专利号:US-11529370-B2 优先权日:2017-11-24 标 题 :Use of composition comprising stem cell-derived exosome as effective ingredient in strengthening skin barrier and improving skin barrier function 发明人:YI YONG WEON; CHO BYONG SEUNG 权利人:EXOCOBIO INC 摘要:A composition for strengthening skin barrier or improving skin barrier function is able to improve objective indicators related to the protection of skin barrier, the strengthening of skin barrier, and/or the improvement of skin barrier function. The composition exhibits the effects of increasing the amount of ceramides, dihydroceramides and sphingoid bases, increasing the activities of enzymes that are involved in the synthesis thereof, and decreasing the activities of enzymes that are involved in the degradation thereof. In addition, the composition is able to restore skin barrier function by reducing TSLP, IL-4, and IL-13 which are closely associated with skin barrier damage, and thus interrupting a vicious circle in which the lipids and proteins contributing to skin barrier decrease.
专利号:US-2012213845-A1 优先权日:2010-10-19 标题 :Skin composition comprising an exfoliate, a brightener and a collagen booster, and method of using the same 发明人:BERNSTEIN ERIC F 权利人:BERNSTEIN ERIC F 摘要:There is disclosed a composition that provides improved anti-aging benefits and creates a healthier skin using the combination of skin exfoliation, brightening, and collagen synthesis. In one embodiment, the composition comprises, a skin exfoliation ingredient such as citric acid and gluconolactone, at least one skin brightening ingredient, such licorice extract, and at least one collagen enhancing ingredient, such as hydroxyproline, bioactive polypeptides or combinations thereof. Depending on the end-use, various optional ingredients, such as moisturizers, anti-inflammatory agents, UVA/UVB protectants, and cleansers, may be added to the composition, which may take various forms, such as a cream, mousse, serum, or gel.
专利号:WO-2006053688-A1 优先权日:2004-11-17 标 题:Cosmetic and dermatological preparations for the treatment of mature skin 发明人:DOERING THOMAS 权利人:HENKEL KGAA; DOERING THOMAS 摘要:The invention relates to topical cosmetic or dermatological compositions for the treatment of mature or intrinsically or extrinsically aged skin, in particular, for anti-wrinkle treatment, containing a combination of at least two selected peptides in a suitable cosmetic or dermatological vehicle, which have an effect at differing points of the process of collagen and/or fibronectin synthesis.
专利号:CZ-310361-B6 优先权日:2023-04-28 标 题:Ester conjugate of sphingolipid and hyaluronan, method of synthesis thereof, composition containing same, use of said conjugate or composition
专利号:DE-102011089270-A1 优先权日:2011-12-20 标 题:Use of a combination of taurine and hydrolysed protein from yeast to increase epidermal lipid synthesis
专利号:US-7887858-B2 优先权日:2007-01-30 标 题:Cosmetic composition containing an amber extract 发明人:CAUCHARD JEAN-HUBERT; BONTE FREDERIC; ARCHAMBAULT JEAN-CHRISTOPHE 权利人:LVMH RECH 摘要:A cosmetic composition includes as active agents, a first active agent consisting of an amber extract, and at least one other cosmetically active agent selected from the group consisting of extracts of Bertholletia excelsa , extracts of Potentilla erecta , magnesium aspartate, peptides acting on muscle contraction, particularly acetyl hexapeptide 3, peptides and their derivatives grafted with a fatty acid, particularly a C 16 fatty acid, promoting collagen synthesis, particularly palmitoyl oligopeptide pentapeptide 3 or palmitoyl tetrapeptide 7, soy flour hydrolyzates and plant glycolipids, particularly cereal glycosphingolipids and more particularly wheat glycosphingolipids. An amber extract also may be used as a cosmetic agent acting on the dermal supporting proteins and/or the enzymatic systems that degrade the dermal proteins and/or the glycan-type essential components of the extracellular matrix, particularly proteoglycans, for improving the essential biomechanical properties of the skin, namely firmness and elasticity, in the preparation of a cosmetic composition.
参考标题:Sustainable Peptide Synthesis Enabled By A Transient Protecting Group 作者:Sascha Knauer,Niklas Koch,Christina Uth,Reinhard Meusinger,Olga Avrutina,Harald Kolmar |发布日期:2020.7.27 摘要:(Smoc) Protecting Group. This Approach Enables Peptide Assembly Under Aqueous Conditions, Real‐time Monitoring Of Building Block Coupling, And Efficient Postsynthetic Purification. The Procedure For The Synthesis Of All Natural And Several Non‐natural Smoc‐protected Amino Acids Is Described, As Well As The Assembly Of 22 Peptide Sequences And The Fundamental Issues Of Spps, Including The Protecting Group