CAS: 2065-23-8; Methyl 2-Phenoxyacetate

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CAS号96-34-4 氯乙酸甲酯 | CAS号108-95-2 苯酚 | CAS号274251-00-2 4-quinolylmethy... | CAS号74-88-4 碘甲烷 | CAS号96-32-2 溴乙酸甲酯 | CAS号67-56-1 甲醇 | CAS号77-78-1 硫酸二甲酯 | CAS号122-59-8 苯氧乙酸 | CAS号91-16-7 1,2-二甲氧基苯 | CAS号56077-78-2 2-[4-(氯磺酰基)苯氧基]乙酸甲酯 | CAS号4664-55-5 苯氧乙酰肼 | CAS号53961-95-8 N,N'-bis-phenox... | CAS号40665-68-7 (3-苯氧基-2-氧代脯氨酰基... | CAS号21273-38-1 乙二醇苯醚-D2 | CAS号1056469-95-4 2-phenoxy-N-[(R... | CAS号2627-86-3 (S)-(-)-α-甲基苄胺 | CAS号35370-80-0 2-苯氧基硫代乙酰胺 | CAS号7383-14-4 (4-磺酰基-苯氧基)-乙酸 | CAS号122-59-8 苯氧乙酸

苯氧乙酰胺置于sodium Methylate体系中,化学反应 16.0H,反应生成苯氧乙酸甲酯
参考文献:Unexpected Formation Of Acylformamidines By Reaction Of Primary Carboxamides With Meona In Dmf In The Presence Of Chcl3
标题:Unexpected Formation Of Acylformamidines By Reaction Of Primary Carboxamides With Meona In Dmf In The Presence Of Chcl3
摘要:Dichlorocarbene,Which Is Generated By Reaction Of Chcl3 With Meona,Is Likely To Chlorinate Dmf To Produce The Vilsmeier-Haack-Arnold Salt That,In The Presence Of Excess Meona Gives Dmf Dimethylacetal (2). This Latter Reacts With Primary Amides To Yield The Corresponding N,N-Dimethyl-N'-Acylformamidines. Solid State Structure Of N-[(Dimethylamino)Methylene]Phenoxyacetamide (4) Obtained By X-Ray Crystallography Is Also Reported. (C) 1997 Elsevier Science Ltd.
Doi:10.1016/s0040-4020(97)10041-2

专利信息

专利号:US-4922015-A
优先权日:1987-04-08
标 题:Synthesis of peptide amides by means of a solid phase method using acid-labile anchoring groups
发明人：BREIPOHL GERHARD; KNOLLE JOCHEN; STUEBER WERNER
权利人:HOECHST AG
摘要:The invention relates to new compounds of the formula ##STR1## in which R 1 denotes (C 1 -C 8 )-alkyl or optionally substituted (C 6 -C 14 )-aryl, R 2 denotes hydrogen or an amino acid residue which is protected by an amino protective group which can be cleaved off with weak acid or base, R 3 denotes hydrogen or (C 1 -C 4 )-alkyl, and Y 1 -Y 9 denote identical or different radicals hydrogen, (C 1 -C 4 )-alkyl, (C 1 -C 4 )-alkoxy or -O-(CH 2 ) n -COOH (with n=1 to 6), one of these radicals being -O-(CH 2 ) n -COOH. A process for the preparation thereof and the synthesis of peptide amides by means of a solid phase method using these new compounds (spacers) are described.

专利号:US-7022691-B2
优先权日:2002-04-04
标题 :Inhibitors of serine and metallo-β-lactamases
发明人：BUYNAK JOHN D; CHEN HANSONG
权利人:BUYNAK JOHN D; CHEN HANSONG
摘要:Compounds of formula (I): n nwherein R 1 , R 2 , R 3 , R 4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting simultaneously serine and metallo-β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.

专利号:US-7125986-B2
优先权日:1997-12-29
标题:Penicillanic acid derivative compounds and methods of making
发明人：BUYNAK JOHN D; RAO AKIREDDY SRINIVASA; DOPPALAPUDI VENKATA RAMANA
权利人:UNIV SOUTHERN METHODIST
摘要:Compounds of formula I: n nwherein R 1 , R 2 , R 3 , R 4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β-lactamase enzymes, for enhancing the activity of β-lactam antibiotics, and for treating β-lactam resistant bacterial infections in a mammal. The invention also provides pharmaceutical compositions, processes for preparing compounds of formula I, and novel intermediates useful for the synthesis of compounds of formula I.

专利号:WO-0009116-A1
优先权日:1998-08-14
标 题:Grp receptor ligands
发明人：XIANG JIA-NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:EP-0287882-B1
优先权日:1987-04-08
标 题:Synthesis of peptidamides by the solid phase method using anchor groups unstable as to acids

专利号:CN-106278862-A
优先权日:2016-08-04
标题 :A new process for the synthesis of 2,4-dichlorophenoxyacetic acid