CAS: 2642-63-9; 1-(3,4-Dichlorophenyl)Ethanone

上下游产品

3-amino-4-chloroacetophenone 1-(3,4-dichlorophenyl)ethan-1-ol 1-(2-amino-4-chloro-3-nitro-phenyl)-ethanone 1-(2-amino-4-chloro-5-nitro-phenyl)-ethanone 2-(3,4-dichlorophenyl)quinoline-4-carboxylic acid (2E)-1-(3,4-dichlorophenyl)-3-phenyl-2-propen-1-one 1-(3,4-dichlorophenyl)ethan-1-ol 2-(3,4-dichloro-phenyl)-but-3-yn-2-ol

1-(2-氨基-4-氯苯基)乙酮置于盐酸,硫酸,硝酸体系中,化学反应生成3,4-二氯苯乙酮
参考文献:54.五线谱.第十部分.4-氯-2-氨基苯乙酮及相关的4-羟基苯二酚的制备
标题:54.五线谱.第十部分.4-氯-2-氨基苯乙酮及相关的4-羟基苯二酚的制备
摘要:
Doi:10.1039/jr9470000232

专利信息

专利号:US-4453012-A
优先权日:1982-04-22
标 题 :Process for the preparation of phenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of phenyl ketones, characterized in that, in a first stage, a halo- or trihalomethylbenzene is reacted with a trihalomethylated aliphatic or aromatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent, and in that, in a second stage, the resultant product is hydrolyzed. The products are used as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

专利号:US-5138088-A
优先权日:1988-06-17
标 题 :Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof
发明人：KIM YOU SEUNG; PARK SANG WOO; KIM JEA CHEOL
权利人:KOREA ADVANCED INST SCI & TECH
摘要:Nitrobenzoyl-3-cyclopropylaminoacrylates are prepared by two stage reaction: a) The first stage is the synthesis of nitrobenzoyl-3-alkoxyacrylates from nitrobenzoylester compound and alkylorthoformate in organic acid solvent. b) The second stage is the synthesis of nitrobenzoyl-3-cyclo propylamino acrylate from nitrobenzoyl-3-alkoxyacrylates and cyclopropylamine.

专利号:US-6005103-A
优先权日:1993-11-19
标题 :Pyrone derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

专利号:WO-2023086799-A1
优先权日:2021-11-09
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists
发明人：HOUZE JONATHAN B; PANDYA BHAUMIK; KAPLAN ALAN P
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 ('TREM2'). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-4656267-A
优先权日:1983-09-29
标题 :Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
发明人：BANDURCO VICTOR T; LEVINE SEYMOUR D; MULVEY DENNIS M; TOBIA ALFONSO J
权利人:ORTHO PHARMA CORP
摘要:The synthesis of substituted 2(1H)-quinazolinone-1-alkanoic acids and their esters is described. The novel quinazolinones are renal vasodilators and as such reduce vascular resistance to renal blood flow. The quinazolinones are useful as cardiovascular agents.

专利号:EP-0729465-B1
优先权日:1993-11-19
标 题:Pyrone derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:PARKE DAVIS & CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.