CAS: 80-55-7; Ethyl 2-Hydroxyisobutyrate

该化合物是属于酯类的有机化合物,其特点是无色为黄色液体,有水果味,在调味和香味应用中有用.该化合物的分子式为C6H12O3,表明存在两个功能组:一个酯和一个氢氧基.乙酰2-氢氧素丁酸盐在有机溶剂中溶解,并由于存在氢氧基化合物,在水中表现出中等溶解性.它经常被用作溶剂,并用于各种化合物的合成.此外,由于芳香和香味特征,它在化妆品和食品工业中也有应用.安全数据表明,应当谨慎处理,因为它在接触皮肤或眼睛时可能引起刺激.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

ethanol 2-methyllactic acid ethyl 2-aminoisobutyrate hydr°Chloride 2-hydroxy-2-methylpropanenitrileo-anisidideα-hydroxy-isobutyric acid o-anisidide α-hydroxy-isobutyric acid cyclohexylamide p-toluidideα-hydroxy-isobutyric acid p-toluidide α-hydroxy-isobutyric acid-(4-chloro-anilide)

合成工艺路线路线简述

  • 合成目标产物 Ethyl 2-Hydroxyisobutyrate 主要起始原料 Ethanol And 2-Hydroxyisobutyric Acid
  • 1243055-35-7 = 80-55-7
    反应条件:1.1 Reagents: P-Toluenesulfonic Acid Solvents: Ethanol; 1 H,Rt
    标题:Racemization-Free Monomer: α-Hydroxyisobutyric Acid From Bio-Based Lactic Acid
    作者:Watanabe,Kohtaro; Et Al
    参考文献:Chemistry Letters 日期:2010 卷标:39(7) 页码:698-699]

    1243055-33-5 = 80-55-7
    反应条件:1.1 Reagents: Lithium Diisopropylamide Solvents: Tetrahydrofuran; 30 Min,-84 °C1.2 4 H,-84 °C2.1 Reagents: P-Toluenesulfonic Acid Solvents: Ethanol; 1 H,Rt
    标题:Racemization-Free Monomer: α-Hydroxyisobutyric Acid From Bio-Based Lactic Acid
    作者:Watanabe,Kohtaro; Et Al
    参考文献:Chemistry Letters 日期:2010 卷标:39(7) 页码:698-699]

    58161-11-8 = 80-55-7
    反应条件:1.1 Reagents: Barium Hydroxide Catalysts: Iridium(1+),Carbonyltris(1,3-Dihydro-1,3-Dimethyl-2H-Benzimidazol-2-Ylidene)-,...; 12 H,140 °C; 140 °C -> 70 °C1.2 Reagents: Sulfuric Acid Solvents: Water; Acidified,70 °C2.1 Reagents: Sulfuric Acid Solvents: Ethanol
    标题:Modular Access To Quaternary α-Hydroxyl Acetates By Catalytic Cross-Coupling Of Alcohols
    作者:Zeng,Guangkuo; Et Al
    参考文献:Acs Catalysis 日期:2023 卷标:13(3) 页码:2061-2068]

    = 80-55-7
    反应条件:1.1 Reagents: Hydrochloric Acid
    标题:Ethyl Ester Of α-Hydroxyisobutyric Acid
    作者:Braz,G. I.; Et Al
    参考文献:Zhurnal Obshchei Khimii 日期:1955 卷标:25]

    = 80-55-7
    反应条件:1.1 Reagents: Sulfuric Acid
    标题:Selecting The Process For Your Next Mma Plant
    作者:Porcelli,Richard V.; Et Al
    参考文献:Hydrocarbon Processing 日期:1986 卷标:65(3) 页码:37-43]

    594-61-6 = 80-55-7
    反应条件:1.1 Reagents: Sulfuric Acid Solvents: Ethanol
    标题:Modular Access To Quaternary α-Hydroxyl Acetates By Catalytic Cross-Coupling Of Alcohols
    作者:Zeng,Guangkuo; Et Al
    参考文献:Acs Catalysis 日期:2023 卷标:13(3) 页码:2061-2068]

    594-61-6 = 80-55-7
    反应条件:1.1 Catalysts: Carbon; 300 Psi,150 °C
    标题:Continuous Catalytic Esterification Using A Solid Acid Activated Carbon Monolith: Comparison Of Granular And Monolith Forms With A Commercial Catalyst
    作者:Sripada,Sarada; Et Al
    参考文献:Chemical Engineering Journal (Amsterdam 日期:2023 卷标:476]

    = 80-55-7
    反应条件:1.1 Reagents: Oxygen Catalysts: (Sp-5-13)-Chloro[[2,2′-[(2,2-Dimethyl-1,3-Propanediyl)Bis[(Nitrilo-Kn)Methylidyn... Solvents: Chloroform; 1 Atm,0 °C1.2 Reagents: Sodium Borohydride Solvents: Ethanol; 20 Min,0 °C; 4 H,Rt
    标题:(Schiff-Base)Mn(Iii)-Catalyzed Hydroxylation Of α,β-Unsaturated Esters Using Molecular Oxygen In The Presence Of Metal Hydrides
    作者:Baik,Jong Seok; Et Al
    参考文献:Bulletin Of The Korean Chemical Society 日期:2006 卷标:27(2) 页码:333-334]

    594-61-6 + 925-93-9 = 80-55-7
    反应条件:1.1 Catalysts: Sulfuric Acid Solvents: Ethanol-D; 24 H,Reflux
    标题:The Discovery Of A Potent And Selective Pyrazolo-[2,3-E]-[1,2,4]-Triazine Cannabinoid Type 2 Receptor Agonist
    作者:Moir,Michael; Et Al
    参考文献:European Journal Of Medicinal Chemistry 日期:2021 卷标:210]

    823-16-5 = 80-55-7
    反应条件:1.1 Reagents: Sodium Nitrite,Nitric Acid
    标题:Oxidation Of 1,3- And 1,4-Dioxanes By Nitric Acid
    作者:Gevorkyan,A. A.; Et Al
    参考文献:Armyanskii Khimicheskii Zhurnal 日期:1991 卷标:44(7-8) 页码:443-8]

    57-55-6 = 80-55-7
    反应条件:1.1 Reagents: Barium Hydroxide Catalysts: Iridium(1+),Carbonyltris(1,3-Dihydro-1,3-Dimethyl-2H-Benzimidazol-2-Ylidene)-,...; 4 H,140 °C; 140 °C -> 70 °C1.2 Reagents: Sulfuric Acid Solvents: Water; Acidified,70 °C2.1 Reagents: Sulfuric Acid Solvents: Ethanol
    标题:Modular Access To Quaternary α-Hydroxyl Acetates By Catalytic Cross-Coupling Of Alcohols
    作者:Zeng,Guangkuo; Et Al
    参考文献:Acs Catalysis 日期:2023 卷标:13(3) 页码:2061-2068]

    = 80-55-7
    反应条件:1.1 -2.1 Reagents: Sulfuric Acid
    标题:Selecting The Process For Your Next Mma Plant
    作者:Porcelli,Richard V.; Et Al
    参考文献:Hydrocarbon Processing 日期:1986 卷标:65(3) 页码:37-43
2-氨基异丁酸乙酯盐酸盐置于盐酸,Sodium Nitrite体系中,化学反应生成 2-羟基异丁酸乙酯
参考文献:Barker; Skinner,Journal Of The American Chemical Society,1924,Vol. 46,P. 412
标题:Barker; Skinner,Journal Of The American Chemical Society,1924,Vol. 46,P. 412

海关参考信息

专利信息


专利号:US-8475998-B2
优先权日:2010-12-20
标 题 :Compound synthesis method, microarray, acid-transfer composition, and biochip composition
发明人:YUN HYOJIN; YOO CHANGEUN; KIM MYUNG-SUN; KIM SOO-KYUNG; NISHIKAWA KOUJI; GOTO HIROFUMI; MIYAMOTO HIDETOSHI
权利人:YUN HYOJIN; YOO CHANGEUN; KIM MYUNG-SUN; KIM SOO-KYUNG; NISHIKAWA KOUJI; GOTO HIROFUMI; MIYAMOTO HIDETOSHI; SAMSUNG ELECTRONICS CO LTD; JSR CORP
摘要:A compound synthesis method includes bonding a first compound to a substrate to form a first film. A second film is formed on the first film using an acid-transfer composition including (A) a polymer that includes a structural unit shown by a following formula (1) and a structural unit shown by a following formula (2), (B) a photoacid generator shown by a following formula (3), and (C) a sensitizer shown by a following formula (4). The second film is exposed to remove the protecting group from the first compound under an exposed area of the second film. An acid generated in the exposed area of the second film is transferred to the first film. The second film after being exposed is removed. A second compound is bonded to the first compound from which the protecting group has been removed.

专利号:US-12122751-B2
优先权日:2019-06-25
标 题 :Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives
发明人:JIAO XIANGDONG; KHUMTAVEEPORN KANJAI
权利人:TRANSLATUM MEDICUS INC
摘要:The invention in this disclosure is related to the processes of making Bindarit or derivatives thereof. Specifically, the present invention provides, in part, new processes for making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives. By way of non-limiting example, synthesis and purification processes of 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid are provided by the invention in this disclosure.

专利号:US-8043786-B2
优先权日:2003-03-05
标题 :Acid generators, sulfonic acids, sulfonyl halides, and radiation sensitive resin compositions
发明人:EBATA SATOSHI; WANG YONG; NISHIMURA ISAO
权利人:JSR CORP
摘要:The invention provides novel acid generators which are unproblematic in combustibility and accumulation inside the human body and can generate acids having high acidities and high boiling points and exhibiting properly short diffusion lengths in resist coating films and which permit the formation of resist patterns excellent smoothness with little dependence on the denseness of a mask pattern; sulfonic acids generated from the acid generators; sulfonyl halides useful as raw material in the synthesis of the acid generators; and radiation-sensitive resin compositions containing the acid generators. The acid generators have structures represented by the general formula (I), n nwherein R 1 is a monovalent substituent such as alkoxycarbonyl, alkylsulfonyl, or alkoxysulfonyl; R 2 to R 4 are each hydrogen or alkyl; k is an integer of 0 or above; and n is an integer of 0 to 5. Among the radiation-sensitive resin compositions, a positive one contains a resin having acid-dissociable groups in addition to the above acid generator, while a negative one contains an alkali-soluble resin and a crosslinking agent in addition to the acid generator.

专利号:US-7754188-B2
优先权日:2003-06-30
标 题:Radiolabeled cannabinoid-1 receptor modulators
发明人:BURNS H DONALD; CHEN ALEX M; GIBSON RAYMOND E; GOULET MARK T; HAGMANN WILLIAM K; HAMILL TERENCE G; JEWELL JAMES P; LIN LINUS S; LIU PING; PERESYPKIN ANDREY V
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to particular radiolabeled Cannabinoid-1 (CB1) receptor modulators, and methods of using these modulators for labeling and diagnostic imaging of Cannabinoid-1 receptors in mammals, particularly humans. In addition, intermediates useful for the synthesis of the radiolabeled Cannabinoid-1 receptor modulators are also disclosed, as well as the processes for synthesizing the radiolabeled Cannabinoid-1 receptor modulators. Still further, formulations of the radiolabeled Cannabinoid-1 receptor compounds are described.

专利号:CN-110997605-A
优先权日:2017-08-02
标题:Synthesis of diols by transfer hydrogenation of α-functionalized esters with alcohols

专利号:WO-2019027948-A1
优先权日:2017-08-02
标 题 :SYNTHESIS OF GLYCOLS USING HYDROGENATION BY TRANSFERRING ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS
博医化工有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.pharmabl.com
电话: 86-512-58189390👤
📞博医化工有限公司 ⚠️参考联系方式

销售电话:86-512-58189390
邮箱:info@pharmabl.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
天津杰众国际贸易有限公司
⚠️ 未注册 · 未认证企业
⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
数据来源于公开网络搜索,平台未作核实,请自行辨别。
🏢敬请 企业认领
🏬开设公司展台
📢获取免费会员权益
🎖️点亮专属注册企业标签
📇展现公司完整信息 样本查看立即注册认领 →
网址: http://www.visonmed.com
电话: 0086 022 23511660 23358985👤
📞天津杰众国际贸易有限公司 ⚠️参考联系方式

销售电话:0086 022 23511660 23358985
邮箱:info@visonmed.com.
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

⚠️ 未注册 · 未认证企业
注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
第 1 / 1 页
现货

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Vandamme, M.; Paquin, J.-F., Science of Synthesis Knowledge Updates, (2016) 1, 399.
📝 需求与反馈
尽可能描述清楚需求与问题信息
×

通知