CAS: 40889-91-6; 2-Chloro-5-(Trifluoromethyl)Phenol

上下游产品

CAS号98-17-9 3-三氟甲基苯酚 | CAS号121-50-6 3-氨基-4-氯三氟甲苯 | CAS号166272-81-7 3-羟基-4-氯苯甲酸甲酯

3-氨基-4-氯三氟甲苯置于硫酸,Sodium Nitrite体系中,化学反应生成 4-氯-3-羟基三氟甲苯
参考文献:Chlorinated 3-Trifluoromethylphenols
标题:Chlorinated 3-Trifluoromethylphenols
摘要:
DOI:10.1021/ja01151A141

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.