烯丙基甲基碳酸酯置于palladium Diacetate 一氧化碳,三苯基膦体系中,用100%的收率获得3-丁烯酸甲酯 参考文献:Preparation Of Esters 标题:Preparation Of Esters 摘要:.Beta.,.Gamma.不饱和酯是通过在第viii族金属催化剂的存在下,将相应的.Beta.,.Gamma.-不饱和碳酸酯与一氧化碳反应制备的.
专利号:US-10011580-B2 优先权日:2016-04-21 标题:Diastereoselective synthesis of (±)-epianastrephin, (±)-anastrephin and analogs thereof 发明人:WALSE SPENCER S; KUZMICH DANIEL 权利人:US AGRICULTURE 摘要:A process for the synthesis of trans-fused γ-lactones having Formula (IV) from substituted cyclic ketones having Formula (I). A diastereoselective synthesis of (±)-epianastrephin (1) (wherein: R 1 is ethenyl, R 2 and R 3 is methyl, and n is 1), (±)-anastrephin (2) (wherein: R 2 is ethenyl, R 1 and R 3 is methyl and n is 1), and analogs thereof (wherein: R 1 is H, C 1-5 alkyl, C 2-6 alkenyl or C 2-6 alkynyl, R 2 is H, C 1-5 alkyl, C 2-6 alkenyl or C 2-6 alkynyl, R 1 and R 2 together with the carbon atom they are attached form a C 3-6 cycloalkyl ring, R 3 is C 1-5 alkyl and n is 0-2):
专利号:US-5859268-A 优先权日:1996-04-09 标 题:Process for the synthesis of α, β-unsaturated esters 发明人:ANGELICI ROBERT J; SHIH KUO-CHEN 权利人:UNIV IOWA STATE RES FOUND INC 摘要:The present invention provides a process for the synthesis of an α,β-unsaturated ester from a mono-olefin-ester using Fe(CO) 5 .
专利号:US-2023174477-A1 优先权日:2021-12-03 标题:Methods for synthesis of the tricyclic prostaglandin d2 metabolite methyl ester 发明人:DAI MINGJI; SIMS HUNTER 权利人:PURDUE RESEARCH FOUNDATION 摘要:Methods for the synthesis of a tricyclic-prostaglandin D 2 metabolite methyl ester or a pharmaceutically acceptable salt thereof.
专利号:US-9567293-B2 优先权日:2013-02-08 标题 :Combined synthesis of a nitrile-ester/acid and of a diester/diacid 发明人:DUBOIS JEAN-LUC; COUTURIER JEAN-LUC; BRANDHORST MARKUS 权利人:ARKEMA FRANCE 摘要:A method for the combined synthesis of a mono-unsaturated nitrile-ester(acid) and of a bi-functional carbonyl compound, wherein it includes a step including the cross metathesis mc1 of an unsaturated fatty acid/ester compound with an unsaturated nitrile compound, in which mc1 is performed with partial conversion such as to obtain and recover, separately, at least the following products: a mono-unsaturated nitrile-ester/acid and a symmetrical compound, diester or diacid respectively including a double bond located in the middle of the molecular chain of compound, and subsequently a step including the oxidation cleavage cp2 of the double bond of compound, such as to form a single type of carbonyl compound having formula R2-(CH2)n-COR′, in which R′ is H or OH, depending on the operating conditions selected for the oxidation cleavage cp2. Also, the production of monomers for the polymer industry.
专利号:US-2013172553-A1 优先权日:2009-11-25 标题 :Chiral synthesis of isoxazolines, isoxazoline compounds, and uses thereof 发明人:SIELECKI-DZURDZ THAIS; PRUITT JAMES 权利人:SIELECKI-DZURDZ THAIS; PRUITT JAMES; CPSI STOCKHOLDER TRUST 摘要:Processes for the chiral syntheses of isoxazolines and intermediates are described. Compounds prepared thereby, and methods of using the compounds are also described.
专利号:US-6022977-A 优先权日:1997-03-26 标 题 :Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids 发明人:ZHANG LIN-HUA; ANZALONE LUIGI; PESTI JAAN A; YIN JIANGUO 权利人:DU PONT PHARM CO 摘要:The present invention relates generally to a novel method for preparation of substituted isoxazolin-5-yl acetic acid in high optical purity from a stereoisomeric mixture of an esterified substituted isoxazolin-5-yl acetate. The products are useful in the synthesis of compounds for pharmaceuticals, especially the treatment of thrombolytic disorders, and agricultural products.
参考标题:Mno2 As A Terminal Oxidant In Wacker Oxidation Of Homoallyl Alcohols And Terminal Olefins 作者:Rodney A. Fernandes,Gujjula V. Ramakrishna,Venkati Bethi 摘要:Pdcl2/cro3/hcl Produced α,β-Unsaturated Ketones From Homoallyl Alcohols, The Present Method Provided Orthogonally The β-Hydroxy-Methyl Ketones. No Overoxidation Or Elimination Of Benzylic And/or β-Hydroxy Groups Was Observed. The Method Could Be Extended To The Oxidation Of Simple Terminal Olefins As Well, To Methyl Ketones, Displaying Its Versatility. An Application To The Regioselective Synthesis Of Gingerol Is
合成参考文献
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