CAS: 28789-35-7; N-(4-Hydroxy-3-Methoxybenzyl)-7-Methyloctanamide

该化合物是辣椒中的一种类比骨灰素,在结构上类似于二氢海扁椒,但有较短的烷基侧链,它表现出作为挥发性受体(TRPV1)的刺激剂的生物活性,尽管与冠尾素相比,其威力略有降低,该化合物主要用于研究TRPV1 介质的生理反应,包括疼痛感知和温度调控,其中度柔软性和独特的结合性使与其他辣椒类进行比较研究具有价值.诺迪海藻赛门素也用于...

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CAS号112375-60-7 (Z)-N-[(4-hydro... | CAS号61229-08-1 norcapsaicin | CAS号1196-92-5 4-(氨基甲基)-2-甲氧基苯酚 | CAS号6026-86-4 5-氧代戊酸甲酯 | CAS号14273-92-8 5-羟基戊酸甲酯 | CAS号61229-06-9 (E)-7-methyl°Ct... | CAS号81077-23-8 (Z)-7-methyl°Ct... | CAS号112375-57-2 (E)-7-methyl°Ct... | CAS号112375-41-4 methyl (Z)-7-me... | CAS号112375-53-8 methyl (E)-7-me...

合成工艺路线路线简述

    5-羟基戊酸甲酯置于palladium On Activated Charcoal 甲醇,氢氧化钾,氯化亚砜,Sodium Amalgam,氢气,Sodium Acetate,Pyridinium Chlorochromate体系中,用 四氢呋喃,乙醚,乙醇,二氯甲烷 用作溶剂,-20.0~100.0 °C,101.33 Kpa 条件下,反应 105.0H,反应生成降二氢辣椒碱
    参考文献:Capsaicinoids: Their Separation,Synthesis,And Mutagenicity
    标题:Capsaicinoids: Their Separation,Synthesis,And Mutagenicity
    摘要:
    Doi:10.1021/jo00240A024

    海关参考信息

    专利信息


    专利号:US-12071646-B2
    优先权日:2014-09-11
    标 题 :Cells comprising mogroside pathway enzymes and uses thereof
    发明人:ITKIN MAXIM; DAVIDOVICH-RIKANATI RACHEL; COHEN SHAHAR; PORTNOY VITALY; DORON-FAIGENBOIM ADI; PETREIKOV MARINA; SHEN SHMUEL; TADMOR YAAKOV; BURGER YOSEF; LEWINSOHN EFRAIM; KATZIR NURIT; SCHAFFER ARTHUR A; OREN ELAD
    权利人:THE STATE OF ISRAEL MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT AGRICULTURAL RES ORGANIZATION ARO VO
    摘要:Isolated mogroside and mogrol biosynthetic pathway enzyme polypeptides useful in mogroside biosynthesis are provided. Mogroside biosynthetic pathway enzymes of the invention include squalene epoxidase (SE), epoxy hydratase (EH), cytochrome p450 (Cyp), cucurbitadienol synthase (CDS) and udp-glucosyl-transferase (UGT), Also provided are methods of producing a mogroside using the isolated mogroside and mogrol biosynthetic enzyme polypeptides, the methods comprising contacting a mogrol and/or a glycosylated mogrol (mogroside) with at least one UDP glucose glucosyl transferase (UGT) enzyme polypeptide of the invention catalyzing glucosylation of the mogrol and/or the glucosylated mogrol to produce a mogroside with an additional glucosyl moietie(s), thereby producing the mogroside. Alternatively or additionally provided is a method of synthesizing a mogrol, the method comprising contacting a mogrol precursor substrate with one or more mogrol biosynthetic pathway enzyme polypeptides as described herein catalyzing mogrol synthesis from the mogrol precursor substrate, thereby synthesizing the mogrol.

    专利号:FR-3100955-A1
    优先权日:2019-09-24
    标题:CONTROLLED ELICITATION PROCESS OF CHILI PLANTS DURING THEIR CULTURE TO INCREASE THEIR SYNTHESIS OF SECONDARY METABOLITES OF INDUSTRIAL INTEREST

    专利号:WO-2021058410-A1
    优先权日:2019-09-24
    标 题:Method for controlled elicitation of pepper plants under cultivation to increase their synthesis of secondary metabolites of industrial interest

    专利号:EP-4033887-A1
    优先权日:2019-09-24
    标题:Method for controlled elicitation of pepper plants under cultivation to increase their synthesis of secondary metabolites of industrial interest

    专利号:US-2010256413-A1
    优先权日:2007-04-24
    标题:Method for the chemical synthesis of capsinoids

    专利号:EP-2149548-A1
    优先权日:2007-04-24
    标 题 :Method for the chemical synthesis of capsinoids
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    主要参考文献


    1: Yap ESP, Uthairatanakij A, Laohakunjit N, Jitareerat P, Vaswani A, Magana AA, Morre J, Maier CS. Plant growth and metabolic changes in 'Super Hot' chili fruit (Capsicum annuum) exposed to supplemental LED lights. Plant Sci. 2021 Apr;305:110826. doi: 10.1016/j.plantsci.2021.110826. Epub 2021 Jan 14. 24(2):219-226. doi: 10.3923/pjbs.2021.219.226.
    338:128012. doi: 10.1016/j.foodchem.2020.128012. Epub 2020 Sep 6. 236(6):1863-1874. doi: 10.1007/s00213-019-5170-2. Epub 2019 Jan 29. 34(11):1597-1601. doi: 10.1080/14786419.2018.1519821. Epub 2018 Nov 17. 35(8):1447-1452. doi: 10.1080/19440049.2018.1457801. Epub 2018 Jul 12.
    239:217-224. doi: 10.1016/j.foodchem.2017.06.098. Epub 2017 Jun 20. 22(5):736. doi: 10.3390/molecules22050736.

    合成参考文献


    参考文献:10.1080/03601230600701908
    摘要:ANTONIOUS G, JARRET R. Screening Capsicum Accessions for Capsaicinoids Content. Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes. 2006 Jun 01;41(5):717–29. doi: 10.1080/03601230600701908.
    参考文献:10.1007/s00424-008-0527-0
    摘要:Ianowski JP, Choi JY, Wine JJ, Hanrahan JW. Substance P stimulates CFTR-dependent fluid secretion by mouse tracheal submucosal glands. Pflügers Archiv - European Journal of Physiology. 2008 May 29;457(2):529. doi: 10.1007/s00424-008-0527-0.
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