CAS: 6011-14-9; 2-Aminoacetonitrile Hydrochloride

相似化合物

5466-22-8 540-61-4 85363-04-8

上下游产品

CAS号56464-51-8 2-[(1-甲基-3-氧代-3... | CAS号40513-43-7 2-氨基-4'-甲氧基苯乙酮 | CAS号3589-41-1 N-(苄氧羰基)氨基乙腈 | CAS号5521-58-4 2-氨基-5-甲基吡嗪 | CAS号142254-20-4 methyl N-(cyano... | CAS号4814-80-6 N-(氰甲基)乙酰胺 | CAS号20228-87-9 N-氰甲基-4-甲基苯磺酰胺 | CAS号1968-28-1 4H-Imidazol-4-o... | CAS号20301-57-9 2-chloro-N-(cya... | CAS号85363-04-8 2-(B°C-氨基)乙腈

氨基乙腈置于盐酸体系中,用 甲醇 作为反应溶剂,以96 %的收率获得产物氨基乙腈盐酸盐
参考文献:一种氨基乙腈盐酸盐的制备方法
标题:一种氨基乙腈盐酸盐的制备方法
摘要:本发明公开了一种氨基乙腈盐酸盐的制备方法,包括以下步骤:①将氯乙腈与氨反应得到氨基乙腈;②将步骤①得到的氨基乙腈与氯化氢,盐酸,盐酸甲醇或盐酸乙醇中的一种反应反应生成氨基乙腈盐酸盐.本发明设计的氨基乙腈盐酸盐的合成路线,以氯乙腈为原料,与氨反应反应生成氨基乙腈,再和酸反应反应生成氨基乙腈盐酸盐;反应原料不使用剧毒的氢氰酸或氰化钠,避免氢氰酸或氰化钠路线废水难处理的问题.

专利信息

专利号:US-2003073834-A1
优先权日:1997-11-03
标题:Purine compounds having PDE IV inhibitory activity and methods of synthesis
发明人：CAVALLA DAVID J; CHASIN MARK; HOFER PETER
摘要:The present invention comprises compounds having the general formula I: n n n wherein: n Y 1 is N or CH n Z is selected from the group consisting of alkyl groups such as alkylene groups such as CH 2 , CH 2 CH 2 , CH(CH 3 ); alkenyl groups such as CHâ•?CH; alkynyl groups such as C≡C; and NH, N(C 1 -C 3 alkyl), O, S, C(O)CH 2 and OCH 2 ; n R 1 and R 2 are selected from the group consisting of hydrogen and a C 1 -C 8 straight or branched alkyl or a C 3 -C 8 cycloalkyl; n R 3 is a C 1 -C 12 straight or branched alkyl; n R 4 is a C 3 -C 10 cycloalkyl optionally substituted with OH or C 3 -C 10 cycloalkenyl optionally substituted with OH; and n R 8 is a C 1 -C 8 straight or branched alkyl or a C 3 -C 8 cycloalkyl, optionally substituted with OH; n and methods of synthesis.

专利号:US-6977292-B2
优先权日:2000-09-01
标题 :Nucleophile-stable thioester generating compounds, methods of production and use
发明人：BOTTI PAOLO; BRADBURNE JAMES A; KENT STEPHEN B H
权利人:GRYPHON THERAPEUTICS
摘要:The invention is directed to nucleophile-stable thioester generating compounds comprising a carboxyester thiol. The compounds have wide applicability in organic synthesis, including the generation of peptide-, polypeptide- and other polymer-thioesters. The invention is particularly useful for generating activated-thioesters from precursors that are made under conditions in which strong nucleophiles are employed, such as peptides or polypeptides made using Fmoc SPPS, as well as multi-step ligation or conjugation schemes that require (or benefit from the use of) compatible selective approaches for directing a specific ligation or conjugation reaction of interest.

专利号:US-2021134398-A1
优先权日:2019-11-06
标题:Combinatorial Chemistry Computational System and Enhanced Selection Method
发明人：WISE JOHN G; VOGEL PIA D
权利人:UNIV SOUTHERN METHODIST
摘要:A method for identifying a potentially useful molecular combination includes applying a selection procedure to a compound to identify a first set of candidate molecules, the procedure including providing a chemical synthesis scheme, a virtual scaffold molecule of the compound, and a virtual reactant fragment to react with the scaffold molecule according to the scheme; preparing the reactant fragment and the scaffold molecule for analyzing combinations of them; designating a remaining scaffold subset and a remaining fragment subset if a product molecule can be formed from them; rotating the fragment subset about an axis connecting the scaffold subset and the fragment subset incrementally through 360 degrees; and identifying potentially useful combinations of the reactant fragment and the scaffold molecule; identifying a set of combinatorial fragments from the first set of candidates; and applying the selection procedure to the set of combinatorial fragments to identify a second set of candidate molecules.

专利号:US-5675008-A
优先权日:1992-09-03
标 题 :Excitatory amino acid receptor antagonists
发明人：BERTSCH CARL F; HUFF BRET; MARTINELLI MICHAEL J; ORNSTEIN PAUL L
权利人:LILLY CO ELI
摘要:This invention provides novel decahydroisoquinoline compounds which are useful as excitatory amino acid receptor antagonists and in the treatment of neurological disorders. This invention also provides synthetic methods for preparing decahydroisoquinolines, as well as, novel intermediates in the synthesis thereof.

专利号:WO-9929694-A1
优先权日:1997-12-12
标题:Purine compounds having pde iv inhibitory activity and methods of synthesis

专利号:EP-1045850-A1
优先权日:1997-12-12
标题:Purine compounds having pde iv inhibitory activity and methods of synthesis