CAS: 14521-80-3; 3-Bromo-1H-Pyrazole

相似化合物

1448855-35-3 1260778-36-6 67460-86-0

上下游产品

CAS号500011-84-7 1-(二甲基氨基磺酰基)-3-溴吡唑 | CAS号78907-82-1 3-溴-4-三甲基硅烷基-1H-吡唑 | CAS号141791-06-2 5-(1,3-benzodio...

5-Bromo-1-(Phenylsulfonyl)-1H-Pyrazole置于sodium Hydroxide体系中,用 甲苯 用作溶剂,化学反应 1.0H,反应生成3-溴吡唑
参考文献: Methods For The Preparation Of 5-Bromo-2-(3-Chloro-Pyridin-2-yl)-2H-Pyrazole-3-Carboxylic Acid[fr] Procédés De Préparation D'Acide 5-Bromo-2-(3-Chloro-Pyridin-2-yl)-2H-Pyrazole-3-Carboxylique
标题: Methods For The Preparation Of 5-Bromo-2-(3-Chloro-Pyridin-2-yl)-2H-Pyrazole-3-Carboxylic Acid[fr] Procédés De Préparation D'Acide 5-Bromo-2-(3-Chloro-Pyridin-2-yl)-2H-Pyrazole-3-Carboxylique
摘要:本文描述了一种从吡唑或吡唑衍生物合成5-溴-2-(3-氯吡啶-2-基)-2H-吡唑-3-羧酸的新方法.同时还描述了新的反应中间体.

专利信息

专利号:US-11612614-B2
优先权日:2020-10-20
标题:Isomorphs of Remdesivir and methods for synthesis of same
发明人：TRIPATHI VINAY SHANKAR; PATEL AKSHAY NIKHIL
权利人:ANZALP PHARMASOLUTIONS PVT LTD
摘要:A new isoform of 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3/4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate (Remdesivir) having increased water solubility is disclosed, along with methods for making the same. Also disclosed are solid and liquid pharmaceutical compositions suitable for treating viral infections such as Arenaviridae, Coronaviridae, Filoviridae, Flaviviridae, or Paramyxoviridae viral infections which contain an effective amount of Remdesivir prepared according to the inventive method and the use of those compositions for treating such viral infections.

专利号:US-2009264648-A1
优先权日:2008-01-14
标题:Synthesis of pyrazoles
发明人：CHEW WARREN; WANG ZHENG; CHEAL GLORIA; BERTRAND MARTIAL; POTOSKI JOHN; MIRMEHRABI MAHMOUD; NENCINI ARIANNA; ZANALETTI RICCARDO
权利人:WYETH CORP; SIENA BIOTECH SPA
摘要:The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.

专利号:US-7034154-B2
优先权日:1999-08-10
标 题:Synthesis of substituted pyrazolopyrimidines
发明人：GROSS RAYMOND S; WILCOXEN KEITH M; OGLESBY RICHARD CHRISTOPHER
权利人:NEUROCRINE BIOSCIENCES INC
摘要:Methods of making substituted pyrazolopyrimidines generally and, more particularly, N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide. Such compounds have utility over a wide range of indications, including treatment of insomnia. In the practice of the present invention, improved techniques which do not require use and/or isolation of the pyrazole intermediate are disclosed, as well as improved techniques for making the reaction intermediates themselves. Such techniques offer significant advantages, including enhanced efficiency, particularly in the context of large scale manufacture.

专利号:US-9901901-B2
优先权日:2012-05-21
标 题 :Selective extraction of anions from solution
发明人：MEZEI GELLERT
权利人:WESTERN MICHIGAN UNIV RESEARCH FOUNDATION; THE BOARD OF TRUSTEES OF WESTERN MICHIGAN UNIV
摘要:A method of selectively extracting anions from an aqueous solution using an anion encapsulating aggregate formed upon the addition of a solvent, a copper contributor, a hydroxide contributor, a counterion contributor, and pyrazole to an aqueous solution containing the anions, or upon the addition of a solvent, a polymeric chain of [Cu II (μ-OH)(μ-pz)] ∞ and a counterion contributor to the aqueous solution. The aggregates include compounds of the formula cis Cu II x (OR 1 ) y (R 2 pz) z , where R 1 is H or an alkyl group, R 2 is H, or an alkyl group or a charged group, pz is pyrazolate and each of x, y, and z is an integer between about 1 and about 40. In addition, ligand-containing anion encapsulating aggregates can be formed by synthesis with a lig-and-bound pyrazole or by substituting the ligand-bound pyrazole for the pyrazole incorporated in the aggregate.

专利号:US-10087197-B2
优先权日:2012-05-21
标 题:Selective extraction of anions from solution
发明人：MEZEI GELLERT
权利人:WESTERN MICHIGAN UNIV RESEARCH FOUNDATION
摘要:A method of selectively extracting anions from an aqueous solution using an anion encapsulating aggregate formed upon the addition of a solvent, a copper contributor, a hydroxide contributor, an optional counterion contributor, and at least one encapsulating anion to an aqueous solution containing the anions, or upon the addition of a solvent, a polymeric chain of [CuII(μ-OH)(μ-ea)]∞ and optionally, a counterion contributor to the aqueous solution. The aggregates include compounds of the formula cis-CuIIx(OR1)y(R2ea)z, where R1 is H or an alkyl group, R2 is H, or an alkyl group or a charged group, ea is an encapsulating anion, and each of x, y, and z is equal to an integer between about 1 and 40, inclusive. In addition, anion encapsulating aggregates can be formed by synthesis with alternate encapsulating anions by substituting alternate encapsulating anions for the encapsulating anion incorporated in the aggregate.

专利号:WO-2009091832-A1
优先权日:2008-01-14
标题 :Synthesis of pyrazoles