CAS: 135112-27-5; Fmoc-Abu-Oh

相似化合物

170642-27-0 1492-24-6 2623-91-8

上下游产品

Fm°C-Abu-MFE L-2-aminobutyric acid N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

L-2-氨基丁酸,9-芴甲基-N-琥珀酰亚胺基碳酸酯置于sodium Carbonate体系中,用 1,4-二氧六环,水 用作溶剂,化学反应 18.0H,反应生成N-芴甲氧羰基-L-2-氨基丁酸
参考文献:真菌双加氧酶asqj是混杂的且是双峰的:喹诺酮类与喹唑啉酮类的底物定向形成
标题:真菌双加氧酶asqj是混杂的且是双峰的:喹诺酮类与喹唑啉酮类的底物定向形成
摘要:先前的研究表明,Fe Ii /α-酮戊二酸依赖性双加氧酶asqj诱导构巢曲霉在viridicatin生物合成中的骨架重排,从苯并[1,4]二氮杂-2,5-二酮底物生成喹诺酮骨架.我们报告说,仅通过改变苯并二氮杂二酮底物中的取代基,Asqj即可催化另外的,完全不同的反应.通过底物筛选,功能探针的应用和计算分析来建立这种新机制.Asqj消费税h 2由合适的苯并[1,4]二氮杂-2-5,5-二酮底物的杂环结构生成co,生成喹唑啉酮.这种新颖的asqj催化途径由复杂底物中的单个取代基控制.Asqj的这种独特的底物定向反应性可实现喹诺酮或喹唑啉酮的靶向生物催化生成,喹诺酮或喹唑啉酮是两种具有特殊生物医学相关性的生物碱框架.
Doi:10.1002/anie.202017086

专利信息

专利号:US-9475837-B2
优先权日:2011-12-23
标题 :Process for the synthesis of therapeutic peptides
发明人：HURLEY FIONN; WEGNER KATARZYNA; FOLEY PATRICK
权利人:IPSEN MFG IRELAND LTD
摘要:The present invention relates to a process for the large-scale synthesis of therapeutic peptides using a Sieber Amide resin, which comprises solid-phase Fmoc-chemistry.

专利号:US-2002012912-A1
优先权日:1999-05-25
标题 :Parallel combinatorial libraries for chiral selectors
发明人：LI TINGYU; HARRIS THOMAS M; WANG YAN
摘要:A method to screen parallel combinatorial libraries for chiral selectors, for instance, a parallel library screening procedure demonstrating the chiral resolution of racemic analyte such as racemic (1-naphthyl)leucine ester. The method involves synthesis of potential chiral selectors on polymeric synthesis resins and the rapid screening of selectors directly on the resins with batch incubation, followed by circular dichroism measurement. The method does not require pre-immobilization of the analyte. The identified chiral selector is then attached onto a support and employed to resolve the racemic analyte into its R-enantiomer and S-enantiomer.

专利号:US-2024287106-A1
优先权日:2021-06-09
标题 :Method for Producing Fluorescent Probe Library Using Solid-Phase Extraction and Method of Measuring Enzyme Activity Using Same
发明人：KOMATSU TORU; URANO YASUTERU; SAKAMOTO SHINGO; WATANABE RIKIYA; KAGAMI YU
权利人:UNIV TOKYO; RIKEN
摘要:To provide a synthesis scheme capable of easily synthesizing various kinds of fluorescent probes. A method for preparing a compound represented by Formula (III) below, the method including steps (1) to (5).

专利号:JP-6192657-B2
优先权日:2011-12-23
标 题 :Method for the synthesis of therapeutic peptides

专利号:US-2015045534-A1
优先权日:2011-12-23
标题:Process for the Synthesis of Therapeutic Peptides

专利号:US-2017137489-A1
优先权日:2011-12-23
标题 :Process for the Synthesis of Therapeutic Peptides