CAS: 100-37-8; Diethylethanolamine

该化合物是一种有机化合物,被归类为alkanolamine,其特征为分子结构,包括两个乙基组和乙醇胺混合物,使其成为第三级矿物质;该化合物一般是无色的,淡黄色的,具有典型的矿物质味;它具有湿味,可以吸收空气中的水分,并且可以溶于水和各种有机溶剂;二乙基乙醇胺主要用于生产表面活性剂,乳化剂和腐蚀抑制剂;此外,它作为合成其他化学化合物的一个建筑块,用于个人护理产品和药品的配制;由于其矿物质功能,它可以参与各种化学反应,包括通融和细胞反应;安全考虑包括谨慎处理它,因为它可能刺激皮肤和眼睛,因此在处置过程中应当使用适当的个人防护设备.

结构式图片

欧盟法规

统一分类与标签压力设备指令-第1组危险流体REACH注册ECHA物质欧盟气雾剂指令-标签制度ECHA物质工作场所安全标识要求C&L通报REACH预注册废弃物危险特性清单

上下游产品

oxirane diethylamine carbonic acid ethyl ester-(2-diethylamino-ethyl ester) diethyl sulfate2-[2-(diethylamino)ethoxy] ethanol acetaldehyde diethylamine 2-(Ethylamino)ethanol

合成工艺路线路线简述

    盐酸普鲁卡因置于水,Sodium Dodecyl-Sulfate,Sodium Hydroxide体系中,化学反应生成二乙氨基乙醇
    参考文献:普鲁卡因在水和胶束介质中水解的动力学
    标题:普鲁卡因在水和胶束介质中水解的动力学
    摘要:普鲁卡因的碱性水解的伪一阶条件下的动力学([oh-]»[普鲁卡因])已被进行.N,N-二乙基氨基乙醇和p获得了氨基苯甲酸根阴离子作为水解产物.发现水解速率与[naoh]线性相关.阳离子十六烷基三甲基溴化铵(ctab),十二烷基三甲基溴化铵(ddtab)和十四烷基三甲基溴化铵以及阴离子十二烷基硫酸钠(sds)胶束的加入均抑制了水解速率.Sds胶束对反应速率的抑制作用最大,而阳离子表面活性剂中ctab抑制作用最大.胶束介质中普鲁卡因水解速率的变化归因于反应分子对表面活性剂的取向以及普鲁卡因与胶束的结合常数.在dtbab胶束中普鲁卡因的水解速率可忽略不计.基于假相离子交换模型对存在阳离子胶束的观察结果进行了处理.用假相模型处理在阴离子胶束存在下获得的结果,并确定各种动力学参数.©2012 Wiley Periodicals,Inc.国际化学杂志kinet 45:1-9,2013
    Doi:10.1002/kin.20735

    专利信息


    专利号:US-6540970-B1
    优先权日:1999-11-18
    标题:Method for the synthesis of molecular sieves
    发明人:STROHMAIER KARL G; VAUGHAN DAVID E W
    权利人:EXXON MOBIL CHEM PATENTS INC
    摘要:The present invention provides a method for the synthesis of MeAPO molecular sieves which includes the following steps: providing a source of alumina, a source of phosphorus, water, and a template suitable for forming a MeAPO molecular sieve; providing a source of metal (Me) including metal particles, the metal particles measuring, in their largest dimension, equal to or less than five nanometers; providing a water soluble organic solvent capable of solubilizing the source of metal; forming a synthesis mixture from the source of alumina, the source of phosphorus, the water, the template, the source of metal, and the solvent; and forming a MeAPO molecular sieve from the synthesis mixture.

    专利号:US-7825244-B2
    优先权日:2005-06-10
    标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
    发明人:BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
    权利人:JANSSEN PHARMACEUTICA NV
    摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

    专利号:US-9126196-B2
    优先权日:2009-05-26
    标题 :Composition including dialkyl tin oxide and use thereof as a transesterification catalyst for the synthesis of (meth) acrylic esters
    发明人:PAUL JEAN-MICHEL; TONNELIER BORIS; AUGUSTIN FRANCIS
    权利人:PAUL JEAN-MICHEL; TONNELIER BORIS; AUGUSTIN FRANCIS; ARKEMA FRANCE
    摘要:The present invention relates to a composition including a dialkyl tin oxide, such as DBTO, which can be used as a transesterification catalyst for the synthesis of (meth)acrylic esters. The invention also relates to a method for the synthesis of (meth)acrylic esters by transesterification in the presence of said composition.

    专利号:US-6156547-A
    优先权日:1990-04-16
    标 题:Apparatus for the synthesis of saccharide compositions
    发明人:ROTH STEPHEN
    权利人:NEOSE PHARM INC
    摘要:This invention relates to an apparatus containing specific binary combinations of glycosyltransferases, for the synthesis of specific saccharide compositions such as, for example, oligosaccharides, polysaccharides, glycolipids, and glycopeptides.

    专利号:US-7435861-B2
    优先权日:2005-04-29
    标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
    发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
    权利人:CARDAX PHARMACEUTICALS INC
    摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

    专利号:US-2008221377-A1
    优先权日:2006-06-16
    标题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
    发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
    权利人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L
    摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
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    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 302.
    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 94.
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    摘要:Journal of Industrial Hygiene and Toxicology., 26(269), 1944
    摘要:Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA10 8
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