the 2-sulfochloride benzoates. The benzoate intermediates are readily prepared by reacting either the esters of dithiodibenzoic acid with chloride water or the 2-diazonium chloride benzoates with sulfur dioxide. The invention also provides for the total synthesis of saccharin, free of bitter tasting contaminants, from such reactants, the ultimate step in such synthesis being the ammonolysis of the o-sulfobenzoic anhydride.
专利号:US-8093397-B2
优先权日:2001-07-03
标 题:Activators for oligonucleotide synthesis
发明人:SINHA NANDA; ZEDALIS WILLIAM EDWARD; MIRANDA GREGORY KEITH
权利人:SINHA NANDA; ZEDALIS WILLIAM EDWARD; MIRANDA GREGORY KEITH; AVECIA BIOTECHNOLOGY INC
摘要:A process for the synthesis of oligonucleotides using phosphoramidite chemistry is provided. The process employs as activator a 1,1-dioxo-1,2-dihydro-1λ6-benzo[d]isothiazol-3-one, preferably in the presence of an organic base. The 1,1-dioxo-1,2-dihydro-1λ6-benzo[d]isothiazol-3-one is represented by the following structural formula: wherein p is 0 or an integer from 1 to 4; X7 is O or S; R for each occurrence is a substituent, preferably each independently, a halo, a substituted or unsubstituted aliphatic group, —NR11R12, —OR13, —OC(O)R13, —C(O)OR13, or cyano; or two adjacent R groups taken together with the carbon atoms to which they are attached form a six membered saturated or unsaturated ring; R11 and R12 are each, independently, —H, a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aralkyl group; and R13 is a substituted or unsubstituted aliphatic group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aralkyl group. Preferred organic bases are pyridine, 3-methylpyridine, or N-methylimidazole.
专利号:US-2017204442-A1
优先权日:2014-05-29
标题 :Enzymatic synthesis of soluble glucan fiber
发明人:DICOSIMO ROBERT; CHENG QIONG; ELIOT ANDREW C; OUWEHAND ARTHUR; PAYNE MARK S; YOU ZHENG
权利人:DU PONT
摘要:An enzymatically produced soluble α-glucan fiber composition is provided suitable for use as a digestion resistant fiber in food and feed applications. The soluble α-glucan fiber composition can be blended with one or more additional food ingredients to produce fiber-containing compositions. Methods for the production and use of compositions comprising the soluble α-glucan fiber are also provided.
专利号:US-2024308959-A1
优先权日:2021-06-29
标 题:Processes for the preparation of (s)-2-(4-chloro-2-methoxyphenyl)-2-((3 -methoxy-5-(m ethylsulfonyl)phenyl)amino)-1 -(1h-indol-3-yl)ethenone derivatives
发明人:WU KAI; OOST RIK; SCHWEITZER-CHAPUT BERTRAND; ERIKSSON CARL ARNE MAGNUS; COESEMANS ERWIN
权利人:JANSSEN PHARMACEUTICALS INC
摘要:The present invention relates to novel chiral synthesis of mono- or di-substituted indole compounds of formula (I) n n n n n n n n n n n n wherein: n R 1 is H, R 2 is F and R 3 is H or CH 3 , n R 1 is H, CH 3 or F, R 2 is OCH 3 and R 3 is H and n R 1 is H, R 2 is OCH 3 and R 3 is CH 3 , n R 1 is CH 3 , R 2 is F and R 3 is H, n R 1 is CF 3 or OCF 3 , R 2 is H and R 3 is H, n R 1 is OCF 3 , R 2 is OCH 3 and R 3 is H and n R 1 is OCF 3 , R 2 is H and R 3 is CH 3 .