CAS: 30925-18-9; Boc-Asp-Obzl

相似化合物

92828-64-3 4779-31-1 7362-93-8

上下游产品

CAS号13726-67-5 B°C-L-天冬氨酸 | CAS号100-51-6 苯甲醇 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号104-15-4 对甲苯磺酸 | CAS号617-45-8 DL-天门冬氨酸 | CAS号275827-12-8 B°C-L-Asp(OPTMS... | CAS号13303-10-1 (4-硝基苯基)碳酸叔丁酯 | CAS号7362-93-8 L-天冬氨酸苄酯 | CAS号73821-95-1 B°C-L-天冬氨酸4-环己酯 | CAS号59768-74-0 B°C-L-天冬氨酸4-甲酯 | CAS号7362-93-8 L-天冬氨酸苄酯 | CAS号77302-72-8 B°C-L-2-氨基己二酸 | CAS号118399-28-3 (R)-5-氧代四氢呋喃-3-... | CAS号120042-11-7 N-[(1,1-二甲基乙氧基)... | CAS号124994-66-7 Butanoicacid, 2... | CAS号71447-58-0 (3S)-4-cyclopen...

Boc-L-Asp(Optmse)-Obzl置于四丁基氟化铵体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 Boc-L-天冬氨酸 1-苄酯
参考文献:Wagner,Michael; Kunz,Horst,Synlett,2000,# 3,P. 400-402
标题:Wagner,Michael; Kunz,Horst,Synlett,2000,# 3,P. 400-402

专利信息

专利号:US-7317129-B2
优先权日:2002-06-07
标 题:Chemical synthesis of reagents for peptide coupling
发明人：RAINES RONALD T; KIESSLING LAURA L; NILSSON BRADLEY L; HE YI; SOELLNER MATTHEW B; HINKLIN RONALD J
权利人:WISCONSIN ALUMNI RES FOUND
摘要:The present invention provides improved methods for synthesis of phosphinothiol reagents, as well as novel protected reagents, for use in formation of amide bonds, and particularly, for peptide ligation. The invention provides phosphine-borane complexes useful as reagents in the formation of amide bonds, particularly for the formation of an amide bond between any two of an amino acid, a peptide, or a protein.

专利号:WO-9526975-A1
优先权日:1994-03-30
标题 :Acyclic aliphatic branched alkyl groups as constituents of protective groups bound to side chains of amino-acid moieties, and their use in the preparation of peptide, polypeptide or protein structures
发明人：UNDEN ANDERS
权利人:UNDEN ANDERS
摘要:A protective group bound to a side chain of an amino-acid moiety, which group is an aliphatic acyclic branched alkyl group protecting a thiol, hydroxyl, or carboxyl group or an aliphatic acyclic branched alkoxycarbonyl group protecting an amino group or heterocyclic nitrogen, wherein the alkyl and alkoxy entities have from 6 to 18 carbon atoms and have at least two identical alkyl chains, is described. Further, the use of such a protective group bound to a side chain of an amino-acid moiety in the synthesis of peptides, polypeptides and proteins is disclosed.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-4130514-A
优先权日:1978-02-10
标 题:Synthesis of peptides
发明人：ENKOJI TAKASHI; SKIBBE MARTIN O
权利人:ARMOUR PHARMA
摘要:Peptides having adrenocorticotropic hormone activity and resin peptides useful in preparation of such peptides, particularly such peptides having asparagine at the carboxyl end thereof and more particularly such peptides having from 19 to 25 amino acids in their amino acid chains. The invention further involves new processes for the preparation of such peptides.

专利号:US-6569993-B1
优先权日:1998-04-15
标题 :Process for the preparation of resin-bound cyclic peptides
发明人：SLEDESKI ADAM W; MENCEL JAMES J
权利人:AVENTIS PHARMA SA
摘要:This invention is directed to a process for the solid phase, fragment-based synthesis of resin-bound cyclic peptide analogs of parathyroid hormones and analogs of parathyroid hormone-related proteins, which analogs contain at least one bridge between the side chains of two non-adjacent amino acid residues, and to peptide fragments useful therefor.

专利号:US-4755558-A
优先权日:1986-05-30
标题:Using internal marker
发明人：KALBAG SURESH M
权利人:BECKMAN INSTRUMENTS INC
摘要:A method is provided for quantitatively monitoring the deprotection and coupling reactions employed in the solid phase synthesis of peptides. The method entails synthesizing a peptide on a support matrix that has a first marker associated therewith. The amino acids employed in the peptide synthesis procedure have a second marker attached thereto, which can be the blocking group used for the amino acid. After the coupling or deprotection step a portion of the support matrix is processed to release first and second identifers from the first and second markers, respectively. The completeness of the coupling or deprotection step can be determined by comparing the relative amounts of the detected first and second identifiers. Novel compositions of matter are used in or produced during this method, including support matrixes having pyrolyzable markers attached thereto.