CAS: 614-77-7; 1-(O-Tolyl)Urea

上下游产品

CAS号10532-63-5 (2-methylphenyl... | CAS号590-28-3 氰酸钾 | CAS号95-53-4 邻甲苯胺 | CAS号917-61-3 氰酸钠 | CAS号556-89-8 硝基脲 | CAS号617-07-2 对称-DI-O-苯甲基脲 | CAS号57-13-6 尿素 | CAS号636-21-5 邻甲苯胺盐酸盐 | CAS号7664-93-9 硫酸 | CAS号45892-06-6 (2-methylphenyl... | CAS号614-68-6 邻甲苯异氰酸酯 | CAS号2028-34-4 o-methylbenzene... | CAS号15940-63-3 Hydrazinecarbox... | CAS号106037-36-9 4-氨基-3-甲基苯甲酰胺 | CAS号13558-76-4 1-(2-chloroacet... | CAS号617-07-2 对称-DI-O-苯甲基脲

N-邻甲苯基硫脲置于trans-3,5-Dihydroperoxy-3,5-Dimethyl-1,2-Dioxolane,水,Potassium Hydroxide体系中,用 乙腈 作为反应溶剂,化学反应 0.25H,以81%的收率获得产物邻甲苯基脲
参考文献:Selective And Facile Oxidative Desulfurization Of Thioureas And Thiobarbituric Acids With Singlet Molecular Oxygen Generated From Trans-3,5-Dihydroperoxy-3,5-Dimethyl-1,2-Dioxolane
标题:Selective And Facile Oxidative Desulfurization Of Thioureas And Thiobarbituric Acids With Singlet Molecular Oxygen Generated From Trans-3,5-Dihydroperoxy-3,5-Dimethyl-1,2-Dioxolane
摘要:An Efficient And Facile Procedure Using Trans-3,5-Dihydroperoxy-3,5-Dimethyl-1,2-Dioxolane Has Been Developed For Oxidative Desulfurization Of Thioureas And Thiobarbituric Acids. The Reactions Proceeded Smoothly Very Fast Under Mild Conditions In Basic Media At Room Temperature To Afford The Respective Ureas In Excellent Yields. Simple Procedure And Work Up,Mild Conditions,High Yields,Short Reaction Times,Use Of Highly Potent And Non-Toxic Oxidant Are The Main Merits Of The Present Method.[graphics].
DOI:10.1080/17415993.2015.1082181

专利信息

专利号:WO-9740025-A1
优先权日:1996-04-19
标 题 :Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
发明人：DOERWALD FLORENCIO ZARAGOZA
权利人:NOVO NORDISK AS; DOERWALD FLORENCIO ZARAGOZA
摘要:A solid phase method for the synthesis of a plurality of differently substituted 1,2,3-triazoles with a wide variety of side-chain substituents as compounds of potential therapeutic interest. The 1,2,3-triazoles are prepared by acylation of a substrate-bound primary or secondary amine with a 3-oxoalkanoic acid and reaction of the resulting amide with a primary amine under dehydrating conditions to give an enamine. Treatment of this substrate-bound enamine with a sulfonyl azide in the presence of a base gives the corresponding 1,2,3-triazoles. These may be screened on the substrate or cleaved from the substrate and then screened in solution. The efficient synthesis of a wide variety of 1,2,3-triazoles using automated synthesis technology of the present method makes these compounds attractive candidates for the generation and rapid screening of diverse triazole-based libraries. The method disclosed here provides an easy and fast access to highly diverse heterocyclic compounds of therapeutic interest, amenable to automatization.

专利号:CN-112250661-A
优先权日:2020-11-18
标题 :A kind of method for catalyzing synthesis of lactide

专利号:CN-112250661-B
优先权日:2020-11-18
标题:A kind of method for catalyzing synthesis of lactide

专利号:CN-1498885-A
优先权日:2002-10-29
标 题 :Synthesis of 3-acylaminopyrazoles

专利号:CN-107235917-A
优先权日:2016-12-31
标题 :A class of licochalcone A dihydropyrimidine compounds with antitumor activity and its synthesis method