CAS: 26177-44-6; (4-Bromophenyl)Methanamine Hydrochloride

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CAS号25062-46-8 4-BROMOBENZALDE... | CAS号107047-10-9 1-(azidomethyl)... | CAS号698-67-9 4-溴苯甲酰胺 | CAS号589-15-1 对溴溴苄 | CAS号589-17-3 4-溴苄氯 | CAS号330794-35-9 4-((N-b°C-氨基)甲基... | CAS号68819-84-1 4-溴苄基氨基甲酸叔丁酯 | CAS号153171-22-3 2-(4-溴苄基)异吲哚啉-1,3-二酮 | CAS号145733-62-6 8-[(4-溴苯基)甲基]-5... | CAS号3959-07-7 4-溴苯甲胺 | CAS号312936-77-9 1-[(4-溴苯基)甲基]-1... | CAS号55301-96-7 (4-benzylsulfan...

4-溴苯腈置于[mn(Hn(C2H4Pipr2)2)(Co)2Br],氢气,Sodium T-Butanolate,盐酸体系中,用 甲苯,乙醚 用作溶剂,120.0 °C,5.0 Mpa 条件下,反应 24.0H,以88%的收率获得4-溴苄胺盐酸盐
参考文献:定义明确的锰钳络合物选择性催化加氢腈,酮和醛
标题:定义明确的锰钳络合物选择性催化加氢腈,酮和醛
摘要:氢化构成有机化学中的基本过程,并允许原子高效和清洁的官能团转化.事实上,用分子氢选择性还原腈,酮和醛可以实现有价值的胺和醇的绿色合成.尽管在均相和多相催化方面取得了一个多世纪的发展,但仍在努力创造新的有用和广泛适用的催化剂体系.最近,地球上丰富的金属在这一领域引起了极大的兴趣.在本研究中,我们首次描述了特定分子定义的锰配合物,这些配合物允许各种极性官能团的氢化.在最佳条件下,我们实现了非常好的官能团耐受性和工业上重要的底物,例如,
Doi:10.1021/jacs.6B03709

专利信息

专利号:US-7968752-B2
优先权日:2003-06-16
标 题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-8895741-B2
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidinones
发明人：WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG
权利人:WU YUSHENG; CHEN SHILI; CHEN YI; HANSELMANN ROGER; LOU RONGLIANG; ZHOU JIACHENG; MELINTA THERAPEUTICS INC
摘要:The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.

专利号:US-12336981-B2
优先权日:2010-09-03
标题 :Compounds and compositions for the inhibition of NAMPT
发明人：BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; DRAGOVICH Peter; GOSSELIN FRANCIS; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; ROTH BRUCE; SMITH CHASE C; WANG ZHONGGUO; YUEN PO-WAI; ZHENG XIAOZHANG
权利人:VALO HEALTH INC; GENENTECH INC
摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

专利号:US-2010022772-A1
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidnones

专利号:US-2013066076-A1
优先权日:2003-06-03
标题:Process for the Synthesis of Biaryl Oxazolidinones

专利号:WO-2005012271-A2
优先权日:2003-07-29
标题 :Process for the synthesis of biaryl oxazolidinones