CAS: 66684-58-0; 1,2,3-Trifluoro-5-Nitrobenzene

上下游产品

3,4,5-trifluoro aniline 6-nitro-2,3,4-trifluoroaniline pentafluoronitrobenzen 2,3,4,5-tetrafluoro-1-nitrobenzene 3-(2,6-difluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hexane (1α,5α,6α)-3-(2,6-difluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hexan-1-ol (1α,5α,6α)-3-(2,6-difluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-6-carboxylic acid tert-butyl ester [(1α,5α,6α)-3-(2,6-difluoro-4-nitrophenyl)-3-azabicyclo[3.1.0]hex-6-yl]carbamic acid tert-butyl ester

2,3,4-三氟-6-硝基苯胺置于亚硝酸特丁酯,盐酸体系中,用 Dmf (N,N-Dimethyl-Formamide),水 作为反应溶剂,化学反应 4.0H,以60%的收率获得产物3,4,5-三氟硝基苯
参考文献: A Process For The Preparation Of 3,4,5-Trifluoronitrobenzene[fr] Procede De Preparation De 3,4,5-Trifluoronitrobenzene
标题: A Process For The Preparation Of 3,4,5-Trifluoronitrobenzene[fr] Procede De Preparation De 3,4,5-Trifluoronitrobenzene
摘要:本发明涉及一种制备式为(1)的3,4,5-三氟硝基苯的过程.该过程涉及直接转化,最终以非常好的产量一致地制备出所述化合物.

专利信息

专利号:US-9233989-B2
优先权日:2011-10-11
标题:Sila analogs of oxazolidinone derivatives and synthesis thereof
发明人：REDDY DUMBALA SRINIVASA; BALAMKUNDU SEETHARAM SINGH; RAMESH REMYA
权利人:COUNCIL SCIENT IND RES
摘要:The invention discloses silaanalogs of oxazolidinone compounds, to pharmaceutical compositions and to the synthesis of the oxazolidinone derivatives of formula I. The invention further relates to methods of treating a subject suffering with gram positive pathogens including those resistant to methicillin and vancomycin using the compound(s) or modulation of coagulation properties of blood-clotting cascade or compositions of the oxazolidinone derivatives of the invention.

专利号:WO-2008090570-A1
优先权日:2007-01-25
标题 :Novel antimicrobials
发明人：JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KAUR GURMEET; KANWAR SANDEEP; MAGADI SITARAM KUMAR
权利人:PANACEA BIOTEC LTD; JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KAUR GURMEET; KANWAR SANDEEP; MAGADI SITARAM KUMAR
摘要:The present invention relates to novel phenyl oxazolidinone compounds of formula (I) or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of formula (I) or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of formula I and methods of using them. The compounds of the present invention are useful as antimicrobial agents, effective against a number of aerobic and/or anaerobic Gram positive and/or Gram negative pathogens such as multi drug resistant Staphylococcus spp., Streptococcus spp., Enterococcus spp., Bacterioides spp., Clostridia spp., H. influenza, Moraxella Spp., as well as acid-fast organisms such as Mycobacterium tuberculosis and the like.

专利号:US-8841306-B2
优先权日:2008-11-20
标 题:Antimicrobials
发明人：JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KANWAR SANDEEP; MAGADI SITARAM KUMAR; SHARMA SUDHIR KUMAR
权利人:JAIN RAJESH; TREHAN SANJAY; DAS JAGATTARAN; KANWAR SANDEEP; MAGADI SITARAM KUMAR; SHARMA SUDHIR KUMAR; PANACEA BIOTEC LTD
摘要:The present invention relates to novel phenyl oxazolidinone compounds of formula I, their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of formula I or their pharmaceutically acceptable analogs, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of formula I and methods of using them. The compounds of the present invention are useful as antimicrobial agents, effective against a number of aerobic and/or anaerobic Gram positive and/or Gram negative pathogens such as multi drug resistant species of Staphylococcus, Streptococcus, Enterococcus, Bacterioides, Clostridia, H. influenza, Moraxella , acid-fast organisms such as Mycobacterium tuberculosis as well as Linezolid resistant species of Staphylococcus and Enterococcus.

专利号:CN-101811973-A
优先权日:2010-04-23
标 题 :A method for the synthesis of halogenated arylamines by highly selective liquid-phase hydrogenation under solvent-free conditions

专利号:US-2014296133-A1
优先权日:2011-10-11
标题:Sila analogs of oxazolidinone derivatives and synthesis thereof

专利号:JP-6162704-B2
优先权日:2011-10-11
标 题 :Sila analogs of oxazolidinone derivatives and their synthesis