专利号:US-9873905-B2 优先权日:2014-03-07 标题:Chemoenzymatic synthesis of trehalose analogs 发明人:SWARTS BENJAMIN M; WOODRUFF PETER 权利人:CENTRAL MICHIGAN UNIV; UNIV OF MAINE SYSTEM 摘要:The present invention provides methods of synthesizing trehalose analogs; methods of detecting mycobacteria, and trehalose analogs.
专利号:US-6319695-B1 优先权日:1991-10-15 标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose 发明人:WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN 权利人:SCRIPPS RES INSITUTE 摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.
专利号:EP-1789107-B1 优先权日:2004-08-30 标题 :Medical stent provided with inhibitors of atp synthesis 发明人:POPOWSKI YOURI 权利人:INTERSTITIAL THERAPEUTICS 摘要:The present invention relates to a stent provided with a composition comprising at least one type of inhibitor of ATP synthesis optionally together with at least one inhibitor of the pentose phosphate pathway (PPP) for use in treating stenosis and preventing restenosis in vascular ducts, and for use in treating cancerous tumours present in ducts, resectioned cavities and scars, and for use in treating any disorder arising from the proliferation of cells in ducts or cavities.
专利号:US-2015252402-A1 优先权日:2014-03-07 标 题 :Chemoenzymatic Synthesis of Trehalose Analogs
专利号:US-4301276-A 优先权日:1980-03-07 标题:Synthesis of daunosamine hydrochloride and intermediates used in its preparation 发明人:WHISTLER ROY L 权利人:PURDUE UNIVERSITY 摘要:A process for synthesizing daunosamine hydrochloride is disclosed. Intermediates useful for synthesizing daunosamine hydrochloride, and processes for preparing such intermediates, are also disclosed.
专利号:US-11879147-B2 优先权日:2014-03-07 标 题:Chemoenzymatic synthesis of trehalose analogues
摘要:Schafer, E. W., Jr., W. A. Bowles Jr., and J. Hurlbut. 1983. The acute oral toxicity and repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds. Archives of Environmental Contamination and Toxicology 12:355-382. 摘要:Schafer, E.W., Jr., et al. 1982. Effects of 77 chemicals on reproduction in male and female coturnix quail. Ecotox. Environ. Safety 6:149-156 参考文献:10.1007/s00213-002-1022-5 摘要:Williams DL, Grill HJ, Weiss SM, Baird JP, Kaplan JM. Behavioral processes underlying the intake suppressive effects of melanocortin 3/4 receptor activation in the rat. Psychopharmacology (Berl). 2002 Apr;161(1):47–53. doi: 10.1007/s00213-002-1022-5. 参考文献:10.1002/dev.20145 摘要:Smith GP. Ontogeny of ingestive behavior. Dev Psychobiol. 2006 Jul;48(5):345–59. doi: 10.1002/dev.20145. 参考文献:10.1007/s10295-014-1455-y 摘要:Wang C, Cai H, Zhou Z, Zhang K, Chen Z, Chen Y, Wan H, Ouyang P. Investigation of ptsG gene in response to xylose utilization in Corynebacterium glutamicum. Journal of Industrial Microbiology & Biotechnology. 2014 May 25;41(8):1249–58. doi: 10.1007/s10295-014-1455-y.