专利号:US-2012190064-A1 优先权日:2004-10-01 标题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules 发明人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA 权利人:KUDLICKI WIESLAW ANTONI; KEPPETIPOLA SHIRANTHI; FLETCHER JULIA; GETBEHEAD ASHLEY ELAINE; KATZEN FEDERICO; VOZZA-BROWN LAURA; LIFE TECHNOLOGIES CORP 摘要:Compositions, methods and kits for in vitro systems for synthesis of biomolecules such as polypeptides, are provided herein. Cell extracts that provide enhanced yields of soluble proteins using in vitro protein synthesis methods are provided. The invention also includes methods for producing high yields of proteins by the addition of a feeding solution that includes amino acids and an energy source to an ongoing in vitro synthesis system. The invention also includes methods of using a high-yield in vitro synthesis system to produce large quantities of proteins with incorporated labeled amino acids for analysis by methods such as by NMR. The invention further includes vectors for enhanced production of proteins from nucleic acid templates using in vitro synthesis systems.
专利号:US-2024309142-A1 优先权日:2023-03-17 标题 :Capped block copolymers, their synthesis, manufacture, and methods of use 发明人:MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON 权利人:ECOLAB USA INC 摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.
专利号:US-2013243770-A1 优先权日:2005-10-14 标 题:Treating diabetes using inhibitors of il-1 发明人:LAU JESPER 权利人:NOVO NORDISK AS 摘要:The present invention describes a method of treating diabetes or metabolic syndrome with a compound that inhibits (a) IL-1, (b) the synthesis of IL-1, or (c) the release of IL-1.
专利号:US-3635829-A 优先权日:1969-05-19 标题 :Detergent formulations 发明人:YANG MEILING T 权利人:ETHYL CORP 摘要:To obviate eutrophication of water, nonphosphorus detergent builders are provided. These are the water-soluble salts of 2-(N, N-di-(carboxymethyl))amino-3-sulfopropionic acid (e.g., the tetrasodium salt thereof). Conventional detergent actives may be used with these builders. Synthesis of the builders is described.
专利号:US-3637511-A 优先权日:1969-05-19 标题:Detergent formulations 发明人:YANG MEILING T 权利人:ETHYL CORP 摘要:To obviate eutrophication of water, nonphosphorus detergent builders are provided. These are the water-soluble salts of N,N,di(carboxymethyl)-aspartic acid (e.g., the tetrasodium salt thereof). Conventional detergent actives may be used with these builders. Synthesis of the builders is described.
专利号:US-2009209032-A1 优先权日:2004-10-01 标 题 :Feeding buffers, systems, and methods for in vitro synthesis of biomolecules
[参考文献]: C Causeret, Et Al. Further Characterization Of Rat Dihydroceramide Desaturase: Tissue Distribution, Subcellular Localization, And Substrate Specificity. Lipids. 2000 Oct;35(10):1117-25. [参考文献]: Francisco J Prado-Prado, Et Al. Multi-Target Spectral Moment Qsar Versus Ann For Antiparasitic Drugs Against Different Parasite Species. Bioorg Med Chem. 2010 Mar 15;18(6):2225-2231. [参考文献]: H Erdjument-Bromage, Et Al. Examination Of Micro-Tip Reversed-Phase Liquid Chromatographic Extraction Of Peptide Pools For Mass Spectrometric Analysis. J Chromatogr A. 1998 Nov 27;826(2):167-81. [参考文献]: R J Barry, Et Al. Solubilization And Partial Purification Of Retinyl Ester Synthetase And Retinoid Isomerase From Bovine Ocular Pigment Epithelium. J Biol Chem. 1989 Jun 5;264(16):9231-8. [参考文献]: R Parvin, Et Al. Inhibition Of Mitochondrial Carnitine-Acylcarnitine Translocase By Sulfobetaines. Can J Biochem. 1980 Oct;58(10):822-30.
合成参考文献
参考文献:10.1007/s11743-016-1838-3 摘要:Wieczorek D, Gwiazdowska D, Staszak K, Chen Y, Shen T. Surface and Antimicrobial Activity of Sulfobetaines. J Surfact & Detergents. 2016 May 31;19(4):813–22. doi: 10.1007/s11743-016-1838-3. 参考文献:10.1007/978-981-99-2544-5_10 摘要:Ekanayake A, Rajapaksha AU, Vithanage M. Organoclay with Surfactants: Detoxification of Hazardous Compounds. 2023. In: Advances in Material Research and Technology. 参考文献:10.1007/978-3-032-07376-1_1 摘要:Rafaqat A, Zubair M, Rahdar A, Nadeem R, Ashfaq M, Mustafa G, Zafar MN. Micelle Formation by Surfactants. 2026. In: Advances in Material Research and Technology. 参考文献:10.1007/bf00762529 摘要:Bowman BJ, Vázquez-Laslop N, Bowman EJ. The vacuolar ATPase ofNeurospora crassa. Journal of Bioenergetics and Biomembranes. 1992 Aug;24(4):361–70. doi: 10.1007/bf00762529.