CAS: 1004-38-2; 2,4,6-Triaminopyrimidine

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156-81-0 2434-56-2 2725790-86-1

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5-氯-嘧啶-2,4,6-三胺置于palladium On Activated Charcoal,Sodium Acetate,铂体系中,75.0 °C,5.88 Mpa 条件下,反应生成2,4,6-三氨基嘧啶
参考文献:Chloroaminopyrimidines
标题:Chloroaminopyrimidines
摘要:
Doi:10.1021/ja01165A504

专利信息

专利号:US-2005136439-A1
优先权日:2003-09-12
标题:Novel methods of inorganic compound discovery and synthesis
发明人：EATON BRUCE E; FELDHEIM DANIEL L; DOLSKA MAGDA; GUGLIOTTI LINA A
权利人:UNIV NORTH CAROLINA STATE
摘要:The present invention provides methods for the synthesis and/or discovery of inorganic compounds, including organometallic compounds. Also provided are functional nucleic acids for synthesis of inorganic compounds and methods of identifying the same. As another aspect, the invention provides compounds made according to the inventive methods, including palladium plates and cobalt-iron oxides spheres, cubes, fibers and nanotubes.

专利号:US-4686285-A
优先权日:1984-02-10
标题:Basic azo and non-azo compounds having one or two disubstituted 1,3,5-triazine rings each of which is linked through a bridging radical to the 1-position of a pyrazole ring
发明人：PEDRAZZI REINHARD
权利人:SANDOZ LTD
摘要:(i) Metal-free compounds of the formula ##STR1## (ii) tautomers thereof, (iii) 1:1 and 1:2 metal complexes of (i) and (ii), n (iv) salts of (i), (ii), and (iii), and n (v) mixtures of (i), (ii), (iii), and (iv), n wherein the symbols are as defined in the Specification, are useful as dyes for, for example, polymers and copolymers of acrylonitrile, polyesters modified to contain acid groups, polyamides such as wool, leather, cotton, bast fibers such as hemp, flax, sisal jute, coir and straw, regenerated cellulose, glass fibers and paper (those wherein R o is other than hydrogen) or as intermediates for the synthesis of dyes.

专利号:US-4167633-A
优先权日:1977-07-20
标题 :Preparation of 2,4,5,6-tetraaminopyrimidine from 2,4,6-triaminopyrimidine
发明人：MORROW THOMAS J
权利人:US HEALTH EDUCATION & WELFARE
摘要:An improved process for the production of ##STR1## FROM ##STR2## WHICH PRODUCES BUT DOES NOT ISOLATE AN INTERMEDIATE ##STR3## WHICH COMPOUND IS RETAINED IN SITU AND MINIMIZES THE COMPLEX POLYMER FORM OF A THREE-DIMENSIONAL NETWORK OF AZO LINKAGES FORMED BY THE NITROSO AND AMINO GROUPS. These groups, as they appear in the nitroso intermediate, have carcinogenic possibilities. It has been found that the nitroso compound will precipitate as a stirrable slurry if the temperature parameter is kept low at about 0°-20° C. A preferred route for the production of the nitroso compound from the triamino starting material utilizes as reactants 1.0-1.05 moles of sodium nitrite and 1.5 moles of HOAc in water (HCl may be substituted for HOAc). In the second state of this sequential reaction, the reduction of nitroso is carried out by a reducing agent and one preferred agent is sodium dithionite. Catalytic agents such as Raney nickel and hydrazine or nickel salts, e.g., nickel chloride, and sodium borohydride may also be used. The present process is an improvement in part of the technique of Piper and Montgomery, J. Het. Chem., 11:279 (1974), which process is designed specially to produce the antifolate methotrexate as an end product and is an improvement of the method of application Ser. No. 742,450 of Ellard filed Nov. 17, 1976, entitled 'Improved Synthesis of Methotrexate', U.S. Pat. No. 4,080,825.

专利号:US-10036007-B2
优先权日:2012-12-11
标题 :Method of synthesis of gene library using codon randomization and mutagenesis
发明人：BANG DUHEE; PARK SANGUN; LEE JOONGOO; LEE JEEWON
权利人:CELEMICS INC
摘要:Proposed is a method of easily finding an error during analysis of various library sequences of nucleic acid base sequences after synthesizing a gene library using a combination of three nucleic acid base sequences (codon) translated into the same protein. This shows that it is possible to create a gene library having the same protein sequence but different nucleic acid base sequences. The present disclosure provides a novel experimental method capable of measuring a correlation between gene expression according to change in a codon by changing the usage of a codon optimized to express a specific gene in vivo.

专利号:US-2006099589-A1
优先权日:2002-07-23
标题:Gene shuffling by template switching
发明人：PEDERSEN HENRIK; THISTED THOMAS; MOLLER HANS T
权利人:NUEVOLUTION AS
摘要:The present invention provides a new approach to creating novel polynucleotide sequences by point mutation and recombination in vitro of a set of parental sequences. The new polynucleotide sequences can be useful in themselves or they can be used for the templated synthesis of polymers, e.g. polypeptides composed of α-amino acids as occurring naturally in protein synthesis or polymers comprised of β-amino acids or other building blocks as described (Templated molecules).

专利号:US-2007059711-A1
优先权日:2004-07-30
标 题:Microarray for evaluation of stress-related genes in skin
发明人：SLOMINSKI ANDRZEJ; PISARCHIK ALEXANDER
权利人:SLOMINSKI ANDRZEJ; PISARCHIK ALEXANDER
摘要:The present invention provides a novel DNA microarray chip that can be used for simultaneous testing of transcriptional responses to cutaneous stressors in the context of neuro-endocrine-immune functions of the skin. The transcriptional responses to ultraviolet radiation in epidermal keratinocytes were tested using such microarray chip containing more than 700 neuro-endocrine-immune related genes. The gene expression pattern was non-random and time dependent; it included increased expression of genes involved in water and salt balance, prostaglandin synthesis, keratinocyte differentiation as well as genes coding for stress effectors, cytokines and metalloproteinases. In contrast, expression was decreased for genes coding for growth factors and their receptors, and for elements of extracellular matrix. This stochastic pattern suggests that transcriptional responses are coordinated and aimed at preservation of epidermal barrier function, prevention of early carcinogenic events and remodeling of extracellular matrix.