CAS: 700-17-4; 2,3,5,6-Tetrafluoroaniline

上下游产品

CAS号2797-79-7 4-溴四氟苯肼 | CAS号363-72-4 五氟苯 | CAS号771-60-8 2,3,4,5,6-五氟苯胺 | CAS号344-07-0 氯五氟苯 | CAS号392-56-3 六氟苯 | CAS号2248-05-7 (2,3,5,6-tetraf... | CAS号344-04-7 溴五氟苯 | CAS号17823-38-0 4-氨基-2,3,5,6-四氟苯甲腈 | CAS号828-73-9 五氟苯肼 | CAS号103614-94-4 1,2,4,5-tetrafl... | CAS号944-43-4 4-氨基-2,3,5,6-四氟苯甲酸 | CAS号2010-73-3 1,2-bis(2,3,5,6... | CAS号2010-64-2 1,2,4,5-tetrafl... | CAS号2379-20-6 bis(2,3,5,6-tet... | CAS号2379-18-2 oxido-(2,3,5,6-... | CAS号6257-03-0 2,3,5,6-四氟硝基苯 | CAS号332903-60-3 N-(4-Ethylpheny... | CAS号1766-14-9 N-(2,3,5,6-四氟苯基)乙酰胺 | CAS号1998-66-9 4-溴-2,3,5,6-四氟苯胺

五氟苯置于氨体系中,化学反应 10.0H,以89%的收率获得产物2,3,5,6-四氟苯胺
参考文献:多氟苯和吡啶与液氨的选择性单和二胺化
标题:多氟苯和吡啶与液氨的选择性单和二胺化
摘要:五氟吡啶,2,3,5,6-四氟吡啶,4-氯四氟吡啶,3,5-二氯三氟吡啶,八氟甲苯,α,α,α,2,3,5,6-七氟甲苯,十氟间二甲苯,十氟联苯的胺化,六氟苯和五氟苯与液氨进行了研究.大多数底物的双氨基脱氟化温度显着超过单氨基脱氟化的相应温度.阐明了选择性制备单和二氨基多氟(杂)芳烃的最佳条件.提出了一种从五氟苯和六氟苯与氨水基于与冠醚络合的非选择性反应中形成的产物混合物中分离特定多氟苯二胺的有效方法.
DOI:10.1007/s11172-007-0351-2

专利信息

专利号:US-7189749-B2
优先权日:1999-06-25
标 题 :Substituted phenoxyacetic acids
发明人：VAN ZANDT MICHAEL C
权利人:INST FOR PHARM DISCOVERY INC
摘要:Disclosed are substituted phenoxyacetic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds, alone or in combination with other therapeutic agents, and methods of treatment employing the compounds and pharmaceutical compositions, as well as methods for their synthesis.

专利号:US-8163932-B2
优先权日:1998-03-31
标 题 :Substituted indolealkanoic acids
发明人：JONES MICHAEL LEE; GUNN DAVID; JONES JOHN HOWARD; VAN ZANDT MICHAEL C
权利人:JONES MICHAEL LEE; GUNN DAVID; JONES JOHN HOWARD; VAN ZANDT MICHAEL C; ALINEA PHARMACEUTICALS INC
摘要:Disclosed are substituted indolealkanoic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.

专利号:US-7361671-B2
优先权日:2001-11-15
标 题 :Substituted heteroarylalkanoic acids
发明人：VAN ZANDT MICHAEL C; GERACI LEO
权利人:INST PHARMACEUTICAL DISCOVERY
摘要:Disclosed are substituted heteroarylalkanoic acids acids of the following formula D-A-C(O)R′, where D, A, and R′ are defined herein. These compounds are useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds and methods of treatment employing the compounds, as well as methods for their synthesis.