CAS: 63399-77-9; (R)-2-Methylpyrrolidine-2-Carboxylic Acid

相似化合物

123053-48-5 42856-71-3 203869-80-1

上下游产品

CAS号848488-83-5 H-DL-(αMe)Pro-NH2 | CAS号1186301-79-0 tert-butyl (R)-... | CAS号123053-47-4 (3S,7aR)-3-(ter... | CAS号6931-10-8 5-methyl-1-oxid... | CAS号132235-34-8 (1'R,2R,2'S,5'R... | CAS号132235-38-2 (1'R,2R,2'S,5'R... | CAS号5891-21-4 5-氯-2-戊酮 | CAS号123053-46-3 (2R,5R)-tert-bu... | CAS号166170-15-6 1-叔丁氧羰基-(R)-2-甲...

3,4-Dihydro-5-Methyl-2H-Pyrrole 1-Oxide置于palladium On Activated Charcoal 盐酸,氢气,双氧水,Sodium Carbonate体系中,用 甲醇,丙酮 作为反应溶剂,45.0 °C,101.33 Kpa 条件下,反应 134.0H,反应生成 (R)-2-甲基脯氨酸
参考文献:Shatzmiller,Shimon; Dolithzky,Ben-Zion; Bahar,Eliezer,Liebigs Annalen Der Chemie,1991,# 4,P. 375-379
标题:Shatzmiller,Shimon; Dolithzky,Ben-Zion; Bahar,Eliezer,Liebigs Annalen Der Chemie,1991,# 4,P. 375-379

专利信息

专利号:WO-2008098280-A1
优先权日:2007-02-16
标题:Methods for the synthesis of dicarba bridges in growth hormone peptides
发明人：ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
权利人:POLYCHIP PHARMACEUTICALS PTY; UNIV MONASH; ROBINSON ANDREA JANE; VAN LIEROP BIANCA; WHELAN AMANDA
摘要:The invention relates to peptides comprising the carboxy terminal sequence of a growth hormone or an analogue of such a peptide in which the disulfide bridge is replaced by a dicarba bridge. Compositions containing such dicarba bridged peptides and method of treating obesity in an animal such as a human comprising administration of such dicarba bridged peptides are also disclosed.

专利号:US-2023364251-A1
优先权日:2020-08-06
标 题:Methods for the synthesis of protein-drug conjugates
发明人：BORCHARDT ALLEN; HUGHES ROBERT MICHAEL
权利人:CIDARA THERAPEUTICS INC
摘要:The present invention relates to intermediates and methods for synthesizing protein-drug conjugates that can be used for the treatment of diseases and related conditions.

专利号:US-7230124-B2
优先权日:2001-08-24
标题:Ascorbic acid compounds, methods of synthesis and application use thereof
发明人：ROOMI WAHEED M; NETKE SHRIRANG; IVANOV VADIM; NIEDZWIECKI ALEKSANDRA; RATH MATTHIAS
权利人:ROOMI WAHEED M; NETKE SHRIRANG; IVANOV VADIM; NIEDZWIECKI ALEKSANDRA; RATH MATTHIAS
摘要:A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The composition so described is used to prevent the degradation of extracellular matrix, stabilize connective tissue, is used to as an antioxident, and is used for treating damage to skin comprising applying the topical composition to the skin.

专利号:US-2008188553-A1
优先权日:2007-02-06
标题:Novel ascorbic acid compounds, methods of synthesis and application use thereof
发明人：ROOMI WAHEED M
权利人:ROOMI WAHEED M
摘要:A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The composition so described is used to prevent the degradation of extracellular matrix, stabilize connective tissue, is used to as an antioxidant, and is used for treating damage to skin comprising applying the topical composition to the skin.

专利号:KR-20230118799-A
优先权日:2020-08-06
标题 :Chemical Synthesis of Large Enantiomer Proteins and Uses Thereof

专利号:IL-300418-A
优先权日:2020-08-06
标题 :Chemical synthesis of large and useful mirror image proteins