对三氟甲基苯甲醛置于二异丁胺,磺酰氯,间氯过氧苯甲酸体系中,化学反应生成3-氯-4-羟基三氟甲苯 参考文献:(2R)-2-Methylchromane-2-Carboxylic Acids: Discovery Of Selective Pparα Agonists As Hypolipidemic Agents 标题:(2R)-2-Methylchromane-2-Carboxylic Acids: Discovery Of Selective Pparα Agonists As Hypolipidemic Agents 摘要:A Sar Study Was Conducted On Chromane-2-Carboxylic Acid Toward Selective Ppar Alpha Agonisim. As A Result,Highly Potent,And Selective Ppar Alpha Agonists Were Discovered. The Optimized Compound 43 Exhibited Robust Lowering Of Total Cholesterol Levels In Hamster And Dog Animal Models. (C) 2005 Elsevier Ltd. All Rights Reserved. Doi:10.1016/j.Bmcl.2005.05.028
专利号:US-4402804-A 优先权日:1982-05-17 标题 :Electrolytic synthesis of aryl alcohols, aryl aldehydes, and aryl acids 发明人:JACKSON PATRICIA J 权利人:PPG INDUSTRIES INC 摘要:Disclosed is a method of synthesizing compounds chosen from the group consisting of benzyl alcohol, benzaldehyde, benzoic acid, phenoxy benzyl alcohol, phenoxy benzaldehyde, phenoxy benzoic acid, and mixtures thereof by providing a composition of a current carrying component, such as a fluoroborate salt or a tetraethylammonium salt, a solvent, and a methyl aryl compound in contact with an anode and cathode. The solvent is reduced at the cathode and the methyl substituted aryl at the anode whereby to form product. According to an alternative exemplification of the invention, the anode and cathode are separated by a permionic membrane and a source of oxygen is provided in contact with the cathode and the permionic membrane.
专利号:US-4450308-A 优先权日:1980-02-08 标 题:Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds 发明人:FOERSTER HEINZ; PRIESNITZ UWE 权利人:BAYER AG 摘要:New process for the preparation of known trifluoromethylphenyl oxyphenyl ether compounds of the formula ##STR1## wherein X stands for fluorine, chlorine or bromine and n R for moieties, substituted if desired, of the series alkyl, alkenyl and alkinyl, n by reacting 1,2-dihalogen-4-trifluoromethylbenzenes of the formula ##STR2## in which X and X 1 independently of one another stand for fluorine, chlorine or bromine, n with phenols of the formula ##STR3## in which R has the meaning given above, and basic alkali or alkaline earth compounds or with the salts formed from the phenols of formula (III) and the basic alkali or alkaline earth compounds, in the presence of diluents at temperatures between 60° and 120° C. n The compounds of the formula (I) are intermediates for the synthesis of herbicides.
专利号:US-4621160-A 优先权日:1983-06-23 标题 :Process for the chlorination of aromatic derivatives 发明人:DESBOIS MICHEL; DISDIER CAMILLE 权利人:RHONE POULENC SPEC CHIM 摘要:A process for the chlorination of aromatic derivatives. The aromatic derivative is reacted with chlorine gas in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.
专利号:CN-110357773-A 优先权日:2019-07-08 标题 :Synthesis of 3-chloro-4-hydroxybenzoic acid
专利号:CN-102030655-B 优先权日:2010-10-21 标题:Synthesis method of diphenyl ether derivate, combined production method of oxyfluorfen and acifluorfen and synthesis method of oxyfluorfen
专利号:CN-102030655-A 优先权日:2010-10-21 标题 :Synthesis method of diphenyl ether derivate, combined production method of oxyfluorfen and acifluorfen and synthesis method of oxyfluorfen
参考标题:Cascade Palladium Catalysis: A Predictable And Selectable Regiocontrolled Synthesis OfN-Arylbenzimidazoles 作者:Nathan T. Jui,Stephen L. Buchwald |发布日期:2013.10.25 摘要:Choice: The Palladium‐catalyzed Cascade Reaction Of 2‐chloroaryl Sulfonates With Arylamine And Amide Nucleophiles Provides Direct Access To N‐arylbenzimidazoles. This Strategy Selectively Produces The Heterocycles Based On Chemoselective Oxidative Addition. 2‐chloroaryl Triflates (Tf) Produce One Regioisomer And The Corresponding 2‐chloroaryl Mesylates (Ms) Deliver The Other In A Selectable Manner.
合成参考文献
参考文献:10.1007/s40003-024-00740-8 摘要:Majid S, Ahmad KS, Malik MA, Karami AM. Exploring Oxyfluorfen's Environmental Fate: Soil Affinity, Persistence, Degradation Dynamics and Ecological Implications. Agric Res. 2024 Aug 02;13(4):763–78. doi: 10.1007/s40003-024-00740-8.