CAS: 98577-44-7; 1,1-Dibromo-2,2-Bis(Chloromethyl)Cyclopropane

相似化合物

71600-39-0 185320-50-7 67003-20-7

上下游产品

CAS号1871-57-4 3-氯-2-氯甲基丙烯 | CAS号75-25-2 三溴甲烷 | CAS号105542-98-1 1,3-二碘双环[1.1.1]戊烷 | CAS号107-25-5 乙烯基甲醚 | CAS号1120-56-5 亚甲基环丁烷 | CAS号311-75-1 bicyclo[1.1.1]p... | CAS号35634-10-7 Tricyclo[1.1.1....

3-氯-2-氯甲基丙烯 以70%的收率获得产物
参考文献:Della Ernest W.,Taylor Dennis K.,J. Org. Chem,59 (1994) N 11,S 2986-2996
标题:Della Ernest W.,Taylor Dennis K.,J. Org. Chem,59 (1994) N 11,S 2986-2996

专利信息

专利号:US-2024309003-A1
优先权日:2021-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：HOUZE JONATHAN B; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN; PANDYA BHAUMIK; KAPLAN ALAN
权利人:VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?). This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-12129228-B2
优先权日:2019-06-11
标题:Continuous synthesis method for 1, 1′-bicyclic [1.1.1]pentane-1,3-diethyl ketone compounds
发明人：HONG HAO; ZHANG ENXUAN; LU JIANGPING; WEI FULIANG; Yang sihang; CHE GUANDA
权利人:JILIN ASYMCHEM LABORATORIES CO LTD
摘要:Provided is a continuous synthesis method for 1,1′-bicyclic[1.1.1]pentane-1,3-diethyl ketone compounds. The continuous synthesis method comprises: under the irradiation of a light source, continuously conveying raw material A and raw material B to a continuous reaction device for a continuous photochemical reaction to obtain 1,1′-bicyclic[1.1.1]pentane-1,3-diethyl ketone compounds, and controlling the reaction temperature in the continuous reaction device by a temperature control device during the continuous photochemical reaction. A propellane with substituents, as a reaction raw material, is subjected to the above photochemical reaction in the continuous reaction device to reduce the probability of its slow decomposition and deterioration under the irradiation, and greatly improve the conversion rate of the reaction material and product yield.

专利号:US-10189780-B2
优先权日:2013-12-12
标题:Bicyclic alkyl compounds and synthesis
发明人：BUNKER KEVIN DUANE
权利人:KALYRA PHARMACEUTICALS INC; ZENO ROYALTIES & MILESTONES LLC
摘要:Disclosed herein are compounds of the general Formula (I), and methods of synthesizing a substituted bicyclo[1.1.1]pentane using a Group VII or Group IX transition metal compound.

专利号:WO-2020252661-A1
优先权日:2019-06-18
标题 :Method for continuous synthesis of propellane compounds

专利号:US-10654812-B2
优先权日:2014-03-07
标 题:Propellane derivates and synthesis
发明人：BUNKER KEVIN DUANE
权利人:KALYRA PHARMACEUTICALS INC; RECURIUM IP HOLDINGS LLC
摘要:Disclosed herein are compounds of the general Formula (I), and methods of synthesizing substituted bicyclo[1.1.1 jpentanes. The synthetic methods described herein use a [1.1.1]propellane, a Group VIII transition metal compound, a hydride source and a reagent that can contribute a substituent to form a substituted bicyclo[1.1.1]pentane, such as a compound of the general Formula (I).

专利号:EP-3988520-A1
优先权日:2019-06-18
标题 :Method for continuous synthesis of propellane compounds