CAS: 35166-78-0; Magnesium,Methanidylcyclohexane,Bromide

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专利信息

专利号:US-5856497-A
优先权日:1995-12-11
标题 :Asymmetric synthesis of α-cycloalkylalkyl substituted methanamines
发明人：ROTH GREGORY; LANDI JOHN
权利人:BOEHRINGER INGELHEIM PHARMA
摘要:This invention relates to process for asymmetrically producing enantiomerically pure α-cycloalkylalkyl substitututed methanamines from α-pinene. One key step of the process of this invention utilizes the oxidation product of α-pinene, hydroxy pinanone, as a chiral auxiliary to direct the stereoselective alkylation of the corresponding ketimine. This invention also relates to key intermediates useful in the processes referred to herein.

专利号:JP-H10502059-A
优先权日:1994-06-17
标 题 :Synthesis of condurit epoxides and aziridines and their use in the synthesis of advanced disaccharides

专利号:EP-0781750-A2
优先权日:1995-12-11
标 题:Asymmetric synthesis of alpha-cycloalkylalkyl substituted methanamines

专利号:US-11267824-B2
优先权日:2017-08-17
标 题:Inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan 2,3-dioxygenase
发明人：BOSS CHRISTOPH; BUR DANIEL; CREN SYLVAINE; KIMMERLIN THIERRY; LOTZ-JENNE CARINA; POTHIER JULIEN; TIDTEN-LUKSCH NAOMI
权利人:IDORSIA PHARMACEUTICALS LTD
摘要:The present invention relates to compounds of Formula (I) inhibiting indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) enzymes. Further, their synthesis and their use as medicaments in inter alia cancer is disclosed.

专利号:CA-2192417-A1
优先权日:1995-12-11
标 题:Asymmetric synthesis of ó-cycloalkylalkyl substituted methanamines

专利号:JP-H09221472-A
优先权日:1995-12-11
标题:Asymmetric synthesis of alpha-cycloalkyl-substituted methanamines