CAS: 888711-47-5; Potassium Trifluoro(Iodomethyl)Borate

相似化合物

13862-28-7 888854-43-1

二碘甲烷置于正丁基锂,硼酸三异丙酯,Potassium Hydrogen Bifluoride体系中,用 四氢呋喃,正己烷,水 作为反应溶剂,化学反应 1.0H,以89%的收率获得产物(碘甲基)三氟硼酸钾
参考文献:Synthesis Of Functionalized Organotrifluoroborates Via Halomethyltrifluoroborates
标题:Synthesis Of Functionalized Organotrifluoroborates Via Halomethyltrifluoroborates
摘要:Potassium Bromo-And Iodomethyltrifluoroborates Have Been Prepared Via In Situ Reaction Of N-Buli With Dibromo-And Diiodomethane,Respectively,In The Presence Of Trialkyl Borates,Followed By Treatment With Khf2. Moreover,A New Synthetic Method For The Preparation Of Potassium Organotrifluoroborates Through Nucleophilic Substitution Of The Halide In These Potassium Halomethyltrifluoroborates Is Described.
DOI:10.1021/ol060375A

专利信息

专利号:US-9518067-B2
优先权日:2013-03-27
标题 :Trifluoroborate mass spectrometric tags
发明人：HUANG YUMEI
权利人:CELLMOSAIC INC
摘要:The invention provides compositions and methods for mass spectrometric (MS), organic synthesis, and applications of organo-trifluoroborate, for example, as mass tags for use in negative ion mode. When subject to MS fragmentation, organo-trifluoroborates preferentially undergo neutral losses of hydrogen fluoride (HF) or boron trifluoride (BF 3 ) molecules, transferring the negative charge to the rest of the molecule. Such a fragmentation pattern is used to detect and quantitate analytes of interest after derivatization with organo-trifluoroborates.