CAS: 651-80-9; 1,2,4,5-Tetrafluoro-3-(Trifluoromethyl)Benzene

上下游产品

CAS号617-86-7 三乙基硅烷 | CAS号434-64-0 八氟甲苯 | CAS号17823-46-0 4-三氟甲基-2,3,5,6-四氟溴苯 | CAS号122571-42-0 4-trimethylsily... | CAS号40885-89-0 4-氯-2,3,5,6-四氟三氟甲基苯 | CAS号1868-85-5 (α,α,α,2,3,5,6-... | CAS号107-05-1 氯丙烯 | CAS号7732-18-5 水 | CAS号54899-60-4 ((4-trifluorome... | CAS号654-87-5 2,3,5-三氟苯甲酸 | CAS号652-18-6 2,3,5,6-四氟苯甲酸 | CAS号17823-46-0 4-三氟甲基-2,3,5,6-四氟溴苯 | CAS号79150-81-5 5-bromo-1,3,3,4... | CAS号40885-89-0 4-氯-2,3,5,6-四氟三氟甲基苯 | CAS号87905-89-3 5-chloro-1,3,3,... | CAS号53700-73-5 1,2,4,5-tetrafl... | CAS号61794-43-2 1,2,4,5-tetrafl... | CAS号61794-47-6 3-[2,3,5,6-tetr...

八氟甲苯置于(Hc[(Cme)N(2,4,6-Me3C6H2)]2)Alh2体系中,用 氘代苯 作为反应溶剂,化学反应 336.0H,反应生成 2,3,5,6-四氟三氟甲苯
参考文献:Piii/pv 合成循环中的往返氧化加成,配体复分解和还原消除
标题:Piii/pv 合成循环中的往返氧化加成,配体复分解和还原消除
摘要:报道了芳基 Cf 取代的合成循环,包括在 Cs 对称磷三酰胺 (1,P{n[o-Nme-C6H4]2}) 上的氧化加成,配体复分解和还原消除.1 与全氟芳烃 (Arf-F) 的反应导致 Cf 氧化加成,反应生成氟正膦 1•[f][arf].通过用 Dibal-H 处理,P-氟取代基被交换为氢化物,反应生成氢化正膦 1•[h][arf].1•[h][arf] 的加热通过 Arf-H 的 Ch 还原消除再生 1,其中实验和计算研究建立了协调但高度异步的机制.结果提供了在单个主要基团位点处的基本机械芳基 Cx 取代步骤的完整三元组的充分表征的例子.
DOI:10.1021/jacs.0C07580

专利信息

专利号:US-2012215002-A1
优先权日:2009-10-09
标 题:Synthesis of optically active intermediate for the preparation of montelukast
发明人：LEFORT LAURENT
权利人:LEFORT LAURENT
摘要:The present invention relates to the synthesis of optically active alcohols by means of enantioselective hydrogenation of ketones in biphasic systems. In particular the present invention relates to the synthesis of an optically active alcohol of general formula (1).

专利号:US-11999757-B2
优先权日:2017-11-01
标 题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:US-2007260076-A1
优先权日:2003-12-05
标 题:Practical, Cost-Effective Synthesis of Ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
权利人:LIPSHUTZ BRUCE H; BERL VOLKER; SHEIN KARIN; WETTERICH FRANK
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-2006167289-A1
优先权日:2003-12-05
标题 :Practical, cost-effective synthesis of ubiquinones
发明人：LIPSHUTZ BRUCE H; BERL VOLKER; SCHEIN KARIN; WETTERICH FRANK
权利人:ZYMES LLC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention. The invention further provides an improved method for the carboalumination of alkyne substrates.

专利号:US-10669292-B2
优先权日:2014-05-05
标 题 :Synthesis of boronate salts and uses thereof
发明人：HECKER SCOTT; BOYER SERGE
权利人:REMPEX PHARMACEUTICALS INC
摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

专利号:US-6852895-B2
优先权日:2000-08-15
标题:Practical, cost-effective synthesis of CoQ10
发明人：LIPSHUTZ BRUCE H; MOLLARD PAUL
权利人:ZYMES INC
摘要:The present invention provides a convergent method for the synthesis of ubiquinones and ubiquinone analogues. Also provided are precursors of ubiquinones and their analogues that are useful in the methods of the invention.