CAS: 85-55-2; 2-(P-Toluoyl)Benzoic Acid

该化合物是一种有机化合物,其芳香结构特征包括两个苯环,由碳基组和一个碳基酸功能组连接,该化合物一般是白色的,白线的晶体固体,在有机合成领域的应用和聚合化学中的光化剂.一个苯环上的甲基组影响其溶性和再活性,使其在各种化学反应中发挥作用.该化合物在标准条件下一般稳定,但在接触强酸或碱时可能会降解.其熔点和溶性可能因使用的溶剂而不同.安全数据表明,应当谨慎处理,因为接触皮肤或眼睛时可能会引起刺激.

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CAS号85-44-9 苯酐 | CAS号108-88-3 甲苯 | CAS号7163-50-0 (4-甲基苯基)(氧代)乙酸 | CAS号65-85-0 苯甲酸 | CAS号4397-55-1 2-氯甲酰基苯甲酸甲酯 | CAS号20754-20-5 对甲基肉桂酸甲酯 | CAS号13740-73-3 2-[4-Sulfamoyl-... | CAS号13304-46-6 2-phenyl-3-(p-t... | CAS号80764-40-5 (2-(4,4-dimethy... | CAS号51334-85-1 (4-甲基苯基)-1-(2H)-酞嗪酮 | CAS号84-54-8 2-甲基蒽醌 | CAS号28864-65-5 3,3-bis(4-methy... | CAS号85-58-5 苯甲酮-2,4'-二甲酸一水合物 | CAS号134-84-9 4-甲基二苯甲酮 | CAS号613-12-7 2-甲基蒽 | CAS号15254-27-0 2-(3-Chloro-4-m... | CAS号15247-71-9 2-(4-methyl-3-n... | CAS号15247-73-1 2-(3-amino-4-me... | CAS号99-94-5 对甲基苯甲酸

合成工艺路线路线简述

    2-Phenyl-3-P-Tolyl-Inden-1-On置于氯磺酸,Ammonium Hydroxide,Potassium Permanganate体系中,用 氯仿,丙酮 作为反应溶剂,化学反应 3.0H,反应生成 2-(4-甲基苯甲酰)苯甲酸
    参考文献:ber Die Chlorsulfonierung Von Arylsubstituierten Indonen
    标题:ber Die Chlorsulfonierung Von Arylsubstituierten Indonen
    摘要:
    DOI:10.1007/bf00902604

    海关参考信息

    专利信息


    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-7002020-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:CN-110256221-B
    优先权日:2019-05-13
    标题:Synthesis method of 2-alkylanthraquinone

    专利号:CN-116730819-A
    优先权日:2023-02-02
    标题:A green synthesis method of ultrapure anthraquinone and 2-alkylanthraquinone
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    主要参考文献

    参考标题:Continuous-Flow Retro-Diels-Alder Reaction: A Process Window For Designing Heterocyclic Scaffolds
    作者:Imane Nekkaa,Márta Palkó,István M. Mándity,Ferenc Miklós,Ferenc Fülöp |发布日期:2018.8.31
    摘要:An Approach Based On A Highly Controlled Continuous‐flow (Cf) Retro‐diels-Alder Reaction Was Developed For The Synthesis Of New Compounds. Using This Approach, We Were Able To Rapidly Screen Reaction Conditions To Obtain The Desired Pyrimidinone Moieties In Short Reaction Times And High Yields. We Also Present An Alternative Route For The Synthesis Of Intermediates By Cf Cyclization.

    合成参考文献


    摘要:L. G. Bray, J. F. J. Dippy and S. R. C. Hughes, J. Chem. Soc. 1957, 265.
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