CAS: 19398-61-9; 1,4-Dichloro-2-Methylbenzene

上下游产品

CAS号95-49-8 邻氯甲苯 | CAS号108-41-8 间氯甲苯 | CAS号6639-30-1 2,4,5-三氯甲苯 | CAS号108-88-3 甲苯 | CAS号95-70-5 2,5-二氨基甲苯 | CAS号10026-13-8 五氯化磷 | CAS号56157-92-7 4-氯-2-甲基苯磺酰氯 | CAS号95-69-2 4-氯-2-甲基苯胺 | CAS号50-82-8 2,4,5-三氯苯甲酸 | CAS号50-79-3 2,5-二氯苯甲酸 | CAS号50-31-7 2,3,6-三氯苯甲酸 | CAS号6639-30-1 2,4,5-三氯甲苯 | CAS号2077-46-5 2,3,6-三氯甲苯 | CAS号85482-13-9 2,5-二氯溴苄 | CAS号2745-49-5 2,5-二氯氯苄 | CAS号66192-24-3 1-溴-2-溴甲基-4-氯苯 | CAS号6361-23-5 2,5-二氯苯甲醛 | CAS号59-50-7 4-氯-3-甲基苯酚

2-氯甲苯置于a K-L-Type Zeolite 氯体系中,用 1,2-二氯乙烷 用作溶剂,化学反应 2.0H,反应生成2,5-二氯甲苯
参考文献:Ep1508557
标题:Ep1508557

专利信息

专利号:US-7968673-B2
优先权日:2007-02-20
标 题:Polyazacrown-based materials for mercury capture and synthesis of those materials
发明人：REDKO MIKHAIL Y; JACKSON JAMES E; TARABARA VOLODYMYR; TAUROZZI JULIAN
权利人:UNIV MICHIGAN STATE
摘要:Polyazacrown polymers based on the azacrown monomer 1,4,7,10,13,16,21,24-octaazabicyclo[8.8.8]hexacosane (“H 6 Aza222â€?) are disclosed. Azacrown monomer units are preferably linked with a suitable linking agent, and the resulting polymers are can absorb mercury from a water stream and form a stable complex therewith. Methods of making and using the polyazacrown polymers are also disclosed. The polymers have a high absorption capacity for and selectivity towards mercury, which properties are useful for the remediation of mercury-contaminated water. The polymers can be regenerated by the efficient removal of the absorbed mercury. Further, the absorbed mercury that is liberated from the polyazacrown polymers can be effectively concentrated and captured to prevent its re-release into the environment.

专利号:US-6828466-B2
优先权日:2002-07-19
标题:Process for the synthesis of phenols from arenes
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL; SHI FENG
权利人:UNIV MICHIGAN STATE
摘要:A process to synthesize substituted phenols such as those of the general formula RR'R''Ar(OH) wherein R, R', and R'' are each independently hydrogen or any group which does not interfere in the process for synthesizing the substituted phenol including, but not limited to, halo, alkyl, alkoxy, carboxylic ester, amine, amide; and Ar is any variety of aryl or hetroaryl by means of oxidation of substituted arylboronic esters is described. In particular, a metal-catalyzed C-H activation/borylation reaction is described, which when followed by direct oxidation in a single or separate reaction vessel affords phenols without the need for any intermediate manipulations. More particularly, a process wherein Ir-catalyzed borylation of arenes using pinacolborane (HBPin) followed by oxidation of the intermediate arylboronic ester by OXONE is described.

专利号:US-7153933-B2
优先权日:2001-12-07
标 题 :Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same
发明人：WU SHIH-KWANG; CHANG TING-GUNG; TSENG CHIN-LU; CHEN LI-JUNG; SHIH KAE-SHYANG
权利人:DEV CENTER BIOTECHNOLOGY
摘要:A solid phase synthesis method for preparing peptide-spacer-lipid conjugates, the peptide-spacer-lipid conjugates synthesized by the method, and liposomes containing the peptide-spacer-lipid conjugates. The present invention provides a convenient solid phase synthesis method for preparing peptide-spacer-lipid conjugates and provides various linkage groups (such as amide group) for conjugating peptide, spacer and lipid, wherein the spacer may comprise PEG. Several advantages can be achieved, such as the synthetic procedure can be simplified, the synthesis process can be set to automation, the purification is easier in each reaction step, and the product losses can be reduced to minimal during synthesis. The present synthesis method is suitable for preparing a wide range of peptide-spacer-lipid conjugates, provides a peptide-spacer-lipid conjugate prepared by the solid phase synthesis method of the present invention, which can be incorporated into a liposome as the targeting moiety for liposomal drug delivery to specific cells, and provides a targeting liposome containing the present peptide-spacer-lipid conjugate.

专利号:US-2006052532-A1
优先权日:2002-04-10
标 题 :Swellable, easily cross-linked, essentially linear polymers, and the use of the same in solid phase synthesis
发明人：RADEMANN JORG
权利人:RADEMANN JORG
摘要:The invention relates to a novel polymer compound, the use of the same and a method for solid phase synthesis using an inventive polymer compound. Said polymer compound comprises linear polymer chains of general formula [R—X]n, wherein R represents a hydrocarbon group and X represents a group comprising at least one heteroatom. The linear polymer chains are cross-linked with each other by means of linking groups.

专利号:US-2009057233-A1
优先权日:2007-02-20
标题:Polyazacrown-based materials for mercury capture and synthesis of those materials

专利号:US-9771356-B2
优先权日:2012-09-21
标题 :Inhibitors of beta-hydroxylase for treatment of cancer
发明人：WANDS JACK R; DE LA MONTE SUZANNE; AIHARA ARIHIRO; OLSEN MARK JON; THOMAS JOHN-MICHAEL
权利人:RHODE ISLAND HOSPITAL; UNIV MIDWESTERN
摘要:The present invention relates to compounds which modulate (e.g., inhibit) the activity of beta-hydroxylase (e.g., Asparatyl (asparaginyl) β-hydroxylase (ASPH)), including novel 2-aryl-5-amino-3(2H)-furanone and 2-heteroaryl-5-amino-3(2H)-furanone compounds, pharmaceutical compositions thereof, methods for their synthesis, and methods of using these compounds to modulate the activity of ASPH in an a cell-free sample, a cell-based assay, and in a subject. Other aspects of the invention relate to use of the compounds disclosed herein to ameliorate or treat cell proliferation disorders.