CAS: 4664-16-8; 6-Hydroxy-4-Methylpyridin-2(1H)-One

该化合物是属于丙烯酮类的环环有机化合物,具有氢氧化物组和特定位置的甲基组,具有独特的化学特性,典型特征是能够形成金属离子的切合层,使其对协调化学和药物及农业的潜在应用感兴趣,在极地溶剂中表现出中等溶性,受到氢氧基组的存在影响,该化合物可参与各种化学反应,包括自动消化,这种反应可视环境的pH的不同形式存在.此外,已经对其生物活动进行了6-Hydroxy-4-甲基-2-丙烯酮的研究,包括抗微生物菌和抗氧化物特性,其结构特征和再活动使其成为有机合成和药化学研究的宝贵化合物.

结构式图片

相似化合物

10357-84-3 99-11-6 22385-36-0

上下游产品

2,6-dihydroxy-3-cyano-4-methylpyrimidine 2,6-bis-benzyloxy-4-methyl-pyridine 2-amino-6-hydroxy-4-methyl-nicotinic acid amide 2,6-dihydroxy-4-methyl-nicotinic acid amide 2,6-dichloro-4-picoline 2,6-Dibromo-4-methylpyridine 4'-methyl-2,2':6',2''-terpyridine 4,4',4-trimethyl-2,2':6',2-terpyridine

合成工艺路线路线简述

    2-氨基-4-甲基-6-氧代-1H-吡啶-3-甲酰胺置于硫酸体系中,化学反应生成 2,6-二羟基-4-甲基吡啶
    参考文献:[2-Ami基乙酰胺与β-二羰基化合物的缩合.含氮杂环的合成.ix ..].
    标题:[2-Ami基乙酰胺与β-二羰基化合物的缩合.含氮杂环的合成.ix ..].
    摘要:
    DOI:10.1002/ardp.19542870703

    海关参考信息

    专利信息


    专利号:US-6306179-B1
    优先权日:1997-10-22
    标题:Method for the synthesis of 2-hydroxyalkyl-para-phenylenediamines, new 2-hydroxyalkyl-para-phenylenediamines, their use for oxidation dyeing, dyeing compositions and methods of dyeing
    发明人:GENET ALAIN; LAGRANGE ALAIN
    权利人:OREAL
    摘要:The present invention relates to a new method for the synthesis of 2-hydroxyalkyl-para-phenylenediamines which are substituted or unsubstituted at the 5-position of the benzene ring, new 2-hydroxyalkyl-para-phenylenediamines which are substituted or unsubstituted at the 5-position of the benzene ring, their use for the oxidation dyeing of keratinous fibers, the dyeing compositions containing them, as well as the methods of dyeing using them.

    专利号:US-5700939-A
    优先权日:1993-06-10
    标题:Intermediates useful in camptothecin synthesis
    发明人:FORTUNAK JOSEPH
    权利人:SMITHKLINE BEECHAM CORP
    摘要:The present invention provides a process for the asymmetric synthesis of camptothecin analogues as well as novel chemical intermediates of Formula I, II, and III. In general, the present process comprises conversion of a cis dioxolanone, having the same desired absolute configuration as the desired camptothecin analogue, to a compound of Formula I, II, or III, which compound is then converted to the desired camptothecin analogue. ##STR1##

    专利号:WO-9108265-A1
    优先权日:1989-12-02
    标 题:Azo compounds and their use as dyes, 1-sulpho-6-carboxyl-amino naphthaline, its use as a diazo component and process for the production of these compounds
    发明人:SPRINGER HARTMUT; HUSSONG KURT
    权利人:HOECHST AG
    摘要:The description relates to azo compounds corresponding to formula (1) below, having fibre-reactive properties and making valuable dyes. They can dye hydroxy and/or carbonamide group-containing synthetic and natural materials, especially fibre materials, like wool and especially cellulose fibre materials in bright colours. Formula (1) in which: M is hydrogen or a salt-forming metal like an alkaline metal; K is a residue of general formulae (2A) or (2B) in which: E is the residue of an intermediate component common in disazo dyes which can act as a coupling and as a diazo component, e.g. the residue of a 1-(aminophenyl) or -amino-naphthyl) pyrazolon, aminonaphthol, anilin or 1-amino naphthalin compound; v is the figure zero or 1; K is the residue of a water-soluble coupling component, preferably from the naphthol, aminonaphthol, anilin, pyrazolon, hydroxypyridon and acetoacetyl arylide series, whereby this coupling component contains 1 or 2 fibre-reactive groups of the vinyl sulphonate series; D is a benzol or naphthalin residue, whereby its substituents R?1 and R?2 are common ones in azo dyes, e.g. (besides hydrogen) lower alkyl, lower alkoxy, halogen, sulpho and carboxyl; the group -SO2?-Y is a fibre-reactive group of the vinyl sulphone series; a is the figure zero, 1 or 2; and k is the number 1 or 2. A description is also given of the compound 2-amino naphthaline-1-sulphonic acid-6-carboxylic acid which may be used as a pre-product in the production of dyes, e.g. as diazo component in the synthesis of dyes of general formula (1).

    专利号:US-4665222-A
    优先权日:1980-01-31
    标题 :Production of ethylene glycol from synthesis gas
    发明人:WHYMAN ROBIN
    权利人:ICI LTD
    摘要:A process for the production of ethylene glycol, methanol, ethanol and/or esters thereof from mixtures of carbon monoxide and hydrogen (synthesis gas) which comprises contacting a mixture of carbon monoxide and hydrogen with a catalyst at elevated pressure in a liquid medium, said catalyst comprising ruthenium and at least one other metal from Group VIII of the Periodic Table, and wherein the molar proportion of ruthenium is at least 50 percent relative to the other Group VIII metals. The process is particularly applicable to the selective production of ethylene glycol. The preferred catalysts, which comprise ruthenium/rhodium, may be present in elemental form, as coordination compounds or salts, e.g. carbonyls, acetyl acetonates or carboxylates. It is especially preferred to use a co-catalyst comprising a compound of one or more the metals of Groups IA, IIA or IIB or a nitrogen containing cation and/or base. Suitable liquid media include carboxylic acids (e.g. acetic acid) and ethers (e.g. tetraglyme).

    专利号:JP-H08511539-A
    优先权日:1993-06-10
    标 题:Asymmetric Total Synthesis of Camptothecin Analogs

    专利号:EP-0705262-A1
    优先权日:1993-06-10
    标 题:Process for asymmetric total synthesis of camptothecin
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