CAS: 3958-57-4; 1-(Bromomethyl)-3-Nitrobenzene

上下游产品

CAS号619-25-0 3-硝基苯甲醇 | CAS号99-61-6 间硝基苯甲醛 | CAS号99-08-1 3-硝基甲苯 | CAS号142509-31-7 1-((methoxymeth... | CAS号7726-95-6 溴素 | CAS号56-23-5 四氯化碳 | CAS号128-08-5 N-溴代丁二酰亚胺 | CAS号78-67-1 偶氮二异丁腈 | CAS号859146-54-6 (3'-nitrobenzyl... | CAS号141451-73-2 methyl 1-[(3-ni... | CAS号15184-95-9 (3-硝基苯基)-N,N-二甲基甲胺 | CAS号4623-24-9 2-(3-氨基苯基)乙腈 | CAS号198281-55-9 3-[(4-甲基-1-哌嗪基)甲基]苯胺 | CAS号198281-54-8 1-甲基-4-(3-硝基苄基)哌嗪 | CAS号21388-97-6 3-硝基乙酸苄酯 | CAS号99-61-6 间硝基苯甲醛 | CAS号28485-00-9 2,4(1H,3H)-Pyri... | CAS号261924-46-3 1-(methylsulfon... | CAS号2767-70-6 (4-硝基苄基)三苯基溴化磷

间硝基苯甲酸置于sodium Tetrahydroborate,三溴化磷体系中,用 甲醇,二氯甲烷 作为反应溶剂,化学反应 2.5H,反应生成 3-硝基溴苄
参考文献:新型三唑结合的伊斯汀衍生物作为抗真菌剂,抗结核剂和抗氧化剂的合成及分子对接研究
标题:新型三唑结合的伊斯汀衍生物作为抗真菌剂,抗结核剂和抗氧化剂的合成及分子对接研究
摘要:通过点击化学有效制备的1,2,3-三唑库,并对其抗真菌,抗结核,抗氧化剂,细胞毒性,分子对接和adme预测进行了评估.
DOI:10.1002/jhet.2598

专利信息

专利号:WO-2024174285-A1
优先权日:2023-02-21
标题:Method for preparing halogenated compound from metal halide salt on basis of mobile phase
发明人：SU REN; Ye Jiani
权利人:UNIV SOOCHOW
摘要:Disclosed is a method for preparing a halogenated compound from a metal halide salt on the basis of a mobile phase. The method comprises: converting an aromatic hydrocarbon, alkane or nitrile compound into a halogenated compound by means of a cheap metal halide salt and a photocatalyst under illumination. The method uses a cheap and safe halide salt as a halogen source, does not introduce additional elemental halogen or an additional oxidant, can implement a reaction at normal temperature and normal pressure, is high in terms of selectivity and friendly to environment, and can be used for replacing an existing synthesis reaction system for halogenated compounds. A mobile phase device is used to replace a tank reactor, such that operation is easy and convenient, the price is low, the substrate adaptability is high, the continuous synthesis of halogenated compounds can be achieved, and the method is suitable for industrial large-scale production.

专利号:WO-9943409-A1
优先权日:1998-02-27
标 题:Hplc fractionation of complex chemical mixtures
发明人：COOK PHILLIP DAN; CUMMINS LENDELL L; GRIFFEY RICHARD H; KAWASAKI ANDREW M; GAUS HANS; AN HAOYUN
权利人:ISIS PHARMACEUTICALS INC; COOK PHILLIP DAN; CUMMINS LENDELL L; GRIFFEY RICHARD H; KAWASAKI ANDREW M; GAUS HANS; AN HAOYUN
摘要:The rapid deconvolution of complex chemical mixtures, such as combinatorial libraries prepared via solution-phase simultaneous addition of functionalities is demonstrated using HPLC. Libraries containing 25-216 members were screened for biological activity and active libraries are fractionated into discreet pools using preferred reversed-phase HPLC. The entire process can be completed from a single synthesis of 15-50 mg, without the need for fixed positions, serial synthesis, or tagging.

专利号:US-6150129-A
优先权日:1996-08-01
标 题 :Antimicrobial determination of N-(aminoalkyl) and/or N-(Amidoalkyl) dinitrogen heterocyclic compositions
发明人：COOK PHILLIP DAN; KAWASAKI ANDREW M; KUNG PEI PEI
权利人:ISIS PHARMACEUTICALS INC
摘要:Compositions are provided comprising novel di-nitrogen heterocycle compounds containing N-(aminoalkyl) and/or N-(amidoalkyl) groups. An additional situs of functionality is also provided. The compounds and compositions of the invention are useful as antibacterial and other pharmaceutical agents and as intermediates for preparation of other pharmaceutical agents. In addition, compounds of the present invention are useful as research reagents including employment as species for effecting combinatorial synthesis.

专利号:US-7179918-B2
优先权日:2001-06-11
标 题:HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis
发明人：CANAN KOCH STACIE S; ALEXANDER THERESE N; BURKE BENJAMIN J; JEWELL TANYA M; KUCERA DAVID J; LINTON MARIA ANGELICA; MITCHELL JR LENNERT J; REICH SIEGFRIED H; SKALITZKY DONALD J; TATLOCK JOHN H; VARNEY MICHAEL D; VIRGIL SCOTT C; WEBBER STEPHEN E; WORLAND STEPHEN T; BARVIAN MARK; BOLTON GARY; BOYER JR FREDERICK EARL; MACHAK JEFFREY J; HOLLER TOD; MURPHY SEAN T; MELNICK MICHAEL; JOSYULA VARA PRASAD
权利人:AGOURON PHARMA
摘要:Compounds of the formula: n nwhere the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.

专利号:WO-0220630-A1
优先权日:2000-09-08
标 题 :Process for the preparation of glycerol-based crosslinked polymeric gels
发明人：PILLAI V N RAJASEKHARAN; DHANAPAL BOOPATHY
权利人:LIPAL BIOCHEMICALS; PILLAI V N RAJASEKHARAN; DHANAPAL BOOPATHY
摘要:The present invention relates to a process for the preparation of crosslinked polymeric gels for solid phase synthesis, the respective gels and their use. The gels are prepared by radical-induced copolymerisation of monomeric molecules and bifunctional crosslinking agents.

专利号:US-9156840-B2
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use
发明人：LUEHR GARY W; SUNDARAM ARATHI; JAISHANKAR PRIYADARSHINI; PAYNE PHILIP W; DRUZGALA PASCAL
权利人:ALTOS THERAPEUTICS LLC
摘要:Provided are D 2 or D 3 antagonist compounds and pharmaceutical compositions of formula I n nand pharmaceutically acceptable salts thereof, or isomers thereof, wherein R 1 , R 2 and R 3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D 2 or D 3 receptor from the compounds of the invention.