CAS: 367-30-6; 2,5-Difluoroaniline

上下游产品

CAS号364-74-9 2,5-二氟硝基苯 | CAS号7647-01-0 盐酸 | CAS号39718-32-6 异氰酸2,5-二氟苯酯 | CAS号364-74-9 2,5-二氟硝基苯 | CAS号143925-43-3 N-(2,5-difluoro... | CAS号399-75-7 5-氯-2-甲基苯并噻唑 | CAS号398-90-3 2,5-二氟乙酰苯胺 | CAS号196938-10-0 2-氯-2',5'-二氟乙酰胺 | CAS号288151-26-8 5,8-二氟-4-羟基-2-甲基-喹啉 | CAS号290331-05-4 4-氯-N-[5-氟-2-氟苯... | CAS号77380-28-0 2,5-二氟苯硫酚 | CAS号749240-52-6 4,7-二氟靛红

在 Sodium Tetrahydroborate,Copper(L) Chloride体系中,用 乙醇 用作溶剂,以18.2 Mg的收率获得2,5-二氟苯胺
参考文献:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
标题:阴离子配体促进选择性的c-f键还原消除,使c(sp 2)-h氟化†
摘要:报道了有关阴离子配体促进选择性c-h键氟化的详细机理研究.阴离子配体的作用已通过实验证据和dft计算得以阐明.此外,硝酸盐促进了c-f键的还原性消除,使得各种对称和不对称的偶氮苯能够选择性地进行c-h键氟化,从而获得各种邻氟苯胺.
Doi:10.1039/c9Cc07726J

专利信息

专利号:US-2006167025-A1
优先权日:2004-12-22
标 题:Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs
发明人：BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
权利人:BERGER MARKUS; SCHMEES NORBERT; SCHAECKE HEIKE; BAURLE STEFAN; REHWINKEL HARTMUT; MENGEL ANNE; KROLIKIEWICZ KONRAD; GROSSBACH DANJA; VOIGTLAENDER DAVID
摘要:The invention relates to tricyclic amino alcohols of general formula (I) n nmethod for synthesis of same and use of same as anti-inflammatory agents.

专利号:US-6531470-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-6562844-B2
优先权日:1998-01-23
标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:US-7002020-B1
优先权日:1998-01-23
标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
发明人：GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
权利人:UPJOHN CO
摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

专利号:CA-2586973-A1
优先权日:2004-12-22
标 题 :Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs

专利号:US-9162993-B2
优先权日:2012-04-18
标 题:Preparation and pharmaceuticals of biphenyl benzamide-derived derivatives
发明人：CHANG DEH-MING; HUANG HSU-SHAN; LEE CHIA-CHUNG; CHEN CHUN-LIANG
权利人:NAT DEFENSE MEDICAL CT
摘要:The present invention provides a biphenyl benzamide-derived derivatives, which structure is selected from formula I or formula II n nand the synthesis and the application thereof.