CAS: 30246-33-4; (6R,7R)-7-Amino-3-(((5-Methyl-1,3,4-Thiadiazol-2-yl)Thio)Methyl)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid

上下游产品

7-Phenylacetylamino-3-(2-Methyl-1,3,4-Thiadiazol-5-yl)Thiomethyl-3-Cephem-4-Carboxylic Acid P-Methoxybenzyl Ester 107447-96-1
7-氨基头孢烷酸 7-Aminocephalosporanic Acid 957-68-6
(6R,7R)-Trimethylsilyl 7-(Trimethylsilyl)Amino-3-Acetoxy Methylceph-3-Em-4-Carboxylate 31461-04-8

(6R,7R)-Trimethylsilyl 7-(Trimethylsilyl)Amino-3-Acetoxy Methylceph-3-Em-4-Carboxylate置于吡啶,甲醇,碘代三甲硅烷体系中,用 1,1,2-三氯三氟乙烷(cfc-113) 作为反应溶剂,化学反应 2.67H,反应生成 7-氨基-3-{[(5-甲基-1,3,4-噻二唑-2-基)硫]甲基}头孢霉素烷酸
参考文献:Use Of Bistrimethylsilylated Intermediates In The Preparation Of Semisynthetic 7-Amino-3-Substituted Cephems. Expedient Syntheses Of A New 3-[(1-Methyl-1-Pyrrolidinio)Methyl]Cephalosporin
标题:Use Of Bistrimethylsilylated Intermediates In The Preparation Of Semisynthetic 7-Amino-3-Substituted Cephems. Expedient Syntheses Of A New 3-[(1-Methyl-1-Pyrrolidinio)Methyl]Cephalosporin
摘要:
DOI:10.1021/jo00240A009

专利信息

专利号:WO-2006008296-A1
优先权日:2004-07-19
标 题 :A process for the preparation of enzymatic catalysts, catalysts obtainable by this process and use thereof
发明人：TERRENI MARCO; VACCARO SUSANNA; ESTRUCH ILONA; PREGNOLATO MASSIMO; GIANNELLI ANTONIO; CARUSO SALVATORE
权利人:FIDIA FARMACEUTICI; INNOVATE BIOTECHNOLOGY S R L; TERRENI MARCO; VACCARO SUSANNA; ESTRUCH ILONA; PREGNOLATO MASSIMO; GIANNELLI ANTONIO; CARUSO SALVATORE
摘要:Herein described is a process for the preparation of enzymatic catalysts immobilised on epoxidic support, particularly suitable for the synthesis of β-lactamic antibiotics; the enzymatic catalysts obtainable by this process and their use.

专利号:US-9006421-B2
优先权日:2013-03-14
标题 :Cephalosporin compositions and methods of manufacture
发明人：LAI JAN-JI; PATHARE PRADIP M; KOLLA LAXMA; SORET ADRIEN F
权利人:CUBIST PHARM INC
摘要:Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising the conversion of a protected 7-amino group into a 7-carboxamide moiety in a single step.