CAS: 1857-19-8; 2-Amino-N,N-Dimethylacetamide

该化合物是一种有机化合物,具有氨化功能组特征,具有氨化物功能组特征,具有与氮原子相连的两个甲基组的中央乙酰胺结构,有助于二甲基替代.该化合物在室温中一般没有色状黄色液体,在水和各种有机溶剂中可溶解,反映其极性.氨基氨基亚基亚甲酰胺组的存在具有基本特性,允许其参与各种化学反应,包括核糖核生殖替代和凝聚反应.2-氨基乙酰胺经常用作有机合成的溶剂或再剂,并可作为制药和农用化学剂生产的中间体.其相对低的毒性和稳定活性中间体的能力使其在实验室环境中具有价值.然而,与许多氨基胺一样,它在某些条件下可能会发生水解,导致形成相应的酸和氨基胺.应当观察适当的处理和安全措施,因为其化学反应和潜在影响.

结构式图片

相似化合物

72287-77-5 200634-33-9 1857-20-1

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C&L通报

上下游产品

1,3-oxazolidine-2,5-dione dimethyl amine N-Benzyloxycarbonylglycine dimethylamide N-(Benzyloxycarbonyl)glycine N,N-dimethyl-2-[6-phenyl-2-(4-trifluoromethylphenyl)-4-pyrimidinylamino]acetamide 4-(2-hydroxybenzoyl)-N,N-dimethyl-1H-pyrrole-2-carboxamide 2-{3-[4-bromo-2-((3R,5S)-3,5-dimethyl-piperidine-1-carbonyl)-phenyl]-ureido}-N,N-dimethyl-acetamide 1-(4-[N-(2-Dimethylamino-2-oxoethylcarbamoyl)aminomethyl]-3-methylbenzoyl)-2,3,4,5-tetrahydro-1H-1-benzazepine

合成工艺路线路线简述

  • 合成目标产物 2-Amino-N,N-Dimethylacetamide 主要起始原料 Benzyl N-[(Dimethylcarbamoyl)Methyl]Carbamate
  • (文献来源)合成步骤主要原料 Benzyl N-[(Dimethylcarbamoyl)Methyl]Carbamate
N-[2-(二甲氨基)-2-氧乙基]-氨基甲酸-1,1-二甲基乙酯置于三氟乙酸体系中,用 二氯甲烷 用作溶剂,化学反应生成N,N-二甲基甘氨酰胺
参考文献:Highly Selective And Sensitive Detection Of Biogenic Defense Phytohormone Salicylic Acid In Living Cells And Plants Using A Novel And Viable Rhodamine-Functionalized Fluorescent Probe
标题:Highly Selective And Sensitive Detection Of Biogenic Defense Phytohormone Salicylic Acid In Living Cells And Plants Using A Novel And Viable Rhodamine-Functionalized Fluorescent Probe
摘要:Detecting Plant-Derived Signal Molecules Using Fluorescent Probes Is A Key Topic And A Huge Challenge For Scientists. Salicylic Acid (Sa),A Vital Plant-Derived Defense Hormone,Can Activate Global Transcriptional Reprogramming To Systemically Express A Network Of Prominent Pathogenesis-Related Proteins Against Invasive Microorganisms. This Strategy Is Called Systemic Acquired Resistance (Sar). Therefore,Monitoring The Dynamic Fluctuations Of Sa In Subcellular Microenvironments Can Advance Our Understanding Of Different Physiological And Pathological Functions During The Sa-Induced Sar Mechanism,Thus Benefiting The Discovery And Development Of Novel Immune Activators That Contribute To Crop Protection. Here,Detection Of Signaling Molecule Sa In Plant Callus Tissues Was First Reported And Conducted By A Simple Non-Fluorescent Rhodamine-Tagged Architecture Bearing A Flexible 2-Amino-N,N-Dimethylacetamide Pattern. This Study Can Markedly Advance And Promote The Usage Of Fluorescent Sa Probes For Distinguishing Sa In The Plant Kingdom.
Doi:10.1021/acs.Jafc.9B06771

海关参考信息

专利信息


专利号:US-2021395200-A1
优先权日:2018-11-16
标 题:Synthetic processes for the production of 1-((3s,4r)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl)-3-phenylurea
发明人:ORTIZ ADRIAN; BOROVIKA ALINA; KOLOTUCHIN SERGEI; LUZUNG MICHAEL R; NYE JEFFREY A; TAN YICHEN; ZARETSKY SERGE; ZHU JASON J; EASTGATE MARTIN D
权利人:BRISTOL MYERS SQUIBB CO
摘要:Highly efficient processes are provided for preparing key intermediates in the synthesis of compounds (I). The process are broadly applicable and can provide selected components having a variety of substituents. Some intermediates are claimed.

专利号:US-6465656-B2
优先权日:1999-10-21
标题 :Synthesis of 1,3,5-trisubstituted pyrazoles
发明人:ZHOU JIACHENG; OH LYNETTE MAY; CONFALONE PASQUALE N; LI HUI-YIN; MA PHILIP
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:A novel process for making 1,3,5-trisubstituted pyrazoles of the type shown below from appropriate phenyl hydrazines is described. n These compounds are useful as factor Xa inhibitors.

专利号:US-6329527-B1
优先权日:1999-10-21
标题 :Synthesis of 1,3,5-trisubstituted pyrazoles

专利号:US-2002055641-A1
优先权日:1999-10-21
标 题 :Synthesis of 1,3,5-trisubstituted pyrazoles

专利号:RU-2010796-C1
优先权日:1986-10-13
标 题:Method of synthesis of 3-propenylcepheme derivatives or theirs pharmaceutically acceptable salts

专利号:EP-0062161-A1
优先权日:1981-03-04
标 题 :Synthesis of amides using carbamic-acid salts
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合成参考文献


参考文献:10.1007/s00216-022-04021-7
摘要:Kuusinen S, Ekman M, Raiko K, Hannula H, Lyytikäinen A, Lahtinen S, Soukka T. Complement C1q in plasma induces nonspecific binding of poly(acrylic acid)-coated upconverting nanoparticle antibody conjugates. Analytical and Bioanalytical Chemistry. 2022 Mar 24;414(12):3741–9. doi: 10.1007/s00216-022-04021-7.
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