CAS: 1693-28-3; 2-(Trifluoromethyl)Thioxanthen-9-One

相似化合物

5495-84-1 492-22-8 15774-82-0

2-氟苯硫酚置于sodium Hydroxide,Sodium Hydride,Magnesium体系中,用 六甲基磷酰三胺,N,N-二甲基甲酰胺 用作溶剂,化学反应 26.0H,反应生成2-三氟甲基噻吨酮
参考文献:Tricyclic Psychotropic Agents Containing Two Chalcogen Atoms In The Central Ring: 8-Substituted 6-(4-Piperidyl)-6H-Dibenz[b,E]-1,4-Oxathiepins
标题:Tricyclic Psychotropic Agents Containing Two Chalcogen Atoms In The Central Ring: 8-Substituted 6-(4-Piperidyl)-6H-Dibenz[b,E]-1,4-Oxathiepins
摘要:2-(2-氟苯硫基)苯甲醛ixa-C和5-氯-2-(2-氟苯硫基)乙酰苯酮分别与1-甲基-4-哌啶基镁氯化物和3-二甲氨基丙基镁氯化物反应,生成的氨基醇via-C,Xvii和xviii在二甲基甲酰胺中与氢化钠发生环化反应.除了标题化合物ia-C,Xix和xx之外,还得到了几种类型的副产物.通过氯甲酸酯法对化合物ib进行去甲基化得到二级胺iib,进而转化为氨基醇iiib和vb.化合物ia-C是非常有效的神经阻滞剂,具有很高的中枢抑制和猫病活性.氨基醇vb在大鼠中表现出很强的抗阿波吗啡效果.
Doi:10.1135/cccc19823077

专利信息

专利号:US-7598019-B2
优先权日:2002-03-04
标 题:Method for cleavage of labile functional groups from chemical compounds
发明人：STEINER ULRICH; WOLL DOMINIK; WALBERT STEFAN
权利人:UNI KONSTANZ
摘要:The present invention provides a method for cleavage of labile functional groups from molecules by the action of electromagnetic radiation, wherein the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group, and are subsequently exposed to electromagnetic radiation. Further, the invention provides a method for preparing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates, said method comprising the following steps: a) reacting the unprotected terminal 3′ or 5′ hydroxy group of a nucleoside and/or of a nucleotide arranged on the solid substrate under usual conditions with a photolabile protective group and optionally purifying the reaction product, b) applying a solution, suspension or dispersion of a chemical compound, whose triplet state is energetically higher than the triplet state of the photolabile protective group, to the surface of the carrier, said surface comprising the nucleotides and/or nucleosides modified in step a): c) irradiating, in a spatially selective manner, the surface of the carrier treated in step b) with electromagnetic radiation in the UV/VIS range with simultaneous, spatially selective release of a reactive OH group and subsequently reacting it with a nucleoside and/or nucleotide comprising a 5′ or 3′OH group, said nucleoside and/or nucleotide being further provided with a photolabile functional group. Moreover, the present invention provides a chemical composition comprising a molecule having a labile functional group, as well as a chemical compound whose triplet state is higher than the triplet state of the labile functional group, and it describes the use of the chemical composition for preparing DNA chips.

专利号:CN-111138411-B
优先权日:2019-12-17
标 题 :A kind of ultraviolet light-promoted synthesis method of thioxanthones compounds

专利号:CN-111138411-A
优先权日:2019-12-17
标题:A kind of ultraviolet light-promoted synthesis method of thioxanthones compounds

专利号:CN-106905284-B
优先权日:2017-02-24
标题 :A kind of catalytic oxidation synthesis method of xanthone compounds

专利号:CN-109232525-B
优先权日:2018-09-27
标题:A photocatalytic oxidation synthesis method of thioxanthone compounds

专利号:CN-109232525-A
优先权日:2018-09-27
标 题:A kind of photocatalytic oxidation synthesis method of thioxanthone compounds